페닐유레아
N-페닐우레아 · 페닐유레아 · 1-Phenylurea · VH · N-PHENYLUREA · Urea, N-phenyl- · phenyl-ure · PHENYLUREA
식별자 및 물리적 특성
| CAS No. | 64-10-8 |
|---|---|
| 분자식 | C7H8N2O |
| 평균 분자량 | 136.15 g/mol |
| 단동위원소 질량 | 136.06366288 g/mol |
| SMILES | NC(=O)Nc1ccccc1 |
| InChIKey | LUBJCRLGQSPQNN-UHFFFAOYSA-N |
| PubChem CID | 6145 |
| ChEMBL | CHEMBL168445 |
| ChEBI | CHEBI:180992 |
| EC No. | 200-576-5 |
| DTXSID | DTXSID8042507 |
| 현지명 | 페닐유레아 |
화학 및 물리적 성질
| XLogP | 0.8 |
|---|---|
| 극성 표면적 | 55.1 |
| 수소 결합 공여자 수 | 2 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 1 |
| 무거운 원자 수 | 10 |
| 형식 전하 | 0 |
| 복잡도 | 119 |
| SpringerMaterials Properties | 15N nuclear magnetic resonance spectrum |
| Physical Description | Phenyl urea pesticide, liquid, poisonous appears as a liquid dissolved or suspended in a liquid carrier. Contains any of several related compounds (Diuron, Fenuron, Linuron, Neburon, Siduron, Monuron) formally derived from urea. Carrier is water emulsifiable. Toxic by inhalation, skin absorption, or ingestion. Obtain the technical name of the specific pesticide and carrier from the shipping papers and contact CHEMTREC, 800-424-9300 for response information. |
| 녹는점 | 145-147 °C(lit.) |
| 끓는 점 | 238 °C |
| 밀도 | 1,302 g/cm3 |
| 증기 밀도 | >1 (vs air) |
| 굴절률 | 1.5769 (estimate) |
| 인화점 | 238°C |
| 저장 조건 | Keep in dark place,Sealed in dry,Room Temperature |
| 용해도 | H2O: 10 mg/mL, 투명 |
| pKa(산도 계수) | 13.37±0.50(Predicted) |
| 물리적 상태 | 분말, 결정 및/또는 덩어리 |
| 색상 | 흰색에서 밝은 노란색 |
| 용해도 | 물에 용해됩니다. |
| Merck | 14,7319 |
| BRN | 1934615 |
| 안정성 | 안정적인. 강한 산화제와 호환되지 않습니다. |
| InChI | 1S/C7H8N2O/c8-7(10)9-6-4-2-1-3-5-6/h1-5H,(H3,8,9,10) |
| InChIKey | LUBJCRLGQSPQNN-UHFFFAOYSA-N |
| SMILES | NC(=O)Nc1ccccc1 |
| EPA | Urea, phenyl- (64-10-8) |
화학적 성질
Colorless needle-like crystals or off-white powder. Melting point 147°C(decomposition), soluble in hot water, hot alcohol, ether, ethyl acetate and acetic acid.
안전 및 규제
| GHS 분류 | WarningH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 47 reports by companies from 3 notifications to the ECHA C&L Inventory. |
|---|---|
| 규제 정보 | Chemical: Urea, N-phenyl-Phenylurea: Does not have an individual approval but may be used under an appropriate group standard |
| 운송 라벨(DOT) | Poison |
| 화재 위험 | Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]: |
| 건강 유해성 | Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]: |
| 반응성 그룹 | Amides and Imides |
| Reactivity Profile | Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). Contains any of several related compounds (Diuron, Fenuron, Linuron, Neburon, Siduron, Monuron) formally derived from urea. |
| Air and Water Reactions | No rapid reaction with air. No rapid reaction with water. |
| Hazard Classes and Categories | Acute Tox. 4 (100%) |
| 소화 | Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]: |
| 응급 처치 | Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]: |
| 비화재 누출 대응 | Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]: |
| Isolation and Evacuation | Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]: |
| Personal Protective Equipment (PPE) |
용도
용도
Phenylureas are commonly used soil-applied herbicides for control of grass and small-seeded broadleaf weeds.
일반 설명
Phenylurea is the core structural unit of phenylurea herbicides (PUHs), such as diuron, fenuron, linuron, monuron, isoproturon, monolinuron and chlortoluron. As photosynthesis inhibitors, phenylurea herbicides are widely used in various crops for the pre-emergence and post-emergence control of broadleaf and annual weeds. These herbicides are used on major food crops, including maize (Zea mays) and tomato (Solanum lycopersicum), to control weeds such as lamb’s quarters (Chenopodium album), amaranth (Amaranthus spp.) and barnyard grass (Echinochloa crus-galli)[1].
제조 및 합성 방법
제조 방법
Phenylurea is synthesized by the reaction of aniline and urea. Put urea, hydrochloric acid and aniline into the reaction pot, heat and stir, reflux at 100-104°C for 1 hour, add water and stir, cool, filter, wash the filter cake with water, and dry to obtain the finished product of phenylurea.