D-Lactic Acid (HCID 61503)

개요

(R)-lactic acid is an optically active form of lactic acid having (R)-configuration. It has a role as an Escherichia coli metabolite and a human metabolite. It is a conjugate acid of a (R)-lactate. It is an enantiomer of a (S)-lactic acid.

이름 및 식별자

우선 이름: D-Lactic Acid
IUPAC: (2R)-2-hydroxypropanoic acid
현지명: D-(-)-젖 산
영어명: (R)-Lactate
분자식: C3H6O3
분자량: 90.08

이름 및 동의어

D-Lactic acid10326-41-7(R)-2-Hydroxypropanoic acidD-(-)-Lactic acid(2R)-2-hydroxypropanoic acid(R)-Lactic acid(-)-Lactic acidPropanoic acid, 2-hydroxy-, (2R)-(R)-2-Hydroxypropionic acid(R)-(-)-Lactic acidD-MilchsaeureD-2-Hydroxypropanoic acid

이름 더 보기

D-(-)-젖산(R)-젖산D-MILK ACID(r)-lactateD-（& # 8722D-LaCLic Acid(R)-lacticaciD(-)LACTIC ACID

Lactic acid, D-D-2-Hydroxypropionic acid(R)-alpha-Hydroxypropionic acidDTXSID00470303Q6M5SET7WDTXCID8027030CHEBI:42111RefChem:584137

데이터베이스 식별자

CAS: 10326-41-7
PubChem CID: 61503
DTXSID: DTXSID0047030
ChEMBL: CHEMBL358850
ChEBI: CHEBI:42111
UNII: 3Q6M5SET7W
EC Number: 233-713-2
Nikkaji: J9.141C

물성

구조 계산 물성

XLogP: -0.7
극성 표면적: 57.5 Å²
수소 결합 공여자 수: 2
수소 결합 수용자 수: 3
회전 가능 결합 수: 1
무거운 원자 수: 6
형식 전하: 0
복잡도: 59.1

실험 및 물리화학적 성질

SpringerMaterials PropertiesCoriolis coupling

Melting Point52.8 °C

Physical DescriptionSolid

Dissociation Constants · 2건

3.861

3.83

물리화학적 성질

녹는점: 52.8 ° · 52.8°
끓는 점: 227.6 · 227.6±0.0 °C(Predicted)
밀도: 1.276 · 1.276±0.06 g/cm3(Predicted)
증기압: 3.8 Pa · 3.8Pa at 25℃
굴절률: 1.428 to · 1.4280 to 1.4320
FEMA: 2611 · 2611 | LACTIC ACID
저장 조건: -20 °C · -20°C
용해도: 2 O: · H2O: 0.1 g/mL, 투명, 무색
물리적 상태: 저융점 고체
산도 계수 (pKa): 3.83 · pK = 3.83(at 25℃)
색상: 흰색에서 황백색까지
냄새: 무취의 산성
수용성: 물에 용해됨(50mg/ml)
Merck: 14 · 14,5335
JECFA Number: 930 · 930
BRN: 1720252 · 1720252
안정성: 흡습성
InChI: 1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m1/s1
InChIKey: JVTAAEKCZFNVCJ-UWTATZPHSA-N
SMILES: C[C@@H](O)C(O)=O
LogP: -0.54 at · -0.54 at 20℃
EPA: 2 · Propanoic acid, 2-hydroxy-, (2R)- (10326-41-7)

안전 및 규제

GHS 분류

GHS Classification · 6건

Danger

H314 (10.4%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P264+P265, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P332+P317, P362+P364, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 48 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

유해성 정보

Regulatory Information · 4건

Chemical: Propanoic acid, 2-hydroxy-, (2R)-

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: Active Update: 22-09-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/12317

Propanoic acid, 2-hydroxy-, (2R)-: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationEvaluation - Lactic acid isomers

Hazard Classes and Categories · 2건

Skin Corr. 1C (10.4%)

Skin corrosion/irritation - Category 1

독성 정보

Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).

안전 데이터

wgk: 3
tsca: TSCA listed
ridadr: UN 3265 8/PG III
HS 번호: 2918110000
risk_code: 38-41
hazard_code: Xi
safety_code: 26-39
포장분류: III
위험 등급: 8
기존화학 물질: KE-21804
F 고인화성물질: 3-10
Hazard Classifications: Eye Dam. 1Skin Corr. 1C
스토리지 클래스: 8A - Combustible corrosive hazardous materials

화학 및 산업

약리 정보

Tissue LocationsBladder

Cellular LocationsExtracellular

Metabolite PathwaysLeigh Syndrome

용도 및 제조

UsesThis is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation.

General Manufacturing InformationPropanoic acid, 2-hydroxy-, (2R)-: ACTIVE

응용 분야 · 1건

용도D-(-)-Lactic acid is a useful biochemical for proteomics research. It is also used in the production of chiral drug and in the chemical synthesis. Lactic acid is used as a reagent in organic synthesis (in the manufacture of adhesives). It is used in the leather, textile, and tanning industries. It may be used as a plasticizer, a catalyst, or an acidifying agent. Lactic acid has even been used as a flavoring agent in the manufacture of tobacco products.