Nickel Dihydroxide

HCID 61534CAS 11113-74-9

기본 정보

표준 SMILES
[Ni+2].[OH-].[OH-]
InChIKey
BFDHFSHZJLFAMC-UHFFFAOYSA-L
분자식
H2NiO2
평균 분자량
92.708 g/mol
단동위원소 질량
91.940821

이름 및 식별자

우선 이름
Nickel Dihydroxide
IUPAC
nickel(2+) dihydroxide
영어명
Nickel hydroxide
분자식
HNiO-
분자량
75.7

이름 및 동의어

Nickel(II) hydroxideNICKEL HYDROXIDEGreen nickel oxideNickelous hydroxideNickel(2+) hydroxideDTXSID90274011L8UW92NW6JNiOH2NICKELDIOLRefChem:165670DTXCID00196497234-348-1
이름 더 보기
235-008-512054-48-7Nickel Dihydroxidenickel hydroxide (II)NICKEL HYDROXIDE (Ni(OH)2)nickel(2+);dihydroxide11113-74-9nickel(II)hydroxide

데이터베이스 식별자

CAS
11113-74-9、12054-48-7
PubChem CID
61534
UNII
L8UW92NW6J
EC Number
234-348-1、235-008-5
Nikkaji
J10.442F

물성

구조 계산 물성

극성 표면적
2 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
2
회전 가능 결합 수
0
무거운 원자 수
3

실험 및 물리화학적 성질

Density · 3건

4.1 at 68 °F (USCG, 1999) - Denser than water; will sink

4.1

4.1 @25 °C

Color/Form · 3건

Black powder

Green crystals, hexagonal

Light green microcrystalline powder

Solubility · 3건

SOL IN DIL ACIDS, IN AMMONIA

SOL IN AMMONIUM HYDROXIDE, ACIDS

0.013 G/100 CC COLD WATER

Flash Point · 2건

Ignites in air at about 752.0 °F (USCG, 1999)

752 °F

Decomposition · 2건

DECOMP ABOVE 200 °C TO FORM NICKEL OXIDE & WATER.

Toxic gases and vapors (such as nickel carbonyl) may be released ... in the decomp of nickel cmpd. /Nickel & sol nickel cmpd/

Melting Point · 2건

446 °F (USCG, 1999)

Decomposes at 230 °C

물리화학적 성질

EPA
Nickel hydroxide (11113-74-9)

안전 및 규제

GHS 분류

GHS Classification · 6건

Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral];H315: Causes skin irritation [Warning Skin corrosion/irritation];H317: May cause an allergic skin reaction [Warning Sensitization, Skin];H332: Harmful if inhaled [Warning Acute toxicity, inhalation];H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory];H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity];H350i: May cause cancer by inhalation [Danger Carcinogenicity];H360D ***: May damage the unborn child [Danger Reproductive toxicity];H372 **: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure];H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard];H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P203, P233, P260, P261, P264, P270, P271, P272, P273, P280, P284, P301+P317, P302+P352, P304+P340, P317, P318, P319, P321, P330, P332+P317, P333+P317, P342+P316, P362+P364, P391, P403, P405, and P501 (click each P-code to see the statement)

Danger

유해성 정보

Regulatory Information · 6건

Chemical: Nickel hydroxide (Ni(OH)2)

Hazard Traits - Carcinogenicity; Reproductive Toxicity; Respiratory Toxicity;Authoritative List - EC Annex VI CMRs - Cat. 1A; EC Annex VI CMRs - Cat. 1B; EC Annex VI Resp. Sens. - Cat. 1;Report - if used as a fragrance or flavor ingredient

Hazard Traits - Carcinogenicity; Reproductive Toxicity; Respiratory Toxicity;Authoritative List - EC Annex VI CMRs - Cat. 1A; EC Annex VI CMRs - Cat. 1B; EC Annex VI Resp. Sens. - Cat. 1;Report - if used as a fragrance or flavor ingredient

Nickel hydroxide (Ni(OH)2) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Nickel hydroxide (Ni(OH)2) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 10-11-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/15359;Status: Cease Manufacture Update: 22-01-2013 https://echa.europa.eu/registration-dossier/-/registered-dossier/1686;Status: Cease Manufacture Update: 27-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/25346

Restricted substance: Nickel dihydroxide;EC: 235-008-5;Restriction condition document: PDF link

Other Safety InformationIMAP assessments - Nickel hydroxide (Ni(OH)2): Human health tier II assessment
DOT LabelClass 9
Fire HazardsSpecial Hazards of Combustion Products: None known;Behavior in Fire: Converts to black nickelic oxide (Ni 2 O 3 ). (USCG, 1999)
Fire PotentialDoes not readily ignite.
Health Hazards · 1건

INHALATION: Irritant to mucous membrane of upper respiratory tract. EYES: Irritant to conjunctiva. SKIN: May cause sensitization. Sensation of burning or itching, followed by erythema and nodular eruption-fingers, wrists, and forearms. (USCG, 1999)

안전 및 보호

Fire Fighting · 1건

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:;CAUTION: Fire involving Safety devices (UN3268) and Fire suppressant dispersing devices (UN3559) may have a delayed activation and a risk of hazardous projectiles. Extinguish the fire at a safe distance.;SMALL FIRE: Dry chemical, CO2, water spray or regular foam.;LARGE FIRE: Water spray, fog or regular foam. Do not scatter spilled material with high-pressure water streams. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal.;FIRE INVOLVING TANKS: Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)

First Aid · 1건

Consult a physician.;INHALATION: Remove from source.;EYES: Wash with copious amounts of water and get medical attention.;SKIN: Wash with soap and water.;INGESTION: Give 2 to 3 glasses of water and induce vomiting. Consult physician. (USCG, 1999)

Fire Fighting Procedures · 2건

Use agent based on the substance that is burning since nickel hydroxide itself does not burn or burns with difficulty.

If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. Material itself does not burn or burns with difficulty. If material not involved in fire: Keep material out of water and sewers. Build dikes to contain flow as necessary; Personnel protection: Keep upwind; wear appropriate chemical protective gloves, boots and goggles; avoid breathing vapors or dusts; wash away any material which may have contacted the body with copious amt of water or soap and water.

Storage Conditions · 1건

PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/

Cleanup Methods · 2건

Environmental considerations- Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water; Environmental considerations- Water spill: Neutralize with agricultural lime (CaO), crushed limestone (CaCO3), or sodium bicarbonate (NaHCO3); adjust pH to neutral (pH= 7); use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates

PRECAUTIONS FOR "CARCINOGENS": A high-efficiency particulate arrestor (HEPA) or charcoal filters can be used to minimize amt of carcinogen in exhausted air ventilated safety cabinets, lab hoods, glove boxes or animal rooms ... Filter housing that is designed so that used filters can be transferred into plastic bag without contaminating maintenance staff is avail commercially. Filters should be placed in plastic bags immediately after removal ... The plastic bag should be sealed immediately ... The sealed bag should be labelled properly ... Waste liquids ... should be placed or collected in proper containers for disposal. The lid should be secured & the bottles properly labelled. Once filled, bottles should be placed in plastic bag, so that outer surface ... is not contaminated ... The plastic bag should also be sealed & labelled. ... Broken glassware ... should be decontaminated by solvent extraction, by chemical destruction, or in specially designed incinerators. /Chemical Carcinogens/

Nonfire Spill Response · 1건

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:;Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent dust cloud. For Asbestos, avoid inhalation of dust. Cover spill with plastic sheet or tarp to minimize spreading. Do not clean up or dispose of, except under supervision of a specialist.;SMALL DRY SPILL: With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area.;SMALL SPILL: Pick up with sand or other non-combustible absorbent material and place into containers for later disposal.;LARGE SPILL: Dike far ahead of liquid spill for later disposal. Cover powder spill with plastic sheet or tarp to minimize spreading. Prevent entry into waterways, sewers, basements or confined areas. (ERG, 2024)

독성 정보

TreatmentExcess exposure to nickel is usually handled by preventing further exposure and symptomatic treatment. Nickel poisoning may also be treated using chelation therapy with sodium diethyldithiocarbamate. (L42)
Health Effects · 1건

The most common harmful health effect of nickel in humans is an allergic reaction. This usually manifests as a skin rash, although some people experience asthma attacks. Long term inhahation of nickel causes chronic bronchitis and reduced lung function, as well as damage to the naval cavity. Ingestion of excess nickel results in damage to the stomach, blood, liver, kidneys, and immune system, as well as having adverse effects on reproduction and development. (L41)

Adverse Effects · 1건

Skin Sensitizer - An agent that can induce an allergic reaction in the skin.;Asthma - Reversible bronchoconstriction (narrowing of bronchioles) initiated by the inhalation of irritating or allergenic agents.;IARC Carcinogen - Class 1: International Agency for Research on Cancer classifies chemicals as established human carcinogens.;NTP Carcinogen - Known to be a human carcinogen.

Exposure RoutesInhalation (L41) ; oral (L41) ; dermal (L41)
Toxicity Summary · 1건

Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promote cell proliferation. Nickel has a high affinity for chromatin proteins, particularly histones and protamines. The complexing of nickel ions with heterochromatin results in a number of alterations including condensation, DNA hypermethylation, gene silencing, and inhibition of histone acetylation, which have been shown to disturb gene expression. Nickel has also been shown to alter several transcription factors, including hypoxia-inducible transcription factor, activating transcription factor, and NF-KB transcription factor. There is also evidence that nickel ions inhibit DNA repair, either by directly inhibiting DNA repair enzymes or competing with zinc ions for binding to zinc-finger DNA binding proteins, resulting in structural changes in DNA that prevent repair enzymes from binding. Nickel ions can also complex with a number of cellular ligands including amino acids, peptides, and proteins resulting in the generation of oxygen radicals, which induce base damage, DNA strand breaks, and DNA protein crosslinks. (L41, A40)

Signs and SymptomsSymptoms of nickel poisoning include headache, nausea, vomiting, dizziness, irritability, and difficulty sleeping, followed by chest pains, sweating, rapid heart beat, and a dry cough. (L42)

규제 정보

Regulatory Information · 6건

Chemical: Nickel hydroxide (Ni(OH)2)

Hazard Traits - Carcinogenicity; Reproductive Toxicity; Respiratory Toxicity;Authoritative List - EC Annex VI CMRs - Cat. 1A; EC Annex VI CMRs - Cat. 1B; EC Annex VI Resp. Sens. - Cat. 1;Report - if used as a fragrance or flavor ingredient

Hazard Traits - Carcinogenicity; Reproductive Toxicity; Respiratory Toxicity;Authoritative List - EC Annex VI CMRs - Cat. 1A; EC Annex VI CMRs - Cat. 1B; EC Annex VI Resp. Sens. - Cat. 1;Report - if used as a fragrance or flavor ingredient

Nickel hydroxide (Ni(OH)2) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Nickel hydroxide (Ni(OH)2) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 10-11-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/15359;Status: Cease Manufacture Update: 22-01-2013 https://echa.europa.eu/registration-dossier/-/registered-dossier/1686;Status: Cease Manufacture Update: 27-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/25346

Restricted substance: Nickel dihydroxide;EC: 235-008-5;Restriction condition document: PDF link

Atmospheric Standards · 1건

Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Nickel hydroxide is included on this list.

CERCLA Reportable Quantities · 1건

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 100 lb or 45.4 kg. The toll free number of the NRC is (800) 424-8802; In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).

Clean Water Act Requirements · 2건

Nickel hydroxide is designated as a hazardous substance under section 311(b)(2)(A) of the Federal Water Pollution Control Act and further regulated by the Clean Water Act Amendments of 1977 and 1978. These regulations apply to discharges of this substance. This designation includes any isomers and hydrates, as well as any solutions and mixtures containing this substance.

Toxic pollutant designated pursuant to section 307(a)(1) of the Clean Water Act and is subject to effluent limitations. /Nickel and compounds/

State Drinking Water Standards · 5건

(CA) CALIFORNIA 100 ug/L /Nickel/

(CT) CONNECTICUT 100 ug/L /Nickel/

(DE) DELEWARE 100 ug/L /Nickel/

(FL) FLORIDA 100 ug/L /Nickel/

(WI) WISCONSIN 100 ug/L /Nickel/

State Drinking Water Guidelines · 4건

(AZ) ARIZONA 150 ug/L /Nickel/

(MA) MASSACHUSETTS 100 ug/L /Nickel/

(ME) MAINE 140 ug/L /Nickel/

(MN) MINNESOTA 100 ug/L /Nickel/

안전 데이터

기존화학 물질
KE-25854
함량 및 규제정보
물질구분: 유독물질; 혼합물(제품)함량정보: 수산화 니켈[Nickel hydroxide; 12054-48-7, 11113-74-9] 및 이를 0.1% 이상 함유한 혼합물
유해화학물질 필터링
2019-1-943

화학 및 산업

약리 정보

Metabolism/Metabolites · 1건

Nickel is absorbed mainly through the lungs and gastrointestinal tract. Once in the body it enters the bloodstream, where it binds to albumin, L-histidine, and _2-macroglobulin. Nickel tends to accumulate in the lungs, thyroid, kidney, heart, and liver. Absorbed nickel is excreted in the urine, wherease unabsorbed nickel is excreted in the faeces. (L41)

용도 및 제조

Uses · 6건

Used to make nickel-cadmium batteries and catalysts; [HSDB]

Battery Manufacturing [Category: Industry]

Mfr of nickel salts

USED IN NICKEL-CADMIUM BATTERIES

HYDROGENATION OF FINELY POWDERED NEWSPAPER WITH NICKEL HYDROXIDE CATALYST PRODUCES CONVERSION IN HIGH YIELDS OF CELLULOSIC FEED MATERIALS TO LIQ HYDROCARBON FUELS.

CHEM INT FOR NICKEL CATALYSTS & NICKEL SALTS

U.S. Production · 2건

2023: 1,000,000 - <2,500,000 lb;2022: 1,000,000 - <5,000,000 lb;2021: 1,000,000 - <5,000,000 lb;2020: 1,000,000 - <5,000,000 lb

(1977) AT LEAST 6.45X10+7 G-INCL CAPTIVE PRODN

Consumer UsesCatalyst;Other
Industry UsesCatalyst;Intermediate;Other;Alloys;Conductive agent
Methods of Manufacturing · 5건

By adding a hypochlorite to a soln of nickelous salt.

... MAY BE PREPARED FROM SOLN OF NICKEL SALTS BY PRECIPITATION WITH ALKALINE HYDROXIDES, BUT PRODUCT IS USUALLY CONTAMINATED BY OCCLUDED OR ABSORBED FOREIGN SALTS. PURE NICKEL HYDROXIDE CAN BE PREPARED BY ELECTROLYTIC PRECIPITATION USING NICKEL ANODES (ANTONSEN & SPRINGER, 1967).

High purity crystalline nickel hydroxide can be made from nickel nitrate soln and potassium hydroxide by subsequent extraction of the gelatinous precipitate with hot alcohol.

Nickel sulfate treated with sodium hydroxide yields the gelatinous nickel hydroxide which, when neutralized, forms a fine precipitate that can be filtered

Industrial route for the manufacture of nickel hydroxide is by electro-deposition at an inert cathode using metallic nickel as the anode and nickel nitrate as the electrolyte

Household Products · 2건

Cosmetics product ingredient: Nickel hydroxide

Cosmetics product ingredient: Nickel dihydroxide (Nickel hydroxide)

공급사3 곳

陕西缔都新材料有限公司029-63373950 17392216152 · [email protected]
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.+8618950047208 · [email protected]
Hefei TNJ Chemical Industry Co.,Ltd.+86-0551-65418671 +86-189 4982 3763 · [email protected]

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