기본 정보
- CAS
30390-50-2- 표준 SMILES
CCCCCC=CCCC=O- InChIKey
CWRKZMLUDFBPAO-UHFFFAOYSA-N- 분자식
- C10H18O
- 평균 분자량
- 154.25 g/mol
- 단동위원소 질량
- 154.13576519
개요
4-Decenal has been reported in Porophyllum ruderale with data available.
이름 및 식별자
- 우선 이름
- 4-Decenal
- IUPAC
- dec-4-enal
- 영어명
- DECENAL
- 분자식
- C10H18O
- 분자량
- 154.25
이름 및 동의어
4-Decenal30390-50-2DTXSID0067555RefChem:1070565DTXCID8038190641-403-74-decen-1-al(E)-4-decen-1-alSCHEMBL1626855SCHEMBL7296514AKOS028109351DB-045659
이름 더 보기
4-Decene-1-al
DB-054810
데이터베이스 식별자
- CAS
30390-50-2- PubChem CID
- 61875
- DTXSID
DTXSID0067555- EC Number
- 641-403-7
물성
구조 계산 물성
- XLogP
- 3.1
- 극성 표면적
- 17.1 Ų
- 수소 결합 공여자 수
- 0
- 수소 결합 수용자 수
- 1
- 회전 가능 결합 수
- 7
- 무거운 원자 수
- 11
- 형식 전하
- 0
- 복잡도
- 105
실험 및 물리화학적 성질
Food AdditivesFLAVORING AGENT OR ADJUVANT -> FDA Substance added to food
Density0.843-0.850
Flavoring AgentsEU Flavoring substances
Solubility
soluble in alcohol and most fixed oils; insoluble in water
(in ethanol)
Boiling Point78-80 °C (10 mm Hg)
Refractive Index1.442-1.447
Physical Descriptioncolourless to slightly yellow liquid with an orange-like, fatty odour
물리화학적 성질
- 녹는점
- -16 °C · -16°C (estimate)
- 끓는 점
- 200 ℃ · 200℃
- 밀도
- 0.835 · 0.835
- 굴절률
- 1.445 · 1.4450
- FEMA
- 3264 · 3264 | 4-DECENAL
- 인화점
- 81 ℃ · 81℃
- 냄새
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 100% (138 of 138) of all reports.
Not Classified
Aggregated GHS information provided per 138 reports by companies from 1 notifications to the ECHA C&L Inventory.
유해성 정보
Regulatory Information
Chemical: 4-Decenal
4-Decenal: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - 4-Decenal: Human health tier I assessment
Hazard Classes and CategoriesNot Classified
독성 정보
TreatmentKidney dialysis is usually needed to relieve the symptoms of uremic syndrome until normal kidney function can be restored.
Health EffectsChronic exposure to uremic toxins can lead to a number of conditions including renal damage, chronic kidney disease and cardiovascular disease.
Exposure RoutesEndogenous, Ingestion, Dermal (contact)
Toxicity Summary
Uremic toxins such as 4-Decenal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulate the production of reactive oxygen species. This seems to be mediated by the direct binding or inhibition by uremic toxins of the enzyme NADPH oxidase (especially NOX4 which is abundant in the kidneys and heart) (A7868). Reactive oxygen species can induce several different DNA methyltransferases (DNMTs) which are involved in the silencing of a protein known as KLOTHO. KLOTHO has been identified as having important roles in anti-aging, mineral metabolism, and vitamin D metabolism. A number of studies have indicated that KLOTHO mRNA and protein levels are reduced during acute or chronic kidney diseases in response to high local levels of reactive oxygen species (A7869).
화학 및 산업
약리 정보
Metabolism/MetabolitesUremic toxins tend to accumulate in the blood either through dietary excess or through poor filtration by the kidneys. Most uremic toxins are metabolic waste products and are normally excreted in the urine or feces.
용도 및 제조
UsesNaturally produced by the body (endogenous).
Use Classification
Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes
Flavoring Agents -> JECFA Flavorings Index
General Manufacturing Information4-Decenal: ACTIVE
응용 분야
출처Reported formed in the auto-oxidation of lipids, grilled beef and soybeans
제조 방법
From 1-octen-3-ol and vinyl ethyl ether in the presence of p-methylbenzene sulfonic acid.
공급사8 곳
Hebei Zhuanglai Chemical Trading Co Ltd+86-16264648883 · [email protected]
北京安司莫森技术有限公司010-82954736 13391601435 · [email protected]
北京东华力拓科技发展有限公司010-88425576 · [email protected]
上海钰康生物科技有限公司+86-18930848214 +86-021-56762820 · [email protected]
관련 반응
1건
화합물 노트
불러오는 중…