Tobramycin Sulphate Salt

Tobramycin sulfate · TOBRAMYCIN SULPHATE · obracine · tenemicin · TOBRAMYCIN SLIPHATE · TobraMycin Sulfate API · 1-epitobramycinsulfate · TOBRAMYCIN SULFATE SALT

https://huagongshe.com/ko/chemical/62005

식별자 및 물리적 특성

CAS No.	49842-07-1
분자식	C18H39N5O13S
평균 분자량	565.6 g/mol
SMILES	NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O.O=S(=O)(O)O
InChIKey	ZEUUPKVZFKBXPW-TWDWGCDDSA-N
PubChem CID	62005
ChEMBL	CHEMBL1200780

화학 및 물리적 성질

극성 표면적	351
수소 결합 공여자 수	12
수소 결합 수용자 수	18
회전 가능 결합 수	6
무거운 원자 수	37
형식 전하	0
복잡도	690
저장 조건	2-8°C
용해도	메탄올(약간), 물(적당)에 용해됨
물리적 상태	가루
색상	White to off-white
용해도	물에 용해됩니다(50mg/ml).
안정성	흡습성
InChIKey	ZEUUPKVZFKBXPW-SYOBZNKXNA-N
SMILES	OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O
EPA	Tobramycin sulfate (49842-07-1)

안전 및 규제

수질 위해 등급(WGK)	3
관세 코드	2941900000
위험 문구(R)	61-20/21/22
위험 표시	T
안전 문구(S)	53-22-36/37/39-45
위험 등급	Acute Tox. 4 DermalAcute Tox. 4 InhalationRepr. 1B
저장 분류	6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects

용도

Tobramycin sulfate is used as an antibiotic which is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas. It is used to inhibit bacterial protein synthesis at the level of 30S (16S rRNA) and 70S ribosomal complex assembly. It is used to treat pseudomonas aeruginosa lung infections and is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis and other soft-tissue infections. It is a potential therapy for sinus infections1. Product T1783 has been used to study antibiotic resistance2.