Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
염화콜린
염화콜린 · 트리메틸(2-하이드록시에틸)암모늄클로라이드 · 콜린 · 콜린클로라이드 · 2-하이드록시-N,N,N-트리메틸-에탄아미늄클로라이드 · 빌리뉴린클로 · 2-하이드록시-N,N,N-트라이메틸에탄아미늄염화물 · 콜린염및에스터(예:콜린클로라이드)
식별자 및 물리적 특성
| CAS No. | 67-48-1 |
|---|---|
| 분자식 | C5H14NO.Cl |
| 평균 분자량 | 139.62 g/mol |
| SMILES | C[N+](C)(C)CCO.[Cl-] |
| InChIKey | SGMZJAMFUVOLNK-UHFFFAOYSA-M |
| PubChem CID | 6209 |
| ChEMBL | CHEMBL282468 |
| ChEBI | CHEBI:133341 |
| EC No. | 200-655-4 |
| DTXSID | DTXSID4020325 |
| 현지명 | 염화콜린 |
화학 및 물리적 성질
| 극성 표면적 | 20.2 |
|---|---|
| 수소 결합 공여자 수 | 1 |
| 수소 결합 수용자 수 | 2 |
| 회전 가능 결합 수 | 2 |
| 무거운 원자 수 | 8 |
| 형식 전하 | 0 |
| 복잡도 | 46.5 |
| 화장품 | Cosmetic ingredients (Choline Chloride) -> CIR (Cosmetic Ingredient Review) |
| pH | 4.7 (10% SOLN IN WATER)5.0-7.5 (25℃, 1M in H2O) |
| 농약 | RodenticidesActive substance -> EU Pesticides database: Not approved |
| LogP(분배 계수) | -5.16 |
| 식품 첨가물 | NUTRIENT SUPPLEMENT -> FDA Substance added to food |
| Color/Form | WHITE CRYSTALSDeliquescent crystals |
| 용해도 | Very soluble (NTP, 1992)Very sol in water and alcoholSolubility in water: miscibleSoluble in waterSoluble (in ethanol)H2O: 1 M, 투명, 무색 |
| Decomposition | When heated to decomposition it emits toxic fumes of chloride, /sulfur oxides/, and /Nitrogen oxides/. |
| 녹는점 | 577 to 581 °F (Decomposes) (NTP, 1992)305 °C (decomposes)302-305 °C (dec.) (lit.) |
| Physical Description | Choline chloride appears as white crystals. Practically neutral aqueous solution. (NTP, 1992)Dry PowderLiquidWHITE HYGROSCOPIC CRYSTALS.Colourless or white crystals, also in the form of white crystalline solid |
| Stability/Shelf Life | Keep tightly closed. |
| Collision Cross Section | 121 Ų [M]+ [CCS Type: TWMethod: calibrated with polyalanine and drug standards] |
| 밀도 | 1.0238 (rough estimate) |
| 굴절률 | 1.5400 (estimate) |
| FEMA | 4500 | Choline chloride (Also Includes Choline) |
| 저장 조건 | Sealed in dry,Room Temperature |
| 물리적 상태 | 결정체 |
| 색상 | 하얀색 |
| 냄새 | 희미하고 트리메틸아민 냄새 |
| 생물학적 소스 | synthetic (organic) |
| 용해도 | 녹는 |
| Merck | 14,2206 |
| JECFA Number | 2003 |
| BRN | 3563126 |
| 안정성 | 안정적인. 강한 산화제, 습기와 호환되지 않습니다. 건조한 환경에서 보관하십시오. |
| 화장품 원료 기능 | 피부 컨디셔닝보습제 |
| InChI | 1S/C5H14NO.ClH/c1-6(2,3)4-5-7/h7H,4-5H2,1-3H31H/q+1/p-1 |
| InChIKey | SGMZJAMFUVOLNK-UHFFFAOYSA-M |
| SMILES | [Cl-].C[N+](C)(C)CCO |
| LogP(분배 계수) | -3.70 |
| NIST | Choline chloride(67-48-1) |
| EPA | Choline chloride (67-48-1) |
화학적 성질
White crystalline powder
안전 및 규제
| GHS 분류 | This chemical does not meet GHS hazard criteria for 53.5% (236 of 441) of all reports.WarningH315 (46%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 441 reports by companies from 18 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 규제 정보 | Chemical: Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, chlorideDirective (EC) No 46/2002Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, chloride (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, chloride (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)2004/129/ECStatus: Active Update: 20-09-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/5360Choline chloride: Does not have an individual approval but may be used under an appropriate group standard |
| 기타 안전 정보 | IMAP assessments - Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, chloride: Environment tier I assessment |
| 화재 위험 | This chemical is relatively nonflammable. (NTP, 1992)Combustible. Gives off irritating or toxic fumes (or gases) in a fire. |
| FDA 요건 | Choline chloride used as a nutrient in food for human consumption is generally recognized as safe when used in accordance with good manufacturing practice.Choline chloride used as a nutrient and/or dietary supplement in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice. |
| 반응성 그룹 | Alcohols and Polyols |
| Special Reports | National Academy of Sciences. Institute of Medicine. Food and Nutrition Board. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (1998). Available from: http://www.nal.usda.gov/fnic/DRI//DRI_Thiamin/390-422_150.pdf as of February 28, 2008. |
용도
개요
흰색 과립.
용도
급식 부식방지제, 건강한 & 성장을 승진시키십시오, 영양을 승진시키십시오.
일반 설명
Choline chloride appears as white crystals. Practically neutral aqueous solution(NTP, 1992). It is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.