Triamcinolone Diacetate

TAC-D · 8357RP · CINO-40 · Tedarol · Cenacort · Tracilon · Kenacourt · 21-diacetate

식별자 및 물리적 특성

CAS No.	67-78-7
분자식	C25H31FO8
평균 분자량	478.5 g/mol
단동위원소 질량	478.2002961 g/mol
SMILES	CC(=O)OCC(=O)[C@@]1(O)[C@H](OC(C)=O)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
InChIKey	XGMPVBXKDAHORN-RBWIMXSLSA-N
PubChem CID	6216
ChEMBL	CHEMBL1200449
ChEBI	CHEBI:9669
EC No.	200-669-0
DTXSID	DTXSID0048713

XLogP	1.9
극성 표면적	127
수소 결합 공여자 수	2
수소 결합 수용자 수	9
회전 가능 결합 수	6
무거운 원자 수	34
형식 전하	0
복잡도	1,020
LogP(분배 계수)	1.92
Human Drugs	FDA approved drugs -> Active ingredientPharmaceuticals
Collision Cross Section	209.5 Å² [M+H]+ [CCS Type: TWMethod: calibrated with polyalanine and drug standards]
녹는점	186-188 C
끓는 점	608.5±55.0 °C(Predicted)
밀도	1.2087 (estimate)
저장 조건	Refrigerator
용해도	Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
pKa(산도 계수)	11.21±0.70(Predicted)
물리적 상태	고체
색상	하얀색
용해도	48mg/L(25℃)
NIST	Triamcinolone diacetate(67-78-7)
EPA	Triamcinolone diacetate (67-78-7)

White Solid

GHS 분류	DangerH301 (25%): Toxic if swallowed [Danger Acute toxicity, oral]P203, P261, P264, P270, P271, P280, P301+P316, P301+P317, P302+P352, P304+P340, P317, P318, P321, P330, P362+P364, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 4 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
기타 안전 정보	IMAP assessments - Pregna-1,4-diene-3,20-dione, 16,21-bis(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11.beta.,16.alpha.)-: Environment tier I assessment
Hazard Classes and Categories	Acute Tox. 4 (25%)
수질 위해 등급(WGK)	3
관세 코드	2937220000

A glucocorticoid that inhibits prolyl hydroxylase activity, Triamcinolone diacetate can be used as an antiasthmatic and antiallergic drug.