3,3'-디메톡시벤지딘 디수화염화물
3,3'-디메톡시벤지딘디수화염화물 · 3,3`-디메톡시-[1,1-비페닐]-4,4`-디아민염산염(1:2) · 3,3`-디메톡시-[1,1-비페닐]- 4,4`-디아민 염산염(1:2) · 3,3'-다이메톡시-[1,1'-바이페닐]-4,4'-다이아민 염산염 (1:2) · 3,3'-다이메톡시-[1,1'-바이페닐]-4,4'-다이아민 이염산염 · 3,3'-다이메톡시벤지딘 이염산염 · o-다이아니시딘 이염산염 · 이염화 3,3'-다이메톡시바이페닐-4,4'-일렌 다이암모늄
식별자 및 물리적 특성
| CAS No. | 20325-40-0 |
|---|---|
| 분자식 | C14H16N2O2.2HCl |
| 평균 분자량 | 317.2 g/mol |
| 단동위원소 질량 | 316.07453318 g/mol |
| SMILES | COc1cc(-c2ccc(N)c(OC)c2)ccc1N.Cl.Cl |
| InChIKey | UXTIAFYTYOEQHV-UHFFFAOYSA-N |
| PubChem CID | 62311 |
| ChEMBL | CHEMBL1868992 |
| EC No. | 243-737-5 |
| DTXSID | DTXSID1020485 |
| 현지명 | 3,3'-디메톡시벤지딘 디수화염화물 |
화학 및 물리적 성질
| 극성 표면적 | 70.5 |
|---|---|
| 수소 결합 공여자 수 | 4 |
| 수소 결합 수용자 수 | 4 |
| 회전 가능 결합 수 | 3 |
| 무거운 원자 수 | 20 |
| 형식 전하 | 0 |
| 복잡도 | 236 |
| 용해도 | 10 to 50 mg/mL at 68 °F (NTP, 1992)H2O: 용해성25mg/mL |
| 녹는점 | 514 °F (NTP, 1992)137 °C268 °C |
| 증기압 | 0.0000000088 [mm Hg] @25 °C |
| Physical Description | 3,3'-dimethoxybenzidine dihydrochloride is an off-white powder. (NTP, 1992)Wet SolidCBI |
| 인화점 | 206℃ |
| 저장 조건 | 2-8°C |
| 물리적 상태 | 태블릿 형태 |
| 색상 | 연한 베이지~보라색~회색 |
| pH | 1.7 at 20℃ and 100g/L |
| 용해도 | 20°C에서 1~5g/100mL |
| BRN | 3917996 |
| 주요 응용 | 진단 검사 제조혈액학조직학 |
| InChI | InChI=1S/C14H16N2O2.ClH/c1-17-13-7-9(3-5-11(13)15)10-4-6-12(16)14(8-10)18-2/h3-8H,15-16H2,1-2H31H |
| InChIKey | UXTIAFYTYOEQHV-UHFFFAOYSA-N |
| SMILES | O(C1=C(C=CC(C2C=CC(N)=C(OC)C=2)=C1)N)C.Cl |
| EPA | 3,3'-Dimethoxybenzidine dihydrochloride (20325-40-0) |
화학적 성질
Off-white or grey tablets
안전 및 규제
| GHS 분류 | DangerH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P203, P260, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P318, P321, P330, P363, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 52 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Not Classified |
|---|---|
| 규제 정보 | Hazard Traits - Carcinogenicity[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dimethoxy-, hydrochloride (1:2) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of [1,1'-Biphenyl]-4,4'-diamine, 3,3'-dimethoxy-, hydrochloride (1:2) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 04-01-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/16226[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dimethoxy-, dihydrochloride: Does not have an individual approval but may be used under an appropriate group standard |
| 화재 위험 | Flash point data are not available for this chemical, but it is probably combustible. (NTP, 1992) |
| 반응성 그룹 | Ethers |
| Reactivity Profile | 3,3'-DIMETHOXYBENZIDINE DIHYDROCHLORIDE is an ether substituted acidic organic salt. Reacts weakly as a acid to neutralize bases. May react with strong oxidizing agents or strong reducing agents. |
| Air and Water Reactions | Water soluble. |
| Hazard Classes and Categories | Acute Tox. 4 (100%) |
| 소화 | Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992) |
| 응급 처치 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
용도
개요
o-Dianisidine (dihydrochloride) is a colorimetric peroxidase substrate that has been used as a substrate to semi-quantitatively measure lactate, uric acid , and glucose. It has also been used as a reagent for the detection of various metals, thiocyanates, and nitrites. This aromatic amine is initially colorless but turns to violet upon oxidization and is spectrophotometrically measured at a wavelength of 405 nm.
용도
It is suitable for use in ELISA procedures. In neurohistochemistry o-Dianisidine dihydrochloride has demonstrated perikaryal labeling as well as retrograde and anterograde transport to the primary olfactory cortex. It has also been used for a paper based-micro fluidic device to semi-quantitatively measure lactate, uric acid, and glucose. 3,3'-Dimethoxybenzidine is used principally as an intermediate in the production of commercial bisazobiphenyl dyes for coloring textiles, paper, plastic, rubber, and leather.
일반 설명
Off-white powder.