3-(Trimethoxysilyl)propyl chloride (HCID 62449)

이름 및 식별자

우선 이름: 3-(Trimethoxysilyl)propyl chloride
IUPAC: 3-chloropropyl(trimethoxy)silane
현지명: (3-클로로프로필)트리메톡시실란
영어명: 3-Chloropropyltrimethoxysilane
분자식: C6H15ClO3Si
분자량: 198.72

이름 및 동의어

3-Chloropropyltrimethoxysilane2530-87-2(3-Chloropropyl)trimethoxysilaneSilane, (3-chloropropyl)trimethoxy-3-(Trimethoxysilyl)propyl chlorideKBM 703A 143SH 6076Z 6076T21BNL1S7FDTXSID4027490NSC-83878

이름 더 보기

(3-클로로프로필)트라이메톡시실레인(3-클로로프로필)트라이메톡시실란(3-클로로프로필)트리메톡시실란클로르프로필-3트리메톡시실란(3-클로로프로필)트라이메톡시실란((3-CHLOROPROPYL)TRIMETHOXYSILANE)(감마-클로로프로필)트라이메톡시실란3-(트라이메톡시실란)-프로필3-클로로프로필트라이메톡시실란A-143Dynasylan CPTMOSilquest A-143감마-클로로프로필트라이메톡시실란실란 (3-클로로프로필)트리스(메톡시)-실란, (3-클로로프로필)트라이메톡시-ChloropropyltrimethoxysilaneCPTMODC Z-6076a143z6076DK702CC3300

DTXCID207490CPTMS cpdRefChem:400119219-787-93-chloropropyl(trimethoxy)silaneCPS-MSila-Ace S 6203-Chloropropyltrimethyoxysilane

데이터베이스 식별자

CAS: 2530-87-2
PubChem CID: 62449
DTXSID: DTXSID4027490
ChEMBL: CHEMBL3184213
UNII: T21BNL1S7F
EC Number: 219-787-9
Nikkaji: J121.171D

물성

구조 계산 물성

극성 표면적: 27.7 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 3
회전 가능 결합 수: 6
무거운 원자 수: 11
형식 전하: 0
복잡도: 89

실험 및 물리화학적 성질

Density1.09 @25 °C

Boiling Point195 °C @760 [mm Hg]

Vapor Pressure0.39 [mmHg]

Physical Description · 2건

Liquid

Liquid; [Reference #1] Colorless liquid; [Alfa Aesar MSDS]

물리화학적 성질

녹는점: -50 °C · -50°C
끓는 점: 195 °C750 · 195 °C750 mm Hg(lit.)
밀도: 1.09 g/mL · 1.09 g/mL at 25 °C(lit.)
증기압: 5 hPa · <5 hPa (20 °C)
굴절률: 20 · n20/D 1.419(lit.)
인화점: 136 °F · 136 °F
저장 조건: 30 °C · Store below +30°C.
용해도: 유기용매와 섞일 수 있음.
물리적 상태: 액체
산도 계수 (pKa): 10 · 10[at 20 ℃]
색상: 무색투명~미황색
Specific Gravity: 1.077 · 1.077
폭발한계: 5.5 · 5.5-44%(V)
수용성: 물에서 가수분해됩니다.
BRN: 969627 · 969627
안정성: 안정적이지만 공기와 습기에 민감합니다. 물, 습기, 강산화제, 공기와 혼합되지 않습니다. 불활성이고 건조한 분위기에 보관하십시오.
InChI: 1S/C6H15ClO3Si/c1-8-11(9-2,10-3)6-4-5-7/h4-6H2,1-3H3
InChIKey: OXYZDRAJMHGSMW-UHFFFAOYSA-N
SMILES: CO[Si](CCCCl)(OC)OC
LogP: -1.1 · -1.1-2 at 20℃
NIST: Silane, (3-chloropropyl)trimethoxy-(2530-87-2)
EPA: (3-Chloropropyl)trimethoxysilane (2530-87-2)

화학적 성질

Colorless transparent liquid

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 83.4% (181 of 217) of all reports.

Warning

H226 (11.5%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 217 reports by companies from 8 notifications to the ECHA C&L Inventory.；Reported as not meeting GHS hazard criteria per 181 of 217 reports by companies.；There are 5 notifications provided by 36 of 217 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 4건

Chemical: Silane, (3-chloropropyl)trimethoxy-

Silane, (3-chloropropyl)trimethoxy- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Silane, (3-chloropropyl)trimethoxy- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 03-05-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/16008；Status: Active Update: 21-06-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/33821

3-(Chloropropyl)-trimethoxysilane: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationEvaluation - Chemicals that are unlikely to require further regulation to manage risks to environment

Hazards Summary · 1건

Rapidly hydrolyzed producing 3 moles of methanol for every mole of silanetriol; Methanol is expected to cause any toxicity observed; Not a skin sensitizer in guinea pigs; A repeated-dose inhalation study produced no adverse effects at concentrations up to 100 ppm; Clinical observations in a micronucleus assay of mice include ataxia, tremors, prostration, myoclonic jerks, and vocalization; No reproductive or developmental toxicity observed in an inhalation study of rats at concentrations up to 100 ppm; [Reference #1] Reacts with water evolving methanol; A skin and strong eye irritant; [Alfa Aesar MSDS] See Methyl alcohol. See Trimethoxypropylsilane.

Hazard Classes and Categories · 2건

Flam. Liq. 3 (11.5%)

Flammable liquids - Category 3；Skin corrosion/irritation - Category 2；Serious eye damage/eye irritation - Category 2B；Specific target organ toxicity - Single exposure - Category 3 (Narcotic effects)；Specific target organ toxicity - Repeated exposure - Category 2 (urinary bladder)

안전 및 보호

Protective Action Criteria (PAC) · 3건

20 [mg/m3]

220 [mg/m3]

1300 [mg/m3]

독성 정보

Adverse EffectsNeurotoxin - Other CNS neurotoxin

규제 정보

Regulatory Information · 4건

Chemical: Silane, (3-chloropropyl)trimethoxy-

Silane, (3-chloropropyl)trimethoxy- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Silane, (3-chloropropyl)trimethoxy- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 03-05-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/16008；Status: Active Update: 21-06-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/33821

3-(Chloropropyl)-trimethoxysilane: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk: 1
tsca: TSCA listed
rtecs: VV2680000
ridadr: UN 1993 3/PG 3
독성: LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit 3062 mg/kg
HS 번호: 29310095
risk_code: 36/37/38
hazard_code: Xi
safety_code: 26-36-37/39
포장분류: III
위험 등급: 8
기존화학 물질: KE-05889
자연 발화 온도: 220 °C
스토리지 클래스: 10 - Combustible liquids

화학 및 산업

용도 및 제조

UsesUsed as a coupling agent for filled composites and industrial goods (textile goods); Used in closed systems to prevent loss due to rapid hydrolysis; [Reference #1]

U.S. Production2023: 1,000,000 - <5,000,000 lb；2022: 2,500,000 - <4,000,000 lb；2021: 2,500,000 - <4,000,000 lb；2020: 2,500,000 - <4,000,000 lb

Industry UsesIntermediate；Hardener；Adhesion/cohesion promoter；Monomers

General Manufacturing Information · 2건

All Other Basic Inorganic Chemical Manufacturing；Synthetic Rubber Manufacturing；All Other Chemical Product and Preparation Manufacturing；Paint and Coating Manufacturing；All Other Basic Organic Chemical Manufacturing

Silane, (3-chloropropyl)trimethoxy-: ACTIVE

응용 분야 · 3건

개요(3-Chloropropyl)trimethoxysilane is a silane coupling agent that is commonly used in the field of chemistry. It is a colorless and transparent liquid that has a strong odor. It is used as a coupling agent in the polymer industry to improve the adhesion between two substrates. It is also a starting material for synthesizing various compounds, such as surfactants, organosilanes, and other functional molecules.

용도(3-Chloropropyl)trimethoxysilane is a good coupling agent for epoxy resins to glass in laminates.

일반 설명(3-Chloropropyl)trimethoxysilane (CPTMS) is an organo-silane which forms a self-assembled monolayer (SAMs) that facilitates the surface modification of different bio-and nano- materials.