브롬화테트라에틸암모늄
브롬화테트라에틸암모늄 · 테트라에틸암모늄브롬화물 · 테트라에틸암모늄브로마이드 · 테트릴암모늄브로마이드 · TEAB · Bromethyl · tetraethylazanium bromide · Tetra ethyl ammonium bromide Solid
식별자 및 물리적 특성
| CAS No. | 71-91-0 |
|---|---|
| 분자식 | C8H20N.Br |
| 평균 분자량 | 210.16 g/mol |
| 단동위원소 질량 | 209.07791174 g/mol |
| SMILES | CC[N+](CC)(CC)CC.[Br-] |
| InChIKey | HWCKGOZZJDHMNC-UHFFFAOYSA-M |
| PubChem CID | 6285 |
| ChEMBL | CHEMBL324254 |
| EC No. | 200-769-4 |
| DTXSID | DTXSID9044457 |
| 현지명 | 브롬화테트라에틸암모늄 |
화학 및 물리적 성질
| 극성 표면적 | 0 |
|---|---|
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 4 |
| 무거운 원자 수 | 10 |
| 형식 전하 | 0 |
| 복잡도 | 47.5 |
| 물질 분류 | Nitrogen Compounds -> Quaternary Amines |
| 밀도 | 1.39 @ 20°C1,397 g/cm3 |
| 증기압 | 0.00000079 [mmHg]<1 hPa |
| Physical Description | LiquidDeliquescent solid[Merck Index] Colorless crystalline solidHighly hygroscopic[Sigma-Aldrich MSDS] |
| 녹는점 | 285 °C (dec.)(lit.) |
| 끓는 점 | >310 °C/979.1 hPa |
| 증기 밀도 | 5.3 (vs air) |
| 굴절률 | 1,442-1,444 |
| 저장 조건 | Store below +30°C. |
| 용해도 | 아세토니트릴: 0.1 g/mL 따뜻하고 투명하며 무색 |
| 물리적 상태 | 액체 |
| 색상 | 흰색에서 크림색으로 |
| 냄새 | 냄새 없는 |
| pH | 6.5 (100g/l, H2O, 20℃) |
| 용해도 | 2795g/L(25℃) |
| Merck | 14,9199 |
| BRN | 3563430 |
| 안정성 | 안정적인. 강한 산화제와 호환되지 않습니다. |
| InChI | 1S/C8H20N.BrH/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H31H/q+1/p-1 |
| InChIKey | HWCKGOZZJDHMNC-UHFFFAOYSA-M |
| SMILES | [Br-].CC[N+](CC)(CC)CC |
| NIST | Tetraethylammonium bromide(71-91-0) |
| EPA | Ethanaminium, N,N,N-triethyl-, bromide (71-91-0) |
화학적 성질
white to light yellow crystalline solid
안전 및 규제
| GHS 분류 | This chemical does not meet GHS hazard criteria for 1.6% (5 of 317) of reports.WarningH302 (18.3%): Harmful if swallowed [Warning Acute toxicity, oral]P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 317 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 규제 정보 | Chemical: Ethanaminium, N,N,N-triethyl-, bromideEthanaminium, N,N,N-triethyl-, bromide (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanaminium, N,N,N-triethyl-, bromide (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 23-04-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/19226Tetraethylammonium bromide: HSNO Approval: HSR006306 Approved with controls |
| 기타 안전 정보 | IMAP assessments - Tetraethylammonium salts: Human health tier II assessment |
| 유해성 요약 | Causes mydriasis, tremor, and changes in motor activity in acute intraperitoneal studies of miceCauses ganglion blockage and lowered blood pressure in acute intravenous studies of cats[RTECS] A skin and strong eye irritantTargets the heart and CNS[Sigma-Aldrich MSDS] |
| Hazard Classes and Categories | Acute Tox. 4 (18.3%)Eye irritation - category 2B |
| Protective Action Criteria (PAC) | 8.4 [mg/m3]92 [mg/m3]550 [mg/m3] |
| 수질 위해 등급(WGK) | 3 |
| TSCA 등재 상태 | TSCA listed |
| RTECS 번호 | BS5950000 |
| 관세 코드 | 29239000 |
| 위험 문구(R) | 36/37/38 |
| 위험 표시 | Xi |
| 안전 문구(S) | 26-36-37/39 |
| 기존화학 물질 | KE-34221 |
| F 고인화성물질 | 3 |
| 위험 등급 | Aquatic Chronic 3 |
| 저장 분류 | 11 - Combustible Solids |
용도
용도
Tetraethylammonium Bromide, can be used as a source of tetraethylammonium ions for various pharmaceutical studies. It has also the ability to block K+ channels in various tissues.
일반 설명
The use of ion-pairing reagents as mobile phase additives allows the separation of ionic and highly polar substances on reversed phase HPLC columns. The purity of mobile phase additives is of utmost importance to their successful application. Sigma-Aldrich offers an outstanding range of tailor-made reagents for anionic (quaternary ammonium and phosphonium salts) and cationic (alkanesulfonates) determination. All mobile phase additives are subject to rigorous testing with special emphasis on the requirements of modern reversed phase HPLC: