Deferoxamine Hydrochloride

HCID 62880
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기본 정보

CAS
1950-39-6
표준 SMILES
CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN.Cl
InChIKey
KCRQZLMAZHZDCL-UHFFFAOYSA-N
분자식
C25H49ClN6O8
평균 분자량
597.1 g/mol
단동위원소 질량
596.3300402

개요

Deferoxamine Hydrochloride is the hydrochloride salt form of deferoxamine, an iron chelating agent. Deferoxamine chelates iron from intra-lysosomal ferritin and hemosiderin forming ferrioxamine, a water-soluble chelate excreted by the kidneys and in the feces via the bile. This agent does not readily bind iron from transferrin, hemoglobin, myoglobin or cytochrome. (NCI)

이름 및 식별자

우선 이름
Deferoxamine Hydrochloride
IUPAC
N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide;hydrochloride
영어명
N'-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxysuccinamide monohydrochloride
분자식
C25H49ClN6O8
분자량
597.14496

이름 및 동의어

Deferoxamine hydrochlorideDeferoxamine HCl1950-39-6Deferoxamine hydrochloride [USAN]Ba-29837G9VYJ96FOJDesferrioxamine hydrochlorideEINECS 217-767-4Ba 29837NSC-268993DTXSID50173157Deferoxamine hydrochloride (USAN)
이름 더 보기
Butanediamide,N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-(5-aminopentyl)-N1-hydroxy-,hydrochloride (1:1)
DEFEROXAMINE HYDROCHLORIDE [MI]NSC 268993DEFEROXAMINE HYDROCHLORIDE [WHO-DD]NSC268993N'-(5-((4-((5-(Acetylhydroxyamino)pentyl)amino)-1,4-dioxobutyl)hydroxyamino)pentyl)-N-(5-aminopentyl)-N-hydroxysuccinamide monohydrochlorideN'-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxysuccinamide monohydrochlorideN-(5-{3-((5-Aminopentyl)hydroxycarbamoyl)propionamido}pentyl)-3-{(5-(N-hydroxyacetamido)pentyl)carbamoyl}propionohydroxamic acid monohydrochlorideN-(5-(3-((5-AMINOPENTYL)HYDROXYCARBAMOYL)PROPIONAMIDO)PENTYL)-3-((5-(N-HYDROXYACETAMIDO)PENTYL)CARBAMOYL)PROPIONOHYDROXAMIC ACID MONOHYDROCHLORIDE

데이터베이스 식별자

CAS
1950-39-6
PubChem CID
62880
DTXSID
DTXSID50173157
ChEMBL
CHEMBL2002581
UNII
G9VYJ96FOJ
EC Number
217-767-4

물성

구조 계산 물성

극성 표면적
206 Ų
수소 결합 공여자 수
7
수소 결합 수용자 수
9
회전 가능 결합 수
23
무거운 원자 수
40

물리화학적 성질

녹는점
172 · 172-175°

안전 및 규제

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 33.3% (1 of 3) of reports.

Danger

H315 (66.7%): Causes skin irritation [Warning Skin corrosion/irritation]

P233, P260, P261, P264, P264+P265, P271, P272, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 3 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory InformationREACH registered substance: N'-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxysuccinamide monohydrochloride (EC: 217-767-4)
Hazard Classes and CategoriesSkin Irrit. 2 (66.7%)

안전 데이터

신호 어
Danger
유해·위험 문구
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드 H315

화학 및 산업

공급사3 곳

陕西缔都医药化工有限公司029-029-81120477 17792793610 · [email protected]
北京泰和景明医药科技有限公司15011440205 · [email protected]
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.+8618950047208 · [email protected]

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