기본 정보
- 표준 SMILES
CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccccc3)[C@H]2SC1.Cl.O- InChIKey
YHJDZIQOCSDIQU-OEDJVVDHSA-N- 분자식
- C16H20ClN3O5S
- 평균 분자량
- 401.9 g/mol
- 단동위원소 질량
- 401.08121942
개요
Cephalexin Hydrochloride is the hydrochloride salt form of cephalexin, a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalexin hydrochloride binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
이름 및 식별자
- 우선 이름
- Cephalexin Hydrochloride
- IUPAC
- (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate;hydrochloride
- 현지명
- 세팔렉신일염산염
- 영어명
- Cephalexin monohydrochloride
- 분자식
- C16H17N3O4S.ClH.H2O
- 분자량
- 401.87
이름 및 동의어
Cephalexin hydrochlorideCephalexin HClKeftab105879-42-3Cefalexin hydrochlorideLY0611886VJE5G3D98LY-061188RefChem:57269Cephalexin Monohydrochloride7-(D-2-Amino-2-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid hydrochloride monohydrateCephalexin (hydrochloride monohydrate)
이름 더 보기
세팔렉신일염산염cephalexin hydrochloride monohydrate5-Thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 7-(2R)-aminophenylacetylamino-3-methyl-8-oxo-, monohydrochloride, monohydrate, (6R,7R)-
(6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate;hydrochlorideCephalexin monohydrochloride monohydrateKeftab (TN)(6R,7R)-7-((2R)-2-Amino-2-phenylacetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, monohydrochloride, monohydrateCephalexin hydrochloride [USAN]UNII-6VJE5G3D98(6R,7R)-7-[(2R)-2-Amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monohydrochloride, monohydrateCephalexin hydrochloride [USAN:USP]
데이터베이스 식별자
- CAS
105879-42-3- PubChem CID
- 62979
- DTXSID
DTXSID10909777- ChEMBL
CHEMBL1200366- UNII
- 6VJE5G3D98
물성
구조 계산 물성
- 극성 표면적
- 139 Ų
- 수소 결합 공여자 수
- 5
- 수소 결합 수용자 수
- 7
- 회전 가능 결합 수
- 4
- 무거운 원자 수
- 26
- 형식 전하
- 0
- 복잡도
- 600
실험 및 물리화학적 성질
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
안전 및 규제
유해성 정보
Regulatory Information
5-Thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 7-(2R)-aminophenylacetylamino-3-methyl-8-oxo-, monohydrochloride, monohydrate, (6R,7R)-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
화학 및 산업
약리 정보
MeSH Pharmacological ClassificationSubstances that inhibit the growth or reproduction of BACTERIA.
응용 분야
용도Antibacterial.
공급사1 곳
陕西缔都医药化工有限公司029-81024372 17792795018 · [email protected]
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