홈MCP워크벤치Skills
홈워크벤치알림마이페이지
Huagongshe 오픈 프로젝트:[email protected]AI 접속: llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.7.8
  1. 홈
  2. /화합물

셀레노시스테인

Seleno-(DL)-cysteine

HCID 6326972
노트반응
기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
18312-66-8
표준 SMILES
NC(C[Se])C(=O)O
InChIKey
FDKWRPBBCBCIGA-UHFFFAOYSA-N
분자식
C3H6NO2Se
평균 분자량
167.06 g/mol
단동위원소 질량
167.95638

개요

Selenocysteine is an alpha-amino acid that consists of alanine where one of the methyl hydrogens is substituted with a seleno group. It has a role as a human metabolite. It contains a selanylmethyl group. It is a conjugate base of a selenocysteinium. It is a conjugate acid of a selenocysteinate(1-).

이름 및 식별자

우선 이름
Seleno-(DL)-cysteine
현지명
셀레노시스테인
영어명
Selenocysteine
분자식
C3H7NO2Se
분자량
168.05

이름 및 동의어

SELENO-(DL)-CYSTEINEAlanine, 3-seleno-HSDB 3534RefChem:884828DL-Selenocysteine3-selanylalanine(S)-2-Amino-3-hydroselenopropanoic acid3-Selenyl-DL-alanineSelenocysteinSelenozysteinDTXSID90863222CHEBI:177792
이름 더 보기
셀레노시스테인Alanine, 3-selenyl-2-Amino-3-hydroselenopropanoic acid
FDKWRPBBCBCIGA-UHFFFAOYSA-N2-Amino-3-hydroselenopropanoicacidKAA23658AKOS006276195

데이터베이스 식별자

CAS
18312-66-8、3614-08-2
PubChem CID
6326972
ChEBI
CHEBI:9093

물성

구조 계산 물성

극성 표면적
63.3 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
3
회전 가능 결합 수
2
무거운 원자 수
7
형식 전하
0
복잡도
75.3

물리화학적 성질

끓는 점
440.2 · 440.2±45.0 °C(Predicted)
산도 계수 (pKa)
2.16 · 2.16±0.10(Predicted)

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

유해성 정보

Special Reports · 5건

Toxicology Review: Clinical Toxicology 5 (2): 175 (1972)

WHO; Evaluation of The Available Toxicity Data On Selenium (1987). Properties and analysis; sources, levels and transport in the environment; human exposure; metabolism; animal studies; effects on man; evaluation of the health risks; quantitative assessment of exposure.

NTIS; Govt Reports Announcements & Index (GRA&I), Issue 14 (1987). This bibliography contains citations concerning the toxicity, carcinogenicity, environmental pollution, and other hazards and adverse effects of selenium. The detection, characterization, analytical methods, and removal from the environment are discussed. Pollution from coal fired and geothermal power plants are considered. (This updated bibliography contains 349 citations, none of which are new entries to the previous edition.)

Najael; Revue g'en'erale de s'ecurite - RGS 63: 65-72 (1987). Information note on the harmful effects of selenium compounds. Physical and chemical properties of selenium and its principal compounds; uses; pathology and toxicology (irritation of the skin and mucous membranes; these irritations are compensable under French law); radioactive selenium; fire hazards; French regulations; protection.

For more Special Reports (Complete) data for SELENO-(DL)-CYSTEINE (10 total), please visit the HSDB record page.

RCRA Requirements · 1건

D010; A solid waste containing selenium (such as seleno-(dl)-cysteine) may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste.

OSHA StandardsPermissible Exposure Limit: Table Z-1 8-Hr Time Weighted Avg: 0.2 mg/cu m. /Selenium cmpd (as Se)/
Atmospheric Standards · 1건

Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Seleno-(DL)-cysteine is included on this list.

화학 및 산업

약리 정보

Absorption, Distribution and ExcretionSelenium, either as inorganic or organic forms, is rapidly absorbed from the human gut, with total bioavailability of 84% to 97%, respectively. /Selenium/

용도 및 제조

General Manufacturing Information · 1건

METHYLMERCURY-D,L-SELENOCYSTEINATE MONOHYDRATE COMPLEX, A KEY MODEL FOR THE METHYLMERCURY(II)-SELENOPROTEIN INTERACTION IN VIVO, WAS PREPARED VIA THE REACTION OF SELENO-D,L-CYSTEINE (FROM PRIOR REDUCTION OF SELENO-D,L-CYSTINE) WITH METHYLMERCURY HYDROXIDE & CHARACTERIZED BY SINGLE-CRYSTAL X-RAY DIFFRACTOMETRY.

공급사3 곳

安那莱(齐河)新材料科技有限公司18600642180(微信同) 13391601435 · [email protected]
常州非凡医药科技有限公司0519-82111935 15195055733 · [email protected]
Nextpeptide Inc+86-0571-81612335 +8613336028439 · [email protected]

추가 설명

정의ChEBI: An alpha-amino acid that consists of alanine where one of the methyl hydrogens is substituted with a seleno group.

관련 반응

0건
반응 기록 만들기

현재 필터 조건에 해당하는 반응 기록이 없습니다.

화합물 노트

불러오는 중…

이 페이지에서기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
EPA Hazardous Waste Number · 1건

D010; A waste containing selenium (such as seleno-(dl)-cysteine) may (or may not) be characterized a hazardous waste following testing for the toxicity characteristics as prescribed by the Resource Conservation and Recovery Act (RCRA) regulations.

NIOSH RecommendationsRecommended Exposure Limit: 10 Hr Time-Weighted Avg: 0.2 mg/cu m. /Selenium/
State Drinking Water Standards · 2건

(AZ) ARIZONA 10 ug/l /Selenium/

(NY) NEW YORK 10 ug/l /Selenium/

State Drinking Water Guidelines · 4건

(AZ) ARIZONA 45 ug/l /Selenium/

(CT) CONNECTICUT 10 ug/l /Selenium/

(ME) MAINE 10 ug/l /Selenium/

(MN) MINNESOTA 30 ug/l /Selenium/

Federal Drinking Water StandardsEPA 50 ug/l /Selenium/
Hazardous Reactivities and IncompatibilitiesAcids, strong oxidizers, chromium trioxide, potassium bromate, cadmium. /Selenium/

안전 및 보호

Disposal MethodsGenerators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number D010, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.
Preventive Measures · 2건

The worker should immediately wash the skin when it becomes contaminated. /Selenium/

Work clothing that becomes wet or significantly contaminated should be removed and replaced. /Selenium/

Threshold Limit Values (TLV) · 2건

8 hr Time Weighted Avg (TWA): 0.2 mg/cu m. /Selenium & compounds, as Se/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Selenium & compounds, as Se/

Personal Protective Equipment (PPE) · 5건

Wear appropriate personal protective clothing to prevent skin contact. /Selenium/

Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. (Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.) /Selenium/

Recommendations for respirator selection. Max. concn for use: 1 mg/cu m. Respirator Class(es): Any dust and mist respirator. If not present as a fume. May require eye protection. Any dust, mist, and fume respirator. May require eye protection. Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter. Any powered, air-purifying respirator with a dust and mist filter. If not present as a fume. May require eye protection. Any powered, air-purifying respirator with a dust, mist, and fume filter. May require eye protection. Any supplied-air respirator. May require eye protection. Any self-contained breathing apparatus with a full facepiece. /Selenium/

Recommendations for respirator selection. Condition: Emergency or planned entry into unknown concentrations or IDLH conditions: Respirator Class(es): Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive pressure-mode. Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive-pressure mode. /Selenium/

Recommendations for respirator selection. Condition: Escape from suddenly occurring respiratory hazards: Respirator Class(es): Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter. Any appropriate escape-type, self-contained breathing apparatus. /Selenium/

Immediately Dangerous to Life or Health (IDLH)1 mg/cu m (as Se) /Selenium/

독성 정보

Interactions · 2건

The effects of cadmium, mercury (Hg), and three different chemicals forms of selenium (selenite, selenocystine, and selenomethionine) on ram spermatozoal motility and oxygen consumption in vitro were studied over a 4 mo period. Concentrations of 10(-6) to 10(-2) M cadmium and mercury were injurious to spermatozoa as indicated by depressed motility and reduced oxygen uptake. Equimolar concentrations of selenium as selenite, selenocystine, or selenomethionine counteracted the toxicity of cadmium and mercury at low concentrations (10(-5) and 10(-6) M) but not at higher concentrations (10(-4) to 10(-2) M). /Selenocystine/

The chemopreventive efficacies of selenate, selenite, selenium dioxide, selenomethionine and selenocystine were examined during the promotion phase of carcinogenesis in the 7,12-dimethylbenz(a)anthracene-induced mammary tumor model in rats. Each agent was added to the diet of a final concentration of 3 ppm selenium. In general, there was no significant difference in the potency of these five selenium compounds in inhibiting the development of mammary tumors. The interaction of vitamin E (500 ppm) with either selenite or selenomethionine was further characterized in a second carcinogenesis study. Results of this experiment suggested that vitamin E enhanced the protective effect of selenite but not that of selenomethionine. In an attempt to explore the synergistic mechanism of selenium and vitamin E, the effects of these two agents on mitogen induced blastogenesis and natural killer cytotoxic activity were also investigated. No consistent changes in these in vitro immune functions were detected resulting from supranutritional feeding of either selenite or vitamin E or both. ... /Cystine/

규제 정보

RCRA Requirements · 1건

D010; A solid waste containing selenium (such as seleno-(dl)-cysteine) may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste.

Atmospheric Standards · 1건

Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Seleno-(DL)-cysteine is included on this list.

State Drinking Water Standards · 2건

(AZ) ARIZONA 10 ug/l /Selenium/

(NY) NEW YORK 10 ug/l /Selenium/

State Drinking Water Guidelines · 4건

(AZ) ARIZONA 45 ug/l /Selenium/

(CT) CONNECTICUT 10 ug/l /Selenium/

(ME) MAINE 10 ug/l /Selenium/

(MN) MINNESOTA 30 ug/l /Selenium/

Federal Drinking Water StandardsEPA 50 ug/l /Selenium/