사이클로프로판
사이클로프로페인 · 사이클로프로판 · TRIMETHYLENE · Cyclopropnane · CYCLOPROPANE · Cyclopropane gas · CYCLOPROPANE, 99+% · trimethylene(cyclic)
식별자 및 물리적 특성
| CAS No. | 75-19-4 |
|---|---|
| 분자식 | C3H6 |
| 평균 분자량 | 42.08 g/mol |
| 단동위원소 질량 | 42.04695019 g/mol |
| SMILES | C1CC1 |
| InChIKey | LVZWSLJZHVFIQJ-UHFFFAOYSA-N |
| PubChem CID | 6351 |
| ChEMBL | CHEMBL1796999 |
| ChEBI | CHEBI:30365 |
| EC No. | 200-847-8 |
| DTXSID | DTXSID4058786 |
| 현지명 | 사이클로프로판 |
화학 및 물리적 성질
| XLogP | 1.6 |
|---|---|
| 극성 표면적 | 0 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 0 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 3 |
| 형식 전하 | 0 |
| 복잡도 | 4 |
| LogP(분배 계수) | log Kow = 1.72 |
| 냄새 | RESEMBLES THAT OF PETROLEUM ETHERMild, sweetOdorlessCharacteristic odor resembling that of solvent naphtha |
| 맛 | PUNGENT |
| 밀도 | 0.676 at -27.4 °F (USCG, 1999) - Less dense than waterwill float1.879 G/L AT 0 °C & 1 ATM1.879 @ 0°C0.6190 |
| Color/Form | COLORLESS GAS |
| 용해도 | OSTWALD SOLUBILITY COEFFICIENT (37 °C) IN H2O: 0.20IN BLOOD: 0.42 AND IN OIL: 11.9FREELY SOL IN ALCOHOL, ETHERSOL IN FIXED OILS, CONCN SULFURIC ACID1 VOL DISSOLVES IN ABOUT 2.7 VOL OF WATER AT 15 °CSoluble in benzenevery soluble in ethanol, ether.3.81X10+2 mg/l water at 35 °C |
| 끓는 점 | -27.2 °F at 760 mmHg (USCG, 1999)-32.8 °C @ 760 MM HG-33.5 °C @760 [mm Hg]−33 °C(lit.) |
| Decomposition | When heated to decomposition it emits acrid smoke and fumes. |
| 녹는점 | -197.3 °F (USCG, 1999)-127.4 °C-126.6 °C−128 °C(lit.) |
| 증기 밀도 | 1.88 (Air= 1)1.45 (vs air) |
| 증기압 | 5.41X10+3 mm Hg at 25 °C/ calculated from experimentally derived coefficients/5410 [mm Hg] @25 °C |
| Surface Tension | 22 dynes/cm= 0.022 N/m @ -40 °C |
| 굴절률 | 1.3799 |
| pKa(산도 계수) | 46(at 25℃) |
| 폭발한계 | 10.4% |
| 용해도 | 464mg/L(25℃) |
| 비열 | Cp(gas): 1.32 J/(g·K), at 25℃ |
| Merck | 13,2777 |
| 헨리 상수 | 1.2×10-4 mol/(m3Pa) at 25℃, Plyasunov and Shock (2000) |
| InChI | InChI=1S/C3H6/c1-2-3-1/h1-3H2 |
| InChIKey | LVZWSLJZHVFIQJ-UHFFFAOYSA-N |
| SMILES | C1CC1 |
| EPA | Cyclopropane (75-19-4) |
화학적 성질
Cyclopropane is a colourless gas, C3H6, b.p. –34.5°C, whose moleculescontain a triangular ring of carbonatoms. It is made by treating 1,3-dibromopropanewith zinc metal, andis used as a general anaesthetic.
안전 및 규제
| GHS 분류 | DangerH220: Extremely flammable gas [Danger Flammable gases]P203, P210, P222, P280, P377, P381, and P403 (click each P-code to see the statement) |
|---|---|
| 규제 정보 | Chemical: CyclopropaneCyclopropane: HSNO Approval: HSR000992 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 운송 라벨(DOT) | Flammable Gas |
| 화재 위험 | Excerpt from ERG Guide 115 [Gases - Flammable (Including Refrigerated Liquids)]:EXTREMELY FLAMMABLE. Will be easily ignited by heat, sparks or flames. Will form explosive mixtures with air. Vapors from liquefied gas are initially heavier than air and spread along ground. CAUTION: Hydrogen (UN1049), Deuterium (UN1957), Hydrogen, refrigerated liquid (UN1966), Methane (UN1971) and Hydrogen and Methane mixture, compressed (UN2034) are lighter than air and will rise. Hydrogen and Deuterium fires are difficult to detect since they burn with an invisible flame. Use an alternate method of detection (thermal camera, broom handle, etc.) Vapors may travel to source of ignition and flash back. Cylinders exposed to fire may vent and release flammable gas through pressure relief devices. Containers may explode when heated. Ruptured cylinders may rocket. CAUTION: When LNG - Liquefied natural gas (UN1972) is released on or near water, product may vaporize explosively. (ERG, 2024)· EXTREMELY FLAMMABLE.· Will be easily ignited by heat, sparks or flames.· Will form explosive mixtures with air.· Vapors from liquefied gas are initially heavier than air and spread along ground.CAUTION: Hydrogen (UN1049), Deuterium (UN1957), Hydrogen, refrigerated liquid (UN1966), Methane (UN1971) and Hydrogen and Methane mixture, compressed (UN2034) are lighter than air and will rise. Hydrogen and Deuterium fires are difficult to detect since they burn with an invisible flame. Use an alternate method of detection (thermal camera, broom handle, etc.)· Vapors may travel to source of ignition and flash back.· Cylinders exposed to fire may vent and release flammable gas through pressure relief devices.· Containers may explode when heated.· Ruptured cylinders may rocket.CAUTION: When LNG - Liquefied natural gas (UN1972) is released on or near water, product may vaporize explosively. |
용도
개요
Cyclopropane (molecular formula: C3H6) is a kind of cycloalkane molecule. Cyclopropane and propene are isomers of each other. It can be used as a kind of anaesthetic. However, due to its side effect of causing a sudden decrease in blood pressure and potentially causing cardiac dysrhythmia, it has not been available for clinical use since mid-1980 as more. Its mechanism of action is through acting as the NMDA receptor antagonist as well as inhibiting the AMPA receptor, inhibiting the nicotine acetylcholine receptor, and activates certain K2P channels.
용도
Cyclopropane was initially investigated because it was thought to be the toxic element in ethylene. Instead, it turned out to be an excellent anesthetic with very rapid onset and recovery while maintaining stable hemodynamics. Its use was ultimately limited because it was highly explosive. Cyclopropane is a sweet-smelling, flammable gas that has little or no laboratory, commercial, or industrial use.
일반 설명
Cyclopropane is a colorless gas with a petroleum-like odor. It is shipped as a liquid at 4-6 atms. It is easily ignited. The vapors are heavier than air. Contact with the liquid may cause frostbite. It can asphyxiate by the displacement of air and has a narcotic effect in high concentration (formerly used as an anesthetic gas). Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket.
제조 및 합성 방법
생산 방법
Cyclopropane is prepared in reagent grade by the reduction of 1,2-dibromocyclopropane with zinc and alcohol.