산화프로필렌
1,2-에폭시프로판 · 산화프로필렌 · 프로필렌옥사이드 · 프로필렌산화물 · 메틸옥시란 · 프로펜산화물 · 메틸에틸렌산 · 1,2-프로필렌 옥사이드
식별자 및 물리적 특성
| CAS No. | 75-56-9 |
|---|---|
| 분자식 | C3H6O |
| 평균 분자량 | 58.08 g/mol |
| 단동위원소 질량 | 58.04186481 g/mol |
| SMILES | CC1CO1 |
| InChIKey | GOOHAUXETOMSMM-UHFFFAOYSA-N |
| PubChem CID | 6378 |
| ChEMBL | CHEMBL2251584 |
| ChEBI | CHEBI:38685 |
| EC No. | 200-879-2 |
| DTXSID | DTXSID5021207 |
| 현지명 | 산화프로필렌 |
화학 및 물리적 성질
| XLogP | 0 |
|---|---|
| 극성 표면적 | 12.5 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 4 |
| 형식 전하 | 0 |
| 복잡도 | 26.5 |
| 물질 분류 | Hazardous Air Pollutants (HAPs)Carcinogens |
| 화장품 | Cosmetics ingredient -> Fragrance |
| 농약 | Pesticide -> EPA IRISPesticides -> Fumigants |
| LogP(분배 계수) | log Kow= 0.03. |
| 냄새 | ODOR IS SWEET, ALCOHOLIC, & LIKE ETHER OR BENZENEIn foods, propylene oxide has no residual odor.Ethereal odor... Benzene-like odor ...미묘한특성달콤한, 알코올 중독천연가스처럼. |
| 맛 | In foods, propylene oxide has no residual taste. |
| 식품 첨가물 | Use unspecified -> FDA Substance added to food |
| 밀도 | 0.859 at 32 °F (EPA, 1998) - Less dense than waterwill float0.8304 @ 20/20 °CRelative density (water = 1): 0.830.8304 @ 20°C0.83 g/mL at 25 °C(lit.) |
| Viscosity | 0.28 centipoise at 25 °C0.34 mm²/s at 25 °C |
| Color/Form | Colorless liquid ... [Note: A gas above 94 degrees F.] |
| 용해도 | greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)Solubility of water in propylene oxide is 12.8% by wt at 20 °C.40.5 wt% water @ 20 °CMISCIBLE WITH ACETONE, BENZENE, CARBON TETRACHLORIDE, METHANOL, & ETHERSoluble in alcohol and ether.In water, 590,000 mg/l @ 25 °C425-450g/l |
| Corrosivity | NONCORROSIVE TO METALS |
| 녹는점 | -112 °C |
| 끓는 점 | 34 °C(lit.) |
| 증기 밀도 | 2 (vs air) |
| 증기압 | 29.43 psi ( 55 °C) |
| 굴절률 | n20/D 1.366(lit.) |
| 인화점 | −35 °F |
| 저장 조건 | 2-8°C |
| 물리적 상태 | 액체 |
| 색상 | 투명한 |
| 폭발한계 | 1.9-36%(V) |
| 용해도 | 40g/100mL(20℃) |
| 비열 | Cp(liquid): 2.07 J/(g·K)Cp(gas): 1.25 J/(g·K), at 25℃ |
| Merck | 14,7856 |
| BRN | 79763 |
| 헨리 상수 | Not an environmentally important parameter because propylene oxide reacts rapidly with water |
| 안정성 | Stable. Incompatible with acids, bases, oxidizing agents, copper, copper alloys, brass, bronze, iron, metal chlorides, peroxides and a wide variety of other materials. Reacts with compounds containing labile hydrogen. Extremely flammable - note low boiling point, low flash point and very wide explosion limits. Moisture sensitive. |
| InChI | 1S/C3H6O/c1-3-2-4-3/h3H,2H2,1H3 |
| InChIKey | GOOHAUXETOMSMM-UHFFFAOYSA-N |
| SMILES | CC1CO1 |
| LogP(분배 계수) | 0.030 |
| NIST | Propylene oxide(75-56-9) |
| EPA | Propylene oxide (75-56-9) |
화학적 성질
Propylene oxide is soluble in water and miscible with most organic solvents. It is found to be an excellent low-boiling solvent for cellulose acetate, nitrocellulose, adhesive compositions and vinyl chloride-acetate resins. It is also a solvent for hydrocarbons, gums and shellac. Some of its uses are as a solvent and stabilizer in DDT aerosol-type insecticides, and as a fumigant and food preservative. Since it is an acid acceptor, it is also used as a stabilizer for vinyl chloride resins and other chlorinated systems.
안전 및 규제
| GHS 분류 | DangerH224: Extremely flammable liquid and vapor [Danger Flammable liquids]P203, P210, P233, P240, P241, P242, P243, P261, P262, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P318, P319, P321, P330, P337+P317, P361+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)This chemical does not meet GHS hazard criteria for < 0.1% (1 of 3209) of reports.H224 (99.2%): Extremely flammable liquid and vapor [Danger Flammable liquids] |
|---|---|
| 규제 정보 | Chemical: Oxirane, methyl-Hazard Traits - CarcinogenicityDermatotoxicityDevelopmental ToxicityGenotoxicityNeurotoxicityOcular ToxicityReproductive ToxicityRespiratory ToxicityOxirane, 2-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Oxirane, 2-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Propylene oxide is listed in the dataset of EPA Human Health Benchmarks for Pesticides under the Safe Drinking Water Act (40 eCFR 141)Status: Active Update: 26-10-2012 https://echa.europa.eu/registration-dossier/-/registered-dossier/1263Substance: Methyloxirane (Propylene oxide) |
| 기타 안전 정보 | IMAP assessments - Methyloxirane (R-, S- and (R,S)-): Human health tier II assessment |
| 운송 라벨(DOT) | Flammable Liquid |
| 화재 위험 | Vapor is heavier than air and may travel considerable distance to source of ignition and flash back. Vapors form explosive mixture with air. If polymerization takes place in container, there may be a violent rupture of container. Explosion hazard is severe when exposed to flame. Violently reacts with acetylide- forming metals such as copper or copper alloys, ammonium hydroxidechlorosulfonic acidhydrochloric acidhydrofluoric acidnitric acidoleum and sulfuric acid. Hazardous polymerization may occur. Avoid active catalytic surfaces such as anhydrous chlorides of iron, tin, and aluminum |
용도
개요
Propylene oxide is an allergic and irritant agent, used as a solvent and raw material in the chemical industry as starting material and intermediate for a broad spectrum of polymers.
용도
Propylene oxide is used as a fumigant forfoodstuffs; as a stabilizer for fuels, heat-ing oils, and chlorinated hydrocarbons; asa fuel–air explosive in munitions; and toenhance the decay resistance of wood andparticleboard (Mallari et al. 1989). Recentstudies indicate that the fumigant potentialof propylene oxide enhances at a low pres-sure of 100 mm Hg which could render it asan alternative to methyl bromide for rapiddisinfection of commodities (Isikber et al.2004).
일반 설명
A clear colorless volatile liquid with an ethereal odor. Flash point -35°F. Boiling point 95°F. Density 6.9 lb./gal. Flammable over a wide range of vapor-air concentrations. If contaminated, may polymerize with evolution of heat and possible rupture of container. Vapors irritate eyes, skin, and respiratory system. Prolonged contact with skin may result in delayed burns. Vapors heavier than air. Used as a fumigant, in making detergents and lubricants, and to make other chemicals.
제조 및 합성 방법
생산 방법
Propylene oxide is synthesized commercially from propylene through the intermediate propylene chlorohydrin. It also can be made by peroxidation of propylene using alkylhydroperoxides, but this method produces coproducts as well, often styrene or cumene. Propylene oxide is also synthesized via oxidation of propylene with hydrogen peroxide, which produceswater as the only coproduct.