Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용

HCID 638024생성일: 2026년 11월 2일

Piperine

5-stilbenediol · (E/Z)-Piperine · SichuanPepper oil · 1-piperoylpiperidine (Standard) · 1-piperoylpiperidine, 10 mM in DMSO · 1-Piperidino-5-(1,3-benzodioxole-5-yl)-2,4-pentadiene-1-one · 1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine · 2,4-Pentadien-1-one, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-

https://huagongshe.com/ko/chemical/638024

식별자 및 물리적 특성

CAS No.	7780-20-3
분자식	C17H19NO3
평균 분자량	285.34 g/mol
단동위원소 질량	285.13649347 g/mol
SMILES	O=C(/C=C/C=C/c1ccc2c(c1)OCO2)N1CCCCC1
InChIKey	MXXWOMGUGJBKIW-YPCIICBESA-N
PubChem CID	638024
ChEMBL	CHEMBL43185
ChEBI	CHEBI:28821
EC No.	202-348-0
DTXSID	DTXSID3021805

화학 및 물리적 성질

XLogP	3.5
극성 표면적	38.8
수소 결합 공여자 수	0
수소 결합 수용자 수	3
회전 가능 결합 수	3
무거운 원자 수	21
형식 전하	0
복잡도	412
물질 분류	Other Uses -> Food Additives
의약품	Pharmaceuticals -> Listed in ZINC15
SpringerMaterials Properties	Viscosity
향료	Fragrance Ingredient (Piperine) -> IFRA transparency List
식품 첨가물	FLAVORING AGENT OR ADJUVANT -> FDA Substance added to food
향미제	EU Flavoring substances
용해도	0.04 mg/mL at 18 °CVery slightly soluble in waterSoluble in ether, oilsSoluble (in ethanol)
Human Drugs	Breast FeedingLactationMilk, HumanCytochrome P-450 Enzyme Inhibitors
끓는 점	498.00 to 499.00 °C. @ 760.00 mm Hg498.5±40.0 °C(Predicted)
녹는점	129 °C
증기압	0.00000013 [mmHg]
Physical Description	Light yellow to yellow solid with a pungent odor[Reference #1] Light yellow solid[Sigma-Aldrich MSDS]Virtually colourless white crystalsAroma reminiscent of pepper
밀도	1.211±0.06 g/cm3(Predicted)
저장 조건	Store at room temperature
pKa(산도 계수)	-0.71±0.20(Predicted)
InChI	InChI=1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2
InChIKey	MXXWOMGUGJBKIW-UHFFFAOYSA-N
SMILES	C(N1CCCCC1)(=O)C=CC=CC1=CC=C2OCOC2=C1
LogP(분배 계수)	3.365 (est)

안전 및 규제

GHS 분류	DangerH301 (93.4%): Toxic if swallowed [Danger Acute toxicity, oral]P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 1804 reports by companies from 7 notifications to the ECHA C&L Inventory.
규제 정보	Chemical: Piperidine, 1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-, (E,E)-Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)Piperine: Does not have an individual approval but may be used under an appropriate group standard
유해성 요약	A mild skin and eye irritant[Reference #1] Safe when used as a flavoring agent in food[JECFA] May cause irritationHarmful by ingestion[Sigma-Aldrich MSDS]
Hazard Classes and Categories	Acute Tox. 3 (93.4%)
Effects During Pregnancy and Lactation	◉ Summary of Use during Lactation

Piperine

CAS No.

7780-20-3

분자식

C17H19NO3

평균 분자량

285.34 g/mol

단동위원소 질량

285.13649347 g/mol

SMILES

O=C(/C=C/C=C/c1ccc2c(c1)OCO2)N1CCCCC1

InChIKey

MXXWOMGUGJBKIW-YPCIICBESA-N

PubChem CID

638024

ChEMBL

CHEMBL43185

ChEBI

CHEBI:28821

EC No.

202-348-0

DTXSID

DTXSID3021805

화학 및 물리적 성질

XLogP

3.5

극성 표면적

38.8

수소 결합 공여자 수

수소 결합 수용자 수

회전 가능 결합 수

무거운 원자 수

형식 전하

복잡도

412

물질 분류

Other Uses -> Food Additives

의약품

Pharmaceuticals -> Listed in ZINC15

SpringerMaterials Properties

Viscosity

향료

Fragrance Ingredient (Piperine) -> IFRA transparency List

식품 첨가물

FLAVORING AGENT OR ADJUVANT -> FDA Substance added to food

향미제

EU Flavoring substances

용해도

0.04 mg/mL at 18 °CVery slightly soluble in waterSoluble in ether, oilsSoluble (in ethanol)

Human Drugs

Breast FeedingLactationMilk, HumanCytochrome P-450 Enzyme Inhibitors

끓는 점

498.00 to 499.00 °C. @ 760.00 mm Hg498.5±40.0 °C(Predicted)

녹는점

129 °C

증기압

0.00000013 [mmHg]

Physical Description

Light yellow to yellow solid with a pungent odor[Reference #1] Light yellow solid[Sigma-Aldrich MSDS]Virtually colourless white crystalsAroma reminiscent of pepper

밀도

1.211±0.06 g/cm3(Predicted)

저장 조건

Store at room temperature

pKa(산도 계수)

-0.71±0.20(Predicted)

InChI

InChI=1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2

InChIKey

MXXWOMGUGJBKIW-UHFFFAOYSA-N

SMILES

C(N1CCCCC1)(=O)C=CC=CC1=CC=C2OCOC2=C1

LogP(분배 계수)

3.365 (est)

안전 및 규제

GHS 분류

DangerH301 (93.4%): Toxic if swallowed [Danger Acute toxicity, oral]P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 1804 reports by companies from 7 notifications to the ECHA C&L Inventory.

규제 정보

Chemical: Piperidine, 1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-, (E,E)-Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)Piperine: Does not have an individual approval but may be used under an appropriate group standard

유해성 요약

A mild skin and eye irritant[Reference #1] Safe when used as a flavoring agent in food[JECFA] May cause irritationHarmful by ingestion[Sigma-Aldrich MSDS]

Hazard Classes and Categories

Acute Tox. 3 (93.4%)

Effects During Pregnancy and Lactation

◉ Summary of Use during Lactation