Liquid density at 28 °C: 1.291 g/mLRelative density (water = 1): 1.31.5678 @ -42°C5.55(relative gas density)1,568 g/cm3
Viscosity
0.193 cP at 25 °C (liquid)0.0125 cP at 25 °C, 101.3 kPa (vapor)
Color/Form
Colorless gasColorless gas ... [Note: Shipped as a liquefied compressed gas]
용해도
0.006 % at 77 °F (NIOSH, 2024)In water, 58 mg/L at 25 °CSoluble in ethanol, ether0.058 mg/mL at 25 °CSolubility in water: none(77 °F): 0.006%
Corrosivity
... Does not attack metals except at elevated temperatures.
끓는 점
-38 °F at 760 mmHg (NIOSH, 2024)-39.1 °C-39 °C-37.7 °C @760 [mm Hg]-39°C
녹는점
30-31°C
굴절률
1.2210
인화점
70°C
물리적 상태
무색 가스
용해도
불용성
비열
Cp(gas): 1.19 J/(g·K), at 25℃
헨리 상수
3.4×10-6 mol/(m3Pa) at 25℃, Wilhelm et al. (1977)
LogP(분배 계수)
2.468 (est)
NIST
Ethane, chloropentafluoro-(76-15-3)
EPA
CFC-115 (76-15-3)
화학적 성질
Chloropentafluoroethane is a colorless, odorless, nonflammable gas. Ethereal odor. Shipped as a liquefied compressed gas.
안전 및 규제
GHS 분류
WarningH280 (100%): Contains gas under pressuremay explode if heated [Warning Gases under pressure]P410+P403, and P502 (click each P-code to see the statement)Aggregated GHS information provided per 112 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Not Classified
규제 정보
Chemical: Ethane, chloropentafluoro-Chloropentafluoroethane (Refrigerant gas R115): Non hazardousThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
운송 라벨(DOT)
Non-Flammable Gas
화재 위험
Excerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:· Some may burn but none ignite readily.Not combustible. Heating will cause rise in pressure with risk of bursting. Gives off irritating or toxic fumes (or gases) in a fire.
화재 가능성
Nonflammable
건강 유해성
Excerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:· Vapors may cause dizziness or asphyxiation without warning, especially when in closed or confined areas.
유해성 요약
See CHLOROFLUOROCARBONSPossible frostbite from contact with liquid[ICSC]
운송 번호 및 가이드(DOT)
1020 126
FDA 요건
The Food and Drug Administration (FDA), after consultation with the Environmental Protection Agency (EPA), is amending FDA's regulation on the use of ozone-depleting substances (ODSs) in selfpressurized containers to remove the essential-use designations for flunisolide, triamcinolone, metaproterenol, pirbuterol, albuterol and ipratropium in combination, cromolyn, and nedocromil used in oral pressurized metered-dose inhalers (MDIs). The Clean Air Act requires FDA, in consultation with the EPA, to determine whether an FDA-regulated product that releases an ODS is an essential use of the ODS. FDA has concluded that there are no substantial technical barriers to formulating flunisolide, triamcinolone, metaproterenol, pirbuterol, albuterol and ipratropium in combination, cromolyn, and nedocromil as products that do not release ODSs, and therefore they will no longer be essential uses of ODSs as of the effective dates of this rule. MDIs for these active moieties containing an ODS may not be marketed after the relevant effective date. DATES: Removal of Part 2.125(e)(2)(iii) and 2.125(e)(4)(vii) is effective June 14, 2010. Removal of Part 2.125(e)(1)(v) and 2.125(e)(4)(iv) is effective December 31, 2010. Removal of Part 2.125(e)(1)(iii) is effective June 30, 2011. Removal of 2.125(e)(2)(iv) and Part 2.125(e)(4)(viii) is effective December 31, 2013. /Ozone-Depleting Substances/
용도
용도
Chloropentafluoroethane is a propellant and aerating agent for foamed or sprayed foods.
일반 설명
Chloropentafluoroethane is a colorless odorless gas with an ether-like odor. Chloropentafluoroethane is shipped as a liquefied gas under its own vapor pressure. Chloropentafluoroethane is noncombustible. Chloropentafluoroethane can asphyxiate by the displacement of air. Contact with the liquid can cause frostbite. Exposure of the container to prolonged heat or fire may cause Chloropentafluoroethane to rupture violently and rocket.
Use of ozone-depleting substances in foods, drugs, devices, or cosmetics. (a) As used in this section, ozone-depleting substance (ODS) means any class I substance as defined in 40 CFR part 82, appendix A to subpart A, or class II substance as defined in 40 CFR part 82, appendix B to subpart A. (b) Except as provided in paragraph (c) of this section, any food, drug, device, or cosmetic that is, consists in part of, or is contained in an aerosol product or other pressurized dispenser that releases an ODS is not an essential use of the ODS under the Clean Air Act. (c) A food, drug, device, or cosmetic that is, consists in part of, or is contained in an aerosol product or other pressurized dispenser that releases an ODS is an essential use of the ODS under the Clean Air Act if paragraph (e) of this section specifies the use of that product as essential. For drugs, including biologics and animal drugs, and for devices, an investigational application or an approved marketing application must be in effect, as applicable. ... (e) The use of ODSs in the following products is essential: ... (2) Metered-dose short-acting adrenergic bronchodilator human drugs for oral inhalation. Oral pressurized metered-dose inhalers containing the following active moieties: ... (iv) Pirbuterol. ... (4) Other essential uses. (iii) Anesthetic drugs for topical use on accessible mucous membranes of humans where a cannula is used for application. ... (vi) Metered-dose atropine sulfate aerosol human drugs administered by oral inhalation. ... (viii) Metered-dose ipratropium bromide and albuterol sulfate, in combination, administered by oral inhalation for human use. (ix) Sterile aerosol talc administered intrapleurally by thoracoscopy for human use. /Ozone-Depleting Substances/
The food additive chloropentafluoroethane may be safely used in food in accordance with the following prescribed conditions: (a) The food additive has a purity of not less than 99.97 percent, and contains not more than 200 parts per million saturated fluoro compounds and 10 parts per million unsaturated fluoro compounds as impurities. (b) The additive is used or intended for use alone or with one or more of the following substances: Carbon dioxide, nitrous oxide, propane, and octafluorocyclobutane complying with part 173.360, as an aerating agent for foamed or sprayed food products, with any propellant effect being incidental and no more than is minimally necessary to achieve the aerating function, except that use is not permitted for those standardized foods that do not provide for such use. (c) To assure safe use of the additive (1) The label of the food additive container shall bear, in addition to the other information required by the act, the following: (i) The name of the additive, chloropentafluoroethane. (ii) The percentage of the additive present in the case of a mixture. (iii) The designation "food grade". (2) The label or labeling of the food additive container shall bear adequate directions for use.
반응성 그룹
Fluorinated Organic Compounds
UN 분류
UN Hazard Class: 2.2
Special Reports
Zakhari S, Aviado DMCardiovascular Toxicology of Aerosol Propellants, Refrigerants and Related SolventsTarget Organ Toxicology Series: Cardiovascular Toxicology, XII+ 388 pagesRaven Press: New York, NY 281-326 (1982). Review of the toxicology of aerosol propellants, refrigerants and related solvents on the cardiovascular system of humans.Production and Consumption of Ozone Depleting Substances under the Montreal Protocol 1986 - 2004[UNEPOzone Secretariat UNEP November 2005, Available from, as of march 11, 2013: http://ozone.unep.org/Publications/Production_and_consumption2005.pdf]The Montreal Protocol on Substances that Deplete the Ozone Layer[UNEPOzone Secretariat United Nations Environment Programme, The Montreal Protocol on Substances that Deplete the Ozone Layer, Available from, as of March 11, 2013: http://ozone.unep.org/pdfs/Montreal-Protocol2000.pdf]Achievements in Stratospheric Ozone Protection Progress Report: This report covers the important and substantial achievements of the people, programs, and organizations that are working to protect the Earth's ozone layer. As impressive as these accomplishments are, our work is not done. Even though we have reduced or eliminated the use of many ozone-depleting substances, some still remain. Additionally, since ozone-depleting substances persist in the air for long periods of time, the past use of these substances continues to affect the ozone layer today. We must also continue to ensure that the alternatives being brought to the market support the country's long-term environmental goals in a cost-effective manner.[EPAAchievements in Stratospheric Ozone Protection Progress Report, Available from, as of March 11, 2013: http://www.epa.gov/ozone/downloads/spd-annual-report_final.pdf]For more Special Reports (Complete) data for CHLOROPENTAFLUOROETHANE (6 total), please visit the HSDB record page.
Reactivity Profile
CHLOROPENTAFLUOROETHANE is incompatible with the following: Alkalis, alkaline earth metals (e.g., aluminum powder, sodium, potassium, zinc) (NIOSH, 2024).
소화
Excerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep cylinder cool by spraying with water.
응급 조치
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Refer for medical attention .First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
누출 비상 조치
· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· Do not touch or walk through spilled material.
응급 처치
Excerpt from NIOSH Pocket Guide for Chloropentafluoroethane:General First Aid:(General first aid procedures)
If material on fire or involved in fire: Extingiush fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.
보관 조건
Fireproof if in building. Cool.
정리 방법
Ventilation. Never direct water jet on liquid. Personal protection: chemical protection suit including self-contained breathing apparatus.
비화재 누출 대응
Excerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:
처리 방법
SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air qualitypotential migration in soil or watereffects on animal and plant lifeand conformance with environmental and public health regulations.Because of recent discovery of potential ozone decomposition in the stratosphere by fluorotrichloromethane, this material should be released to the environment only as a last resort. Waste material should be /recovered and/ returned to the vendor, or to licensed waste disposal company.
누출 처리
Ventilation. NEVER direct water jet on liquid. Personal protection: chemical protection suit including self-contained breathing apparatus.
상호 작용
... The combination of fluorocarbon with a sympathomimetic bronchodilator is potentially dangerous for the treatment of bronchial asthma. For the same reason, sympathomimetic drugs are contraindicated in cardiac resuscitation of patients suffering from fluorocarbon poisoning. /Fluorocarbon poisoning//In humans/ a 10 to 90% mixture of CFC-11 & CFC-12, respectively, caused more severe respiratory effects than either fluorocarbon inhaled singly.
표적 장기
Skin, central nervous system, cardiovascular system
환경 거동
TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 200(SRC), determined from a structure estimation method(2), indicates that chloropentafluoroethane is expected to have high mobility in soil(SRC). Volatilization of chloropentafluoroethane from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 5.6 atm-cu m/mole(SRC), based upon its vapor pressure, 6860 mm Hg(3), and water solubility, 58 mg/L(4). Chloropentafluoroethane is expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(3). Highly chlorinated/fluorinated compounds such as chloropentafluoroethane are not expected to biodegrade rapidly(5).AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 200(SRC), determined from a structure estimation method(2), indicates that chloropentafluoroethane is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is(3) based upon an estimated Henry's Law constant of 5.6 atm-cu m/mole(SRC), derived from its vapor pressure, 6860 mm Hg(4), and water solubility, 58 mg/L(5). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 4 hours and 5 days, respectively(SRC). According to a classification scheme(6), an estimated BCF of 20(SRC), from an estimated log Kow of 2.47(7) and a regression-derived equation(8), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Highly chlorinated/fluorinated compounds such as chloropentafluoroethane are not expected to biodegrade rapidly(9).ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), chloropentafluoroethane, which has a vapor pressure of 6860 mm Hg at 25 °C(2), is expected to exist solely as a gas in the ambient atmosphere. Gas-phase chloropentafluoroethane is essentially inert in the troposphere(3). Chlorpentafluoroethane will gradually diffuse into the stratosphere above the ozone layer where it will slowly degrade due to direct photolysis from UV-C radiation and contribute to the catalytic removal of stratospheric ozone(3). The atmospheric lifetime of this compound has been estimated at 330 years(4).
유해 작용
Neurotoxin - Acute solvent syndrome
노출 경로
The substance can be absorbed into the body by inhalation.inhalation, skin and/or eye contact (liquid)
Average Daily Intake
AIR INTAKE: Assuming the average tropospheric concentration of chloropentafluoroethane is about 4.1 parts per trillion (25.9 ng/cu m)(1), the average daily intake would be about 518 ng/day(SRC).
Approximately 4,500 tons of chloropentafluoroethane were released annually before its production was discontinued(1). Cloropentafluoroethane emissions of 0.4 Gg/year from the United States have been calculated(2).
ICSC Environmental Data
Avoid release to the environment because of its impact on the ozone layer.
Soil Adsorption/Mobility
Using a structure estimation method based on molecular connectivity indices(1), the Koc of chloropentafluoroethane can be estimated to be 200(SRC). According to a classification scheme(2), this estimated Koc value suggests that chloropentafluoroethane is expected to have moderate mobility in soil.
Atmospheric Concentrations
RURAL/REMOTE: Chloropentafluoroethane was detected in the troposphere at an average global concentration of 4.1 parts per trillion(1). The concentration of chloropentafluoroethane in the atmosphere at altitudes ranging from about 10 to 34 km was found to be approximately 1-5 parts per trillion during 1979 and 1980 monitoring(2,3).
Human Toxicity Excerpts
/HUMAN EXPOSURE STUDIES/ /Propellant /fluorocarbon/ gases were generated ... from a distance of 50 cm for periods of 15 to 60 seconds. At a measured concentration of 95,000 mg/cu m (1700 ppm), there was biphasic change in ventilatory capacity, the first reduction occurring within few min after exposure, & second delayed until 13 to 30 min after exposure. Most subjects developed bradycardia, & inversion of the t-wave. /Propellant gases//SIGNS AND SYMPTOMS/ Early ... human experience indicated that high vapor concn (eg, 20%) may cause confusion, pulmonary irritation, tremors & rarely coma, but that these effects were generally transient & without late sequelae. Cause of death /from abuse of fluorocarbons/ is in considerable doubt. Freezing of airway soft tissues can probably be eliminated as a cause of death except in cases where the product was sprayed directly into the mouth from its container or from a balloon containing some liquid. Laryngeal spasm or edema, oxygen displacement, or sensitization of myocardium to endogenous catecholamines with subsequent ventricular fibrillation appear to be reasonable possibilities. /Fluorocarbon refrigerants & propellants//SIGNS AND SYMPTOMS/ Non-occupational exposure and accidental or abusive inhalation of aerosols /due to Fluorocarbon propellants/ have also been documented, the main symptoms being CNS depression and cardiovascular reactions. Cardiac arrhythmia, possibly aggravated by elevated levels of catecholamines due to stress or by moderate hypercapnia, is suggested as the cause of these adverse response, which may lead to death./SIGNS AND SYMPTOMS/ ... High vapor concn (eg, 20%) may cause confusion, pulmonary irritation, tremors & rarely coma ... but ... these effects were generally transient & without late sequelae. /Fluorocarbon refrigerants & propellants/For more Human Toxicity Excerpts (Complete) data for CHLOROPENTAFLUOROETHANE (12 total), please visit the HSDB record page.
직업 노출 등급(OEB)
A
직업 노출 한계(OEL)
TWA: 1000 ppm (6320 mg/m3)
TSCA 등재 상태
TSCA listed
운송 번호(UN)
UN 1020 (CHLOROPENTAFLUORO- ETHANE (REFRIGERANT GAS R 115))
