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기본 정보
- CAS
107140-30-7- 표준 SMILES
CC(=C/C(C)C/C=C/C(C)=C/C(CO)C(=O)C(C)C(O)C(C)C/C(C)=C/C(=O)O)/C=C/C1OC(=O)C=CC1C- InChIKey
OOQHBJFDAPXZJM-BBHORLQHSA-N- 분자식
- C32H46O7
- 평균 분자량
- 542.7 g/mol
이름 및 식별자
- 우선 이름
- PD 124895
- 영어명
- PD 124895
- 분자식
- C32H46O7
- 분자량
- 542.7
이름 및 동의어
Kazusamycin BCL-1957EPD 124895Antibiotic CL-1957EAntibiotic PD-124895HydroxyleptoMycin A, CL 1957E, PD 124895, PD 124,8954,8,10,14,18,20,22-Heptamethyl-16-hydroxymethyl-5,19-dihydroxy-17-oxo-2,6,8,12,14,22-tetracosahexenedioic acid δ-lactone6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15,17-hexamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15,17-hexamethyl-8-oxo-, (2E,10E,12E,16Z,18E)-
데이터베이스 식별자
- CAS
107140-30-7- PubChem CID
- 6436293
물성
물리화학적 성질
- 끓는 점
- 754.197 · 754.197±60.00 °C(Press: 760.00 Torr)(predicted)
- 밀도
- 1.118 · 1.118±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- DMSO에 용해됨
- 물리적 상태
- 무색 필름.
- 산도 계수 (pKa)
- 5.104 · 5.104±0.33(predicted)
화학 및 산업
응용 분야
용도Kazusamycin B is a minor component of the leptomycin complex produced by some Streptomyces sp.. It is an hydroxylated analogue of leptomycin A, a nuclear export inhibitor. Kazusamycin B displays potent antitumour activity against L1210 and human colon adenocarcinoma, and in vivo activity against P388 lymphocytic leukemia in mice. Kazusamycin B also possesses strong antibacterial and antifungal activity.
공급사15 곳
上海赛可锐生物科技有限公司021-58000709 13120558703 · [email protected]
Aladdin Scientific[email protected]
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上海维亦特生物科技有限公司15317051735 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
浙江珲达生物科技有限公司0571-89903022 18679456698 · [email protected]
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西安莱茵生物科技有限公司86-(0)29-85992781 17792393971 · [email protected]
Novachemistry44-20819178-90 02081917890 · [email protected]
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