Triphenylstannane

TRIPHENYLTIN · TRIPHENYLSTANNANE · triphenyl-stannan · Stannane, triphenyl- · Triphenyltin hydride · Triphenylhydridetin(IV) · triphenylstannylhydride · Triphenyltin hydride,95%

https://huagongshe.com/ko/chemical/6460

식별자 및 물리적 특성

CAS No.	892-20-6
분자식	C18H16Sn
평균 분자량	351 g/mol
단동위원소 질량	352.02739521 g/mol
SMILES	c1cc[c]([SnH]([c]2ccccc2)[c]2ccccc2)cc1
InChIKey	NFHRNKANAAGQOH-UHFFFAOYSA-N
PubChem CID	6460
ChEBI	CHEBI:30537
EC No.	212-967-8
DTXSID	DTXSID40893312

화학 및 물리적 성질

극성 표면적	0
수소 결합 공여자 수	0
수소 결합 수용자 수	0
회전 가능 결합 수	3
무거운 원자 수	19
형식 전하	0
복잡도	202
Endocrine Disruptors	Potential endocrine disrupting compound
녹는점	28 °C (lit.)
끓는 점	163-165 °C/0.3 mmHg (lit.)
밀도	1.374 g/mL at 25 °C (lit.)
굴절률	n20/D 1.632(lit.)
인화점	>230 °F
저장 조건	2-8°C
물리적 상태	고체
비중	1.374
색상	White, colorless
용해도	물에 불용성.
BRN	3544353
InChI	1S/3C6H5.Sn.H/c31-2-4-6-5-3-1/h31-5H
InChIKey	NFHRNKANAAGQOH-UHFFFAOYSA-N
SMILES	c1ccc(cc1)[SnH](c2ccccc2)c3ccccc3
EPA	Triphenyltin (892-20-6)

화학적 성질

opalescent colorless or milky white to pale yellow. Soluble in many common organic solvents; usually used in benzene or toluene.

안전 및 규제

GHS 분류	DangerH301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]P261, P262, P264, P270, P271, P273, P280, P301+P316, P302+P352, P304+P340, P316, P321, P330, P361+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 43 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
규제 정보	Council Regulation (EEC) No 315/1993Triphenyltin hydride: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and Categories	Acute Tox. 3 (100%)
건강 영향	Breathing or swallowing, or skin contact with organotins, can interfere with the way the brain and nervous system work, causing death in severe cases. Organic tin compounds may also damage the immune and reproductive system. (L307, L308)
노출 경로	Oral (L308)inhalation (L308)dermal (L308)
독성 요약	Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local release of pro-inflammatory cytokines, tumor necrosis factor-_, and/or interleukins. They may also induce apoptosis by direct action on neuronal cells. Organotin compounds stimulate the neuronal release of and/or decrease of neuronal cell uptake of neurotransmitters in brain tissue, including aspartate, GABA, glutamate, norepinephrine, and serotonin. This may be either a contributing factor to or result of the neuronal cell loss. The immunotoxic effects of organotins are characterized by thymic atrophy caused by the suppression of proliferation of immature thymocytes and apoptosis of mature thymocytes. Organotin compounds are believed to exert these effects by suppressing DNA and protein synthesis, inducing the expression of genes involved in apoptosis (such as nur77), and disrupting the regulation of intracellular calcium levels, giving rise to the uncontrolled production of reactive oxygen species, release of cytochrome c to the cytosol, and the proteolytic and nucleolytic cascade of apoptosis. The suppression of proliferation of immature thymocytes further results in the suppression of T-cell-mediated immune responses. Organotins are also endocrine disruptors and are believed to contribute to obesity by inappropriate receptor activation, leading to adipocyte differentiation. Inorganic tin triggers eryptosis, contributing to tin-induced anemia. (L308, A182, A184)

용도

Although the triphenyltins exhibit some curative effect, they are used mainly as protectants for control of a range of diseases, examples being early and late blights of potato and leaf spots on sugar beet and peanut.