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플루옥손

Calcein

HCID 65079
노트반응
기본 정보이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
1461-15-0
표준 SMILES
O=C(O)CN(CC(=O)O)Cc1cc2c(cc1O)Oc1cc(O)c(CN(CC(=O)O)CC(=O)O)cc1C21OC(=O)c2ccccc21
InChIKey
DEGAKNSWVGKMLS-UHFFFAOYSA-N
분자식
C30H26N2O13
평균 분자량
622.5 g/mol
단동위원소 질량
622.14348889

이름 및 식별자

우선 이름
Calcein
IUPAC
2-[[7'-[[bis(carboxymethyl)amino]methyl]-3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-2'-yl]methyl-(carboxymethyl)amino]acetic acid
현지명
플루옥손
영어명
Calcein
분자식
C30H26N2O13
분자량
622.53

이름 및 동의어

calceinFluorexon1461-15-0OftasceineOftasceinaOftasceinumV0YM2B16TSNSC-2981932',7'-Bis((bis(carboxymethyl)amino)methyl)fluoresceinNSC298193Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl)bis(methylene)]bis[N-(carboxymethyl)-2,7-Bis(N,N-bis(carboxymethyl)aminomethylene)fluorescein
이름 더 보기
플루옥손3,3'-BIS[N,N-BIS(CARBOXYMETHYL)AMINOMETHYL]FLUORESCEINCALCEINEFLUREXONEN,N'-[[3'FLUOREXONEoftasccineNsc 298193
CHEBI:51903N,N'-(3',6'-Dihydroxyspiro(phthalid-3,9'-xanthen)-2',7'-diyldimethyl)bis(iminodiessigsaeure)Glycine, N,N'-((3',6'-dihydroxy-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-2',7'-diyl)bis(methylene))bis(N-(carboxymethyl)-RefChem:1679752-(((7'-((bis(carboxymethyl)amino)methyl)-3',6'-dihydroxy-3-oxo-3H-spiro(2-benzofuran-1,9'-xanthene)-2'-yl)methyl)(carboxymethyl)amino)acetic acid215-957-1DTXCID6025856DTXSID8045856

데이터베이스 식별자

CAS

물성

구조 계산 물성

XLogP
-3.1
극성 표면적
232 Ų
수소 결합 공여자 수
6
수소 결합 수용자 수
15
회전 가능 결합 수
12
무거운 원자 수
45
형식 전하
0
복잡도
1,070

실험 및 물리화학적 성질

Physical DescriptionOrange powder; [Acros Organics MSDS]

물리화학적 성질

녹는점
200 °C · 200 °C
끓는 점
662.7 °C · 662.7°C (rough estimate)
밀도
1.4388 · 1.4388 (rough estimate)
굴절률
1.58 · 1.5800 (estimate)
저장 조건
Keep in dark place,Sealed in dry,Room Temperature
용해도
2 O: · H2O: 용해성
물리적 상태
가루
산도 계수 (pKa)
6.67 · 6.67(at 25℃)
색상
노란색-주황색에서 주황색-갈색
수용성
불용성
안정성
안정적인. 강한 산화제와 호환되지 않습니다.
주요 응용
화학적 기계적 연마, 리포솜 안정화, 세포 운동성 분석, 핵산 검출, 바이러스 검출, 위 점막 안전성 스크리닝, 다약제 내성 억제제, 약물 전달, 동맥경화반 영상화
EPA
Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl)bis(methylene)]bis[N-(carboxymethyl)- (1461-15-0)

화학적 성질

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 5건

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral];H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal];H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation];H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 2건

Chemical: Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl)bis(methylene)]bis[N-(carboxymethyl)-

Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl)bis(methylene)]bis[N-(carboxymethyl)-: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryMay cause mechanical eye irritation; [Acros Organics MSDS] See Fluorescein.
Hazard Classes and CategoriesAcute Tox. 4 (100%);Acute Tox. 4 (100%);Skin Irrit. 2 (100%);Eye Irrit. 2 (100%);Acute Tox. 4 (100%);STOT SE 3 (100%)

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 2건

Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)

용도 및 제조

General Manufacturing InformationGlycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl)bis(methylene)]bis[N-(carboxymethyl)-: ACTIVE

응용 분야

용도Calcein is used for determination of Ca in biological systems. Indicator for the fluorimetric determination of calcium in presence of Mg by complexometric titration.

공급사100 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]

관련 반응

1건
반응 기록 만들기
HRID 1250440 반응식
HRID 1250440반응물로uspto-grants-2002_01

화합물 노트

불러오는 중…

이 페이지에서기본 정보이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
1461-15-0
PubChem CID
65079
ChEMBL
CHEMBL1973733
ChEBI
CHEBI:51903
UNII
V0YM2B16TS
EC Number
215-957-1
Nikkaji
J7.743G

orange crystals

규제 정보

Regulatory Information · 2건

Chemical: Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl)bis(methylene)]bis[N-(carboxymethyl)-

Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl)bis(methylene)]bis[N-(carboxymethyl)-: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk
3
tsca
TSCA listed
HS 번호
32041900
risk_code
20/21/22-36/37/38
hazard_code
Xn
safety_code
22-24/25-36/37/39-26
F 고인화성물질
10
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