D-시로-이노시톨, 3-O[2-아미노-4-[(카르복시미노메틸)아미노]-2,3,4,5-테트라디옥시-a-D-아라비노-헥소파이라노실]-

개요Trade names: “Kasugamin,” “Kasumin” Patent: JP 42006818; BE 657659: GB 1094566. Systemic fungicide and bactericide with protective and curative action. Controls rice blast caused by Pyricularia oryzae and other rice diseases, such as bacterial grain rot, bacterial seedling blight, and bacterial brown stripe caused by Pseudomonas spp. (15). Effective on other plant diseases, e.g., leaf mold and bacterial canker in tomatoes, bean halo blight, scab on apples, Cercospora spp. leaf spot on sugar beet, and bacterial soft rot on potatoes.

용도Kasugamycin is an antibiotic aminoglycoside that inhibits protein synthesis.

일반 설명Kasugamycin was found in the culture broth of Streptomyces kasugaensis by Umezawa et al. in 1965. It has an aminocyclitol structure and shows strong activity against phytopathogenic fungi, especially Pericularia oryzae, the pathogen causing rice blast. This drug also shows activity against Pseudomonas, and its toxicity is very low; no mice died following intravenous injection of doses as high as two grams per kilogram. Kasugamycin has been used to protect rice plants against rice blast and for animal infections.