기본 정보
- CAS
31828-50-9- 표준 SMILES
CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)C3=CCC=CC3)[C@H]2SC1.O.O- InChIKey
HBKDHIDYMXXJLI-OEDJVVDHSA-N- 분자식
- C16H23N3O6S
- 평균 분자량
- 385.4 g/mol
- 단동위원소 질량
- 385.13075664
개요
Cephradine Dihydrate is the dihydrate form of cephradine, a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephradine dihydrate binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
이름 및 식별자
- 우선 이름
- Cephradine Dihydrate
- IUPAC
- (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;dihydrate
- 현지명
- 세프라딘(200MG)
- 영어명
- CEPHRADINE (200 MG)
- 분자식
- C16H23N3O6S
- 분자량
- 0
이름 및 동의어
Cephradine dihydrate31828-50-956PPJ9MMPESQ 22022DTXSID90185698RefChem:124434DTXCID30108189Cefradin hydrate(6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;dihydrateVelosef hydrateSefril hydrate58456-86-3
이름 더 보기
세프라딘(200MG)SQ-22022CEPHRADINE (200 MG)Cephradine (1102805)(6R,7R)-7-[[2-amino-2-(1-cyclohexa-1,4-dienyl)acetyl]amino]-3-methyl-8 -oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrate
UNII-56PPJ9MMPECEFRADINE DIHYDRATESCHEMBL719332orb1740026CEPHRADINE DIHYDRATE [MI]DTXSID50974005HBKDHIDYMXXJLI-OEDJVVDHSA-NAKOS026749823
데이터베이스 식별자
- CAS
31828-50-9、58456-86-3- PubChem CID
물성
구조 계산 물성
- 극성 표면적
- 140 Ų
- 수소 결합 공여자 수
- 5
- 수소 결합 수용자 수
- 8
- 회전 가능 결합 수
- 4
- 무거운 원자 수
- 26
- 형식 전하
- 0
- 복잡도
- 697
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Danger
H315 (40%): Causes skin irritation [Warning Skin corrosion/irritation]
P233, P260, P261, P264, P264+P265, P271, P272, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 5 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Hazard Classes and CategoriesSkin Irrit. 2 (40%)
화학 및 산업
약리 정보
MeSH Pharmacological ClassificationSubstances that inhibit the growth or reproduction of BACTERIA.
공급사1 곳
国药集团化学试剂有限公司86-21-63210123 · [email protected]
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