Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Betamethasone Sodium Phosphate
BETAMETHASONE SODIUM PHOSPHATE · BETAMETHASONE 21-DISODIUM PHOSPHATE · Durabetason · betnesol · bentelan · BETAMETHASONE 21-PHOSPHATE DISODIUM SALT · Celestan · Bentalan
식별자 및 물리적 특성
| CAS No. | 151-73-5 |
|---|---|
| 분자식 | C22H28FNa2O8P |
| 평균 분자량 | 516.4 g/mol |
| 단동위원소 질량 | 516.13012157 g/mol |
| SMILES | C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COP(=O)([O-])[O-].[Na+].[Na+] |
| InChIKey | PLCQGRYPOISRTQ-LWCNAHDDSA-L |
| PubChem CID | 65478 |
| ChEMBL | CHEMBL1200762 |
| ChEBI | CHEBI:3078 |
| EC No. | 205-797-0 |
| DTXSID | DTXSID8047137 |
화학 및 물리적 성질
| 극성 표면적 | 147 |
|---|---|
| 수소 결합 공여자 수 | 2 |
| 수소 결합 수용자 수 | 9 |
| 회전 가능 결합 수 | 3 |
| 무거운 원자 수 | 34 |
| 형식 전하 | 0 |
| 복잡도 | 961 |
| 녹는점 | 206-211°C |
| 저장 조건 | room temp |
| 용해도 | 물에 잘 녹고, 에탄올(96%)에 약간 녹으며, 염화메틸렌에는 거의 녹지 않습니다. |
| 물리적 상태 | Solid |
| 색상 | 흰색에서 황백색까지 |
| pH | 7.5~9.0(5g/l, 25℃) |
| 용해도 | water: 50mg/mL, clear to very slightly hazy, faintly yellow |
| Merck | 14,1180 |
| 안정성 | 흡습성 |
| InChIKey | PLCQGRYPOISRTQ-LWCNAHDDSA-L |
| SMILES | [C@@]12([H])C[C@H](C)[C@](O)(C(=O)COP([O-])([O-])=O)[C@@]1(C)C[C@H](O)[C@]1(F)[C@@]3(C)C=CC(=O)C=C3CC[C@@]21[H].[Na+].[Na+] |&1:0,3,5,15,18,20,22,32,r| |
| EPA | .beta.-Methasone disodium phosphate (151-73-5) |
화학적 성질
White or almost white powder, very hygroscopic.
안전 및 규제
| GHS 분류 | DangerH302 (44.2%): Harmful if swallowed [Warning Acute toxicity, oral]H330 (54.9%): Fatal if inhaled [Danger Acute toxicity, inhalation]H360 (42.5%): May damage fertility or the unborn child [Danger Reproductive toxicity]H360D (15%): May damage the unborn child [Danger Reproductive toxicity]H372 (48.7%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]H373 (12.4%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]H410 (46.9%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]P203, P260, P264, P270, P271, P273, P280, P284, P301+P317, P304+P340, P316, P318, P319, P320, P330, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 113 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| 규제 정보 | Betamethasone sodium phosphate: Does not have an individual approval but may be used under an appropriate group standard |
| 기타 안전 정보 | IMAP assessments - Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11.beta.,16.beta.)-: Environment tier I assessmentIMAP assessments - Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11.beta.,16.beta.)-: Human health tier I assessment |
| Hazard Classes and Categories | Acute Tox. 4 (44.2%)Acute Tox. 2 (54.9%)Repr. 1B (42.5%)Repr. 1B (15%)STOT RE 1 (48.7%)STOT RE 2 (12.4%)Aquatic Chronic 1 (46.9%) |
| 수질 위해 등급(WGK) | 3 |