Oxetane, 3,3-bis(chloromethyl)-｜Huagongshe

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HCID 6550생성일: 2026년 10월 27일

Oxetane, 3,3-bis(chloromethyl)-

https://huagongshe.com/ko/chemical/6550

Oxetane, 3,3-bis(chloromethyl)- 분자 구조식

식별자 및 물리적 특성

CAS No.	25323-58-4
분자식	C5H8Cl2O
평균 분자량	155.02 g/mol
단동위원소 질량	153.99522024 g/mol
SMILES	ClCC1(CCl)COC1
InChIKey	CXURGFRDGROIKG-UHFFFAOYSA-N
PubChem CID	6550
ChEMBL	CHEMBL1988189
EC No.	201-136-5
DTXSID	DTXSID9058816

화학 및 물리적 성질

XLogP	1.1
극성 표면적	9.2
수소 결합 공여자 수	0
수소 결합 수용자 수	1
회전 가능 결합 수	2
무거운 원자 수	8
형식 전하	0
복잡도	74.5
물질 분류	Other Classes -> Other Organic Compounds
SpringerMaterials Properties	Fusion temperature
밀도	1.41.4 @25 °C
Color/Form	Finely divided powder for coatingsNatural, black, or olive green molding powder.
끓는 점	217 °F at 30 mmHg (EPA, 1998)200 °C @760 [mm Hg]
녹는점	66 °F (EPA, 1998)18.7 °C
증기압	0.5 [mm Hg] @25 °C
Food Contact Substances	FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical Description	The monomer unit of a thermoplastic resin trademarked Penton.Natural, black, or olive green solid[HSDB] "The monomer unit of a thermoplastic resin trademarked Penton. " mp = 18.9 deg C[CAMEO] Liquid[MSDSonline]
Other Experimental Properties	A linear polymer extremely resistant to chemicals and to thermal degradation at molding and extrusion temperature ... dimensionally stable, very low water absorption.

안전 및 규제

Protective Action Criteria (PAC)
GHS 분류	WarningH302 (97.5%): Harmful if swallowed [Warning Acute toxicity, oral]P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 40 reports by companies from 2 notifications to the ECHA C&L Inventory.
화재 가능성	Self extinguishing
유해성 요약	Causes somnolence in lethal-dose feeding studies of ratsCauses lacrimation, somnolence, and kidney damage in high-dose inhalation studies[RTECS] An irritant and lachrymatorHighly toxic by inhalationTargets blood, kidneys, and CNS[Aldrich MSDS]
반응성 그룹	Ethers
Reactivity Profile	3,3-BIS(CHLOROMETHYL)OXETANE is a chlorinated ether.
Air and Water Reactions	No rapid reaction with air. No rapid reaction with water.
CERCLA 보고 수량	Releases of CERCLA hazardous substances are subject to the release reporting requirement of CERCLA section 103, codified at 40 CFR part 302, in addition to the requirements of 40 CFR part 355. Oxetane, 3,3-bis(chloromethyl)- is an extremely hazardous substance (EHS) subject to reporting requirements when stored in amounts in excess of its threshold planning quantity (TPQ) of 500 lbs.
Hazard Classes and Categories	Acute Tox. 4 (97.5%)
응급 처치	Signs and Symptoms of Oxetane, 3,3-Bis(chloromethyl)- Exposure: Signs and symptoms of acute exposure to oxetane, 3,3-bis(chloromethyl)- may include headache, dizziness, weakness and nausea. Also, irritation of the eyes, skin, respiratory tract may be observed. Esophagus or gastrointestinal tract irritation is possible if ingested. Longer term exposure may lead to allergic hypersensitivity dermatitis or asthma with bronchospasm and wheezing.
정리 방법	Purification of waste water from the synthesis of 3,3-di-(chloromethyl) oxycyclobutane.Biological clarification of sewage from production of 3,3-bis(chloromethyl) oxycyclobutane.

Personal Protective Equipment (PPE)	For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)

Non-Human Toxicity Excerpts

A series of oxetanes containing iodomethyl, alkoxymethyl, and alkylaminomethyl groups were synthesized. The toxicity and broncholytic activity of these compounds were determined in mice and cats. Iodo- and alkyloxy-containing oxetanes possessed lower toxicity, and N-containing oxetanes had higher toxicity than 3,3-bis(chloromethyl)oxetane, the initial product of the synthesis. All compounds containing oxetane ring manifested a pronounced broncholytic effect. 3-(Chloromethyl)-3-(butoxymethyl)oxetane, 3,3-bis(propoxymethyl)oxetane, and 3-(chloromethyl)-3-(iodomethyl)oxetane possessed the same broncholytic effect, as that of euphyllin.