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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HCID 65864생성일: 2026년 10월 26일

Flomoxef

FMOX · Flumarin · FLOMOXEF · FLOMOEXF · Flomoxef Acid · Flomoxef Monomer · Flomoxef USP/EP/BP · Flomoxef Acid(Sodium)

https://huagongshe.com/ko/chemical/65864

Flomoxef 분자 구조식

식별자 및 물리적 특성

CAS No.99665-00-6
분자식C15H18F2N6O7S2
평균 분자량496.5 g/mol
단동위원소 질량496.06464536 g/mol
SMILESCO[C@@]1(NC(=O)CSC(F)F)C(=O)N2C(C(=O)O)=C(CSc3nnnn3CCO)CO[C@@H]21
InChIKeyUHRBTBZOWWGKMK-DOMZBBRYSA-N
PubChem CID65864
ChEMBLCHEMBL15413
ChEBICHEBI:135813
DTXSIDDTXSID5048845

화학 및 물리적 성질

XLogP-1.3
극성 표면적220
수소 결합 공여자 수3
수소 결합 수용자 수14
회전 가능 결합 수11
무거운 원자 수32
형식 전하0
복잡도793
의약품Pharmaceuticals -> Anti infectives for systemic use -> Antibacterials for systemic usePharmaceuticals -> Listed in ZINC15Pharmaceuticals -> Antibiotics
녹는점82.5-87.5°
밀도1.85±0.1 g/cm3(Predicted)
저장 조건Store at -20°C
용해도메탄올,DMSO에 용해됨
물리적 상태고체
pKa(산도 계수)3.26±0.40(Predicted)
색상회백색
InChIKeyUHRBTBZOWWGKMK-DOMZBBRYSA-N
SMILESN12[C@@]([H])([C@@](NC(CSC(F)F)=O)(OC)C1=O)OCC(CSC1N(CCO)N=NN=1)=C2C(O)=O

안전 및 규제

Drug Induced Liver InjuryDrug-Induced Liver Injury Severity and Toxicity (DILIst)FlomoxefDILI PositiveDOI:10.1016/j.drudis.2019.09.022

용도

개요

Flomoxef sodium is a P-lactamase resistant oxacephalosporin. Its spectrum of activity is similar to that of cefazolin and moxalactam, but with better efficacy against Staphylococcus aureus and Bacteroides fragilis. Flomoxef is reported effective in the treatment of post-operative, urinary tract and abdominal cavity infections.

용도

Flomoxef is an oxacephem derived beta-lactam antibiotic that is particularly effective against gram-positive bacteria.