2-Amino-5-chloropyridine (HCID 66174)

개요

structure given in first source

이름 및 식별자

우선 이름: 2-Amino-5-chloropyridine
IUPAC: 5-chloropyridin-2-amine
영어명: 2-Amino-5-chloropyridine
분자식: C5H5ClN2
분자량: 128.56

이름 및 동의어

2-Amino-5-chloropyridine1072-98-65-Chloro-2-pyridinamine2-Pyridinamine, 5-chloro-NSC-26283J8TAP6NFD4DTXSID0073247RP-26695RefChem:464572DTXCID8033063214-020-45-chloropyridin-2-amine

이름 더 보기

80.8AKOS 91155TIMTEC-BB SBB0000595-Chlor-2-pyridylamin5-CHLORO-A-PYRIDYLAMINE2-Amino-5-Cloropyridine

5-Chloro-2-pyridylamine5-Chloro-2-aminopyridinePyridine, 2-amino-5-chloro-MFCD000063245-chloropyridin-2-ylamineA1I732-amino-5-chloro pyridine5-chloro-pyridin-2-ylamine

데이터베이스 식별자

CAS: 1072-98-6
PubChem CID: 66174
DTXSID: DTXSID0073247
UNII: J8TAP6NFD4
EC Number: 214-020-4
Nikkaji: J31.385H

물성

구조 계산 물성

XLogP: 1.1
극성 표면적: 38.9 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 2
회전 가능 결합 수: 0
무거운 원자 수: 8
형식 전하: 0
복잡도: 76.8

실험 및 물리화학적 성질

Chemical ClassesNitrogen Compounds -> Pyridines

SpringerMaterials PropertiesNuclear quadrupole resonance spectroscopy

Physical DescriptionBeige crystalline solid; [Sigma-Aldrich MSDS]

물리화학적 성질

녹는점: 135 · 135-138 °C (lit.)
끓는 점: 127 · 127-128 °C/11 mmHg (lit.)
밀도: 1.2417 · 1.2417 (rough estimate)
굴절률: 1.511 · 1.5110 (estimate)
인화점: 160 °C · 160 °C
저장 조건: 2 · 2-8°C
용해도: 1 g/L · 1.0g/L
산도 계수 (pKa): 4.67 · 4.67±0.13(Predicted)
물리적 상태: 결정성 분말
색상: 베이지~베이지 브라운
수용성: 1 g/L · 1g/L(20℃)
BRN: 108735 · 108735
InChI: 1S/C5H5ClN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)
InChIKey: MAXBVGJEFDMHNV-UHFFFAOYSA-N
SMILES: Nc1ccc(Cl)cn1
NIST: 2 · 2-Amino-5-chloropyridine(1072-98-6)
EPA: 2 · 2-Amino-5-chloropyridine (1072-98-6)

화학적 성질

beige to beige-brown crystalline powder

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 63 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 2건

Status: Active Update: 05-06-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/18254

2-Pyridinamine, 5-chloro-: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryMay cause irritation; Harmful by ingestion; [Sigma-Aldrich MSDS]

Hazard Classes and CategoriesAcute Tox. 4 (100%)

안전 데이터

wgk: 3
HS 번호: 29333999
risk_code: 22-36/37/38
hazard_code: Xn,Xi
safety_code: 22-24/25-37/39-26-36
위험 등급: IRRITANT
위험 참고 사항: Harmful
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

응용 분야

용도5-Chloro-2-pyridinamine is a useful synthetic intermediate. It can be used to synthesize zopiclone (Z700500) which is a cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists.

상·하류 제품 정보

하류 제품

Zopiclone 5-Chloro-2-hydroxy-3-nitropyridine 2,5-Dichloro-3-nitropyridine 2,5-Dichloropyridin-3-amine ethyl 2-(6-aminopyridin-3-yl)acetate 6-클로로-[1,2,4]트리아졸로[1,5-a]피리딘-2-아민 EthanediaMide iMpurity F 2-Bromo-5-chloropyridine 2-Bromo-5-chloro-3-nitropyridine 2-Amino-5-chloro-3-nitropyridine 3-AMINO-2-BROMO-5-CHLOROPYRIDINE 5-Chloropyridine-2-carboxylic acid

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

上海泰矶林实业有限公司02150630626 17717886015 · [email protected]

INTATRADE GmbH+49 3493/605464 · [email protected]

연결된 노트

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2-Amino-5-chloropyridine

기본 정보

개요