메틸글리콜레이트

Methyl Glycolate

HCID 66774CAS 96-35-5
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기본 정보

표준 SMILES
COC(=O)CO
InChIKey
GSJFXBNYJCXDGI-UHFFFAOYSA-N
분자식
C3H6O3
평균 분자량
90.08 g/mol
단동위원소 질량
90.03169405

개요

Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Methyl Glycolate...

이름 및 식별자

우선 이름
Methyl Glycolate
IUPAC
methyl 2-hydroxyacetate
현지명
메틸글리콜레이트
영어명
Methyl glycolate
분자식
C3H6O3
분자량
90.08

이름 및 동의어

Methyl glycolate96-35-5Methyl hydroxyacetateAcetic acid, hydroxy-, methyl esterGlycolic acid, methyl esterAcetic acid, 2-hydroxy-, methyl ester7G7R729EJ0NSC-27786DTXSID3059131RefChem:157882DTXCID4048981202-502-7
이름 더 보기
메틸글리콜레이트MGMethylglycolate,98%Hydroxy acetateMethyleglycolate2-hydroxyethanoateGlycolic acid methyl
methyl 2-hydroxyacetateMFCD00004667Hydroxyacetic Acid Methyl Ester2-hydroxyacetic acid methyl esterGlycolic Acid Methyl EsterMethyl 2-hydroxyethanoate124238-96-6EINECS 202-502-7

데이터베이스 식별자

CAS
96-35-5
PubChem CID
66774
DTXSID
DTXSID3059131
UNII
7G7R729EJ0
EC Number
202-502-7
Nikkaji
J3.969A

물성

구조 계산 물성

XLogP
-0.5
극성 표면적
46.5 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
3
회전 가능 결합 수
2
무거운 원자 수
6

실험 및 물리화학적 성질

Chemical ClassesOther Classes -> Esters, Other
CosmeticsCosmetic ingredients (Methyl Glycolate) -> CIR (Cosmetic Ingredient Review)
SpringerMaterials PropertiesCoriolis coupling
Physical DescriptionClear light yellow liquid; [Sigma-Aldrich MSDS]

물리화학적 성질

녹는점
149 · 149-151 °C
끓는 점
149 · 149-151 °C(lit.)
밀도
1.167 g/mL · 1.167 g/mL at 25 °C(lit.)
증기 밀도
3.12 · 3.12 (vs air)
증기압
17 mm · 17 mm Hg ( 52 °C)
굴절률
20 · n20/D 1.417(lit.)

화학적 성질

Clear colorless liquid

안전 및 규제

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 16.7% (1 of 6) of reports.

Warning

H227 (33.3%): Combustible liquid [Warning Flammable liquids]

P210, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 6 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory InformationAcetic acid, hydroxy-, methyl ester: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryMay cause irritation; [Sigma-Aldrich MSDS]
Hazard Classes and CategoriesFlam. Liq. 4 (33.3%)

독성 정보

Toxicity Summary · 2건

Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Methyl Glycolate...

Safe for use in cosmetics, with qualifications

안전 데이터

wgk
3
tsca
TSCA listed
HS 번호
29181990
risk_code
36/37/38
hazard_code
Xi
safety_code
23-24/25

화학 및 산업

용도 및 제조

UsesCIR ingredient: Methyl Glycolate
General Manufacturing InformationAcetic acid, 2-hydroxy-, methyl ester: ACTIVE
응용 분야 · 2건

용도Methyl glycolate is a chemical reagent used in the synthesis of taxol and rapamycin. It is used in leather tanning and textile dyeing. It acts as a flavoring agent, preservative in food processing, in water treatment industries and as chemical intermediates. Further, it is used in emulsion polymers, ink and paint additive to improve flow properties and impart gloss. It plays an important role in producing triisopropylsilanyloxy-acetic acid methyl ester using imidazole as reagent.

일반 설명Synthesis of methyl glycolate from the carbonylation of HCHO using heteropoly acids (HPAs) as catalysts, followed by esterification with methanol was reported. Size-selective vibrational spectroscopy of methyl glycolate clusters was reported.

상·하류 제품 정보

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]

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