4-클로로프탈릭 무수물
4-클로로프탈릭무수물 · 4-클로로프탈산무수물 · 5-Chloroisobenzofuran-1,3-dione · CHLOROPHTHALIC ANHYDRIDE · 4-Chlorophthalic · Chlorophtalicanhydre,95% · 4-Chlorophtalic anhydride · 4-Chlorophthalic anhydrid
식별자 및 물리적 특성
| CAS No. | 118-45-6 |
|---|---|
| 분자식 | C8H3ClO3 |
| 평균 분자량 | 182.56 g/mol |
| 단동위원소 질량 | 181.97707164 g/mol |
| SMILES | O=C1OC(=O)c2cc(Cl)ccc21 |
| InChIKey | BTTRMCQEPDPCPA-UHFFFAOYSA-N |
| PubChem CID | 67044 |
| EC No. | 204-251-9 |
| DTXSID | DTXSID30151993 |
| 현지명 | 4-클로로프탈릭 무수물 |
화학 및 물리적 성질
| XLogP | 1.9 |
|---|---|
| 극성 표면적 | 43.4 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 3 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 12 |
| 형식 전하 | 0 |
| 복잡도 | 238 |
| 녹는점 | 96°C |
| 끓는 점 | 290 °C |
| 밀도 | 1.594±0.06 g/cm3(Predicted) |
| 증기압 | 0.058-0.058Pa at 25℃ |
| 저장 조건 | under inert gas (nitrogen or Argon) at 2-8°C |
| 용해도 | 톨루엔에 용해됨 |
| 물리적 상태 | Solid:particulate/powder |
| 색상 | 흰색에서 거의 흰색 |
| InChI | InChI=1S/C8H3ClO3/c9-4-1-2-5-6(3-4)8(11)12-7(5)10/h1-3H |
| InChIKey | BTTRMCQEPDPCPA-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=C(Cl)C=C2)C(=O)O1 |
| LogP(분배 계수) | 2.713 |
화학적 성질
4-Chlorophthalic anhydride has a melting point of around 99 °C. Like most acid anhydrides, it can hydrolyze in the presence of water.
안전 및 규제
| GHS 분류 | DangerH315 (57.1%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 7 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 규제 정보 | Regulation (EC) No 1935/2004 (amended)PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.Status: Cease Manufacture Update: 18-05-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/12546 |
| Hazard Classes and Categories | Skin Irrit. 2 (57.1%) |
| TSCA 등재 상태 | TSCA listed |
| 관세 코드 | 2932990090 |
| 위험 문구(R) | 36/37/38 |
| 안전 문구(S) | 26-36/37/39 |
용도
용도
4-chlorophthalic anhydride is an important monomer synthesis of polyimide and polyimide is considered to be the highest tolerance has been industrialized in the polymer and the shape and chemical stability of other materials can not like the outburst strength, wear resistance and extreme temperatures, excellent, has been widely used in aviation, aerospace, microelectronics and atom to the field of high technology. 4- of 4-chlorophthalic anhydride is mainly used in the synthesis of diphenyl ether dianhydride anhydride, two single and two double ether, thioether dianhydride anhydride two, two, and two amine polymerization ring was a series of polyimide engineering plastic with excellent performance. 4- of 4-chlorophthalic anhydride is not only the ideal raw material for the synthesis of various intermediates of polyimide, and can be used as a drug or pesticide.
제조 및 합성 방법
제조 방법
A preparation method of 4-chlorophthalic anhydride uses monosodium phthalic acid as a raw material, uses water as a medium, uses a weak alkali solution as a pH regulator of a reaction system, and directly performs chlorination reaction with chlorine gas. The weak alkali solution is used as the pH regulator of the reaction system, which is beneficial to stabilizing the pH value of the reaction system, and can obtain high-yield 4-chlorophthalic acid monosodium coarse salt. The crude salt is desalted, dehydrated and closed to obtain a crude product of 4-chlorophthalic anhydride, which is purified by rectification to obtain high-purity 4-chlorophthalic anhydride.