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2-플루오로바이페닐

2-Fluorobiphenyl

HCID 67579
노트반응

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기본 정보이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
321-60-8
표준 SMILES
Fc1ccccc1-c1ccccc1
InChIKey
KLECYOQFQXJYBC-UHFFFAOYSA-N
분자식
C12H9F
평균 분자량
172.2 g/mol
단동위원소 질량
172.06882845

이름 및 식별자

우선 이름
2-Fluorobiphenyl
IUPAC
1-fluoro-2-phenylbenzene
현지명
2-플루오로바이페닐
영어명
2-Fluorobiphenyl
분자식
C12H9F
분자량
172.2

이름 및 동의어

2-Fluorobiphenyl321-60-82-Fluoro-1,1'-biphenylo-FluorodiphenylBiphenyl, 2-fluoro-1,1'-Biphenyl, 2-fluoro-ortho-FluorodiphenylCCRIS 1659DTXSID5047744EINECS 206-290-7NSC 10366DTXCID5027728
이름 더 보기
2-플루오로바이페닐2-플루오로비페닐Fluorobiphenyl48722-u2-Fluorobiphen2-FLUORODIPHENYL2-fluoro-biphenyo-Fluorobiphenyl
oFluorodiphenylorthoFluorodiphenylBiphenyl, 2fluoroFluorobiphenyl, 22Fluoro1,1'biphenylRefChem:4726211,1'Biphenyl, 2fluoro206-290-7

데이터베이스 식별자

CAS
321-60-8
PubChem CID
67579
DTXSID
DTXSID5047744
ChEMBL
CHEMBL122521
UNII
KC8Q87V4QY
EC Number
206-290-7
Nikkaji
J27B

물성

구조 계산 물성보충 중

XLogP
4
극성 표면적
0 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
1
회전 가능 결합 수
1
무거운 원자 수
13
형식 전하
0
복잡도
149

실험 및 물리화학적 성질

Density1.2452 at 77 °F (NTP, 1992) - Denser than water; will sink
Boiling Point478 °F at 760 mmHg (NTP, 1992)
Melting Point164.3 °F (NTP, 1992)
Physical Description · 2건

2-fluorobiphenyl appears as colorless crystals.

Colorless solid; [CAMEO] Off-white crystalline powder; [Alfa Aesar MSDS]

Kovats Retention Index · 3건

1346;232.03

1346;231.69;233.5

226.44

물리화학적 성질

녹는점
71 · 71-74 °C (lit.)
끓는 점
248 °C · 248 °C (lit.)
밀도
1 · 1,245 g/cm3
굴절률
1.5678 · 1.5678 (estimate)
인화점
248 °C · 248°C
저장 조건
Sealed in dry,Room Temperature
용해도
클로로포름(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
powder to crystal

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 28.6% (2 of 7) of reports.

Danger

H302 (14.3%): Harmful if swallowed [Warning Acute toxicity, oral];H315 (71.4%): Causes skin irritation [Warning Skin corrosion/irritation];H318 (14.3%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H319 (57.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (71.4%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H400 (28.6%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard];H410 (14.3%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 7 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 2 of 7 reports by companies.;There are 4 notifications provided by 5 of 7 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

DOT LabelClass 9
Fire Hazards · 1건

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:;Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot. For UN3508, Capacitor, asymmetric, be aware of possible short circuiting as this product is transported in a charged state. Polymeric beads, expandable (UN2211) may evolve flammable vapours. (ERG, 2024)

화학 및 산업

용도 및 제조

General Manufacturing Information1,1'-Biphenyl, 2-fluoro-: ACTIVE
응용 분야 · 2건

용도2-Fluorobiphenyl is used as pharmaceuticals, veterinary drugs and organic synthesis intermediates. 2-Fluorobiphenyl was used as an internal standard for analysis of environmental pollutants in sediments using pressurized liquid extraction and gas chromatography-mass spectrometry, as a sole carbon & energy source for P. pseudoalcaligenes.

일반 설명Colorless crystals.

상·하류 제품 정보

상류 원료

Methanesulfonic acid, 1,1,1-trifluoro-, [1,1'-biphenyl]-2-yl esterBenzenediazonium, 2-fluoro-, tetrafluoroborate(1-)페닐트리알릴실란4-브로모-2-플루오로비페닐테트라페닐붕산 나트륨

하류 제품

FLURBI프로FEN1-[2'-fluoro(1,1'-biphenyl)-4-yl]ethan-1-one

공급사100 곳

관련 반응

23건
반응 기록 만들기
HRID 98603 반응식
HRID 98603반응물로Training data from https://doi.org/10.1039/C8SC04228D (2/10)
HRID 167660 반응식
HRID 167660반응물로Training data from https://doi.org/10.1039/C8SC04228D (9/10)
HRID 173451 반응식
HRID 173451반응물로Training data from https://doi.org/10.1039/C8SC04228D (9/10)
HRID 173636 반응식
HRID 173636반응물로Training data from https://doi.org/10.1039/C8SC04228D (9/10)
HRID 264774 반응식
HRID 264774반응물로uspto-grants-1997_07
HRID 381831 반응식
HRID 381831반응물로uspto-grants-2001_10
HRID 808794 반응식
HRID 808794반응물로Test data from https://doi.org/10.1039/C8SC04228D
HRID 838238 반응식
HRID 838238반응물로Test data from https://doi.org/10.1039/C8SC04228D
1 / 3 페이지

화합물 노트

불러오는 중…

이 페이지에서기본 정보이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
색상
흰색에서 밝은 노란색
수용성
알코올, 에테르에 용해됩니다. 물에 불용성.
BRN
2043175 · 2043175
안정성
안정적인. 강한 산화제와 호환되지 않습니다. 타기 쉬운.
InChI
1S/C12H9F/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9H
InChIKey
KLECYOQFQXJYBC-UHFFFAOYSA-N
SMILES
Fc1ccccc1-c2ccccc2
NIST
1 · 1,1'-Biphenyl, 2-fluoro-(321-60-8)
EPA
2 · 2-Fluorobiphenyl (321-60-8)

화학적 성질

Off-white Crystalline powder

Health Hazards · 1건

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:;Inhalation of material may be harmful. Contact may cause burns to skin and eyes. Inhalation of Asbestos dust may have a damaging effect on the lungs. Fire may produce irritating, corrosive and/or toxic gases. Some liquids produce vapors that may cause dizziness or asphyxiation. Runoff from fire control or dilution water may cause environmental contamination. (ERG, 2024)

Hazards SummaryMay cause irritation; [Alfa Aesar MSDS] See Biphenyl.
Reactive GroupAryl Halides
Reactivity Profile · 1건

Simple aromatic halogenated organic compounds, such as 2-FLUOROBIPHENYL, are very unreactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Air and Water ReactionsInsoluble in water.
Hazard Classes and CategoriesAcute Tox. 4 (14.3%);Skin Irrit. 2 (71.4%);Eye Dam. 1 (14.3%);Eye Irrit. 2 (57.1%);STOT SE 3 (71.4%);Aquatic Acute 1 (28.6%);Aquatic Chronic 1 (14.3%)

안전 및 보호

Fire Fighting · 1건

This compound is not very flammable but any fire involving this compound may produce dangerous vapors. You should evacuate the area. All firefighters should wear full-body protective clothing and use self-contained breathing apparatuses. You should extinguish any fires involving this chemical with a dry chemical, carbon dioxide, foam, or halon extinguisher. (NTP, 1992)

First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.;SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.;INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.;INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: You should dampen the solid spill material with acetone, then transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the adsorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a strong soap and water solution. Do not reenter the contaminate area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.;STORAGE PRECAUTIONS: You should protect this material from exposure to light, and store it in a refrigerator. (NTP, 1992)

Isolation and Evacuation · 1건

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:;IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.;SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.;FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Personal Protective Equipment (PPE) · 1건

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.;RECOMMENDED GLOVE MATERIALS: Permeation data indicate that Viton gloves may provide protection to contact with this compound. Viton over latex gloves is recommended. However, if this chemical makes direct contact with your gloves, or if a tear, hole or puncture develops, remove them at once. (NTP, 1992)

독성 정보

EPA Provisional Peer-Reviewed Toxicity Values · 3건

2-Fluorobiphenyl

PDF Document

2004

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
DV5291000
ridadr
UN 1593 6.1/PG 3
HS 번호
29036990
risk_code
36/37/38-63-43-23/24/25-45-40-50/53-41-37/38-22-52/53
hazard_code
Xi,T,Xn,N
safety_code
22-24/25-36/37/39-36/37-23-53-61-60-39-26
위험 등급
IRRITANT
스토리지 클래스
11 - Combustible Solids
함량 및 규제정보
물질구분: 유독물질; 혼합물(제품)함량정보: 2-플루오로-1,1'-비페닐[2-Fluoro-1,1'-biphenyl; 321-60-8] 및 이를 25% 이상 함유한 혼합물
유해화학물질 필터링
2019-1-949(신규화학물질)
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