아버멕틴B1b

아버멕틴B1b · AbaMectin B1b · C-076B1b · avermectin b1b · Aviparazine B1b · Antibiotic C-076B1b · Abamectin B1b (~90%) · Dolamectin Impurity 2

식별자 및 물리적 특성

CAS No.	65195-56-4
분자식	C47H70O14
평균 분자량	859 g/mol
단동위원소 질량	858.47655692 g/mol
SMILES	CO[C@H]1C[C@H](O[C@H]2[C@H](C)O[C@@H](O[C@@H]3/C(C)=C/C[C@@H]4C[C@@H](C[C@]5(C=C[C@H](C)[C@@H](C(C)C)O5)O4)OC(=O)[C@@H]4C=C(C)[C@@H](O)[C@H]5OC/C(=C\C=C\[C@@H]3C)[C@]54O)C[C@@H]2OC)O[C@@H](C)[C@@H]1O
InChIKey	ZFUKERYTFURFGA-PVVXTEPVSA-N
PubChem CID	6858005
ChEMBL	CHEMBL2079552
ChEBI	CHEBI:29537
EC No.	265-611-9
DTXSID	DTXSID4058239
현지명	아버멕틴B1b

XLogP	3.5
극성 표면적	170
수소 결합 공여자 수	3
수소 결합 수용자 수	14
회전 가능 결합 수	7
무거운 원자 수	61
형식 전하	0
복잡도	1,710
의약품	Pharmaceuticals -> Antibiotics
지질	Polyketides [PK] -> Macrolides and lactone polyketides [PK04]
농약	Acaricides, Insecticides
끓는 점	934.6±65.0 °C(Predicted)
밀도	1.25±0.1 g/cm3(Predicted)
저장 조건	Store at -20°C
용해도	DMSO에 용해됨
물리적 상태	고체
pKa(산도 계수)	12.42±0.70(Predicted)
색상	하얀색
안정성	Unstable in Solution, Very Hygroscopic
InChIKey	ZFUKERYTFURFGA-VMROQZAPNA-N
EPA	Avermectin B1b (65195-56-4)

GHS 분류	DangerH300+H330 (96.6%): Fatal if swallowed or if inhaled [Danger Acute toxicity, oralacute toxicity, inhalation]P203, P260, P262, P264, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P316, P318, P319, P320, P321, P330, P361+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 29 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard Classes and Categories	Acute Tox. 2 (100%)
건강 영향	Avermectins are neurotoxic and have reproductive and developmental effects. (L1826)
독성 요약	It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chloride channels, reducing membrane resistance and increasing conductance inward. (T10)
Signs and Symptoms	Avermectins cause irritation of skin and eyes, central nervous system depression (incoordination, tremors, lethargy, excitation, pupil dilation, coma), vomiting, convulsions and/or tremors, and respiratory failure at high doses. (L1826)
Carcinogen Classification	Not listed by IARC.
운송 번호(UN)	2588
포장분류	II
위험 등급	6.1(a)

Avermectin B1b is the minor component (