(2R)-1-((9H-fluoren-9-ylmethoxy)carbonyl)pyrrolidine-2-carboxylic acid

FMOC-D-PRO-OH · FMOC-D-PRO · FMOC-D- · FMOC-D-PRO-OH H2O · n-[(9h-fluoren-9-ylmethoxy)carbonyl]-d-proline · (R)-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-(9H-FLUOREN-9-YLMETHYL) ESTER · Fmoc-D-proL · FMOC-D-PROLINE

https://huagongshe.com/ko/chemical/688136

(2R)-1-((9H-fluoren-9-ylmethoxy)carbonyl)pyrrolidine-2-carboxylic acid 분자 구조식

식별자 및 물리적 특성

CAS No.	101555-62-8
분자식	C20H19NO4
평균 분자량	337.4 g/mol
단동위원소 질량	337.13140809 g/mol
SMILES	O=C(O)[C@H]1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21
InChIKey	ZPGDWQNBZYOZTI-GOSISDBHSA-N
PubChem CID	688136
EC No.	691-539-6
DTXSID	DTXSID20906313

화학 및 물리적 성질

XLogP	3.4
극성 표면적	66.8
수소 결합 공여자 수	1
수소 결합 수용자 수	4
회전 가능 결합 수	4
무거운 원자 수	25
형식 전하	0
복잡도	500
녹는점	110-116°C
끓는 점	548.6±43.0 °C(Predicted)
밀도	1.328±0.06 g/cm3(Predicted)
굴절률	32 ° (C=1, DMF)
저장 조건	2-8°C
용해도	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pKa(산도 계수)	3.95±0.20(Predicted)
물리적 상태	powder to crystal
색상	흰색에서 밝은 노란색
BRN	5856698
주요 응용	펩타이드 합성
InChI	InChI=1S/C20H19NO4/c22-19(23)18-10-5-11-21(18)20(24)25-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2,(H,22,23)/t18-/m1/s1
InChIKey	ZPGDWQNBZYOZTI-GOSISDBHSA-N
SMILES	N1(C(OCC2C3=C(C=CC=C3)C3=C2C=CC=C3)=O)CCC[C@@H]1C(O)=O

화학적 성질

White powder

안전 및 규제

GHS 분류	WarningH302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard Classes and Categories	Skin Irrit. 2 (50%)
수질 위해 등급(WGK)	3
관세 코드	2933 99 80
안전 문구(S)	22-24/25
저장 분류	11 - Combustible Solids

용도

In organic synthesis, N-Fmoc-D-proline are often employed as important intermediates in various areas such as peptide synthesis, asymmetric synthesis, medicinal chemistry, and polymer chemistry.