덱스니굴디핀

(+)-Niguldipine

HCID 6918097CAS 120054-86-6
부분 구조 검색유사 구조 찾기

기본 정보

표준 SMILES
COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)[C@@H]1c1cccc([N+](=O)[O-])c1
InChIKey
SVJMLYUFVDMUHP-MGBGTMOVSA-N
분자식
C36H39N3O6
평균 분자량
609.7 g/mol
단동위원소 질량
609.28388597

개요

(4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O5-[3-(4,4-diphenyl-1-piperidinyl)propyl] ester O3-methyl ester is a diarylmethane.

이름 및 식별자

우선 이름
(+)-Niguldipine
IUPAC
5-O-[3-(4,4-diphenylpiperidin-1-yl)propyl] 3-O-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
현지명
덱스니굴디핀
영어명
Dexniguldipine
분자식
C36H39N3O6
분자량
609.71

이름 및 동의어

Dexniguldipine(R)-niguldipine120054-86-6(+)-NIGULDIPINEDexniguldipinoN9DG6ZTC43DTXSID70152666dexniguldipinumDexniguldipine.HClO3-(3-(4,4-di(phenyl)piperidin-1-yl)propyl) O5-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylateO3-[3-[4,4-di(phenyl)piperidin-1-yl]propyl] O5-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylateRefChem:905476
이름 더 보기
덱스니굴디핀(R)-Dexniguldipine(4R)-2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylic acid 3-methyl 5-[3-(4,4-diphenylpiperidino)propyl] ester(R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[3-(4,4-diphenylpiperidin-1-yl)propyl]-5-methyl ester3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[3-(4,4-diphenyl-1-piperidinyl)propyl] 5-methyl ester, (4R)-
DTXCID90820572B859 35((-)-3-Methyl-5-3-(4,4-diphenyl-l-piperidinyl)-propyl-l,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylate-hydrochloride)1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid, 3-(4,4-Diphenyl-1-piperidinyl)propyl Methyl Ester, Monohydrochloride (R)-3-(3-(4,4-diphenylpiperidin-1-yl)propyl) 5-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate(R)-Nigaldipine HydrochlorideDexniguldipine [INN]5-O-[3-(4,4-diphenylpiperidin-1-yl)propyl] 3-O-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

데이터베이스 식별자

CAS
120054-86-6
PubChem CID
6918097
DTXSID
DTXSID70152666
ChEMBL
CHEMBL2051956
ChEBI
CHEBI:103932
UNII
N9DG6ZTC43
Nikkaji
J401.544D

물성

구조 계산 물성

XLogP
6.8
극성 표면적
114 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
8
회전 가능 결합 수
11
무거운 원자 수
45

실험 및 물리화학적 성질

DrugsPharmaceuticals -> Listed in ZINC15

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 3건

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.

Substances that inhibit or prevent the proliferation of NEOPLASMS.

A class of drugs that act by selective inhibition of calcium influx through cellular membranes.

공급사2 곳

BOC Sciences16314854226; +8616314854226 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]

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