데이터를 보충하는 중입니다. 잠시 후 페이지를 새로 고치면 최신 내용을 볼 수 있습니다
기본 정보
- CAS
145603-76-5- 표준 SMILES
C=C1CC[C@H]2[C@](C)(CCC=C(C)C)[C@@H](OC(C)=O)CC[C@]2(C)[C@@H]1Cc1c(OC)oc(C)c(C)c1=O- InChIKey
RVADBFKZGNOVDI-PELMAWFUSA-N- 분자식
- C30H44O5
- 평균 분자량
- 484.677 g/mol
- 단동위원소 질량
- 484.31887451
이름 및 식별자
- 우선 이름
- 3-[[(1R,4aR,5S,6S,8aR)-6-(Acetyloxy)decahydro-5,8a-dimethyl-2-methylene-5-(4-methyl-3-penten-1-yl)-1-naphthalenyl]methyl]-2-methoxy-5,6-dimethyl-4H-pyran-4-one
- 영어명
- nalanthalide
- 분자식
- C30H44O5
- 분자량
- 484.67
이름 및 동의어
nalanthalide3-[[(1R,4aR,5S,6S,8aR)-6-(acetyloxy)decahydro-5,8a-dimethyl-2-methylene-5-(4-methyl-3-penten-1-yl)-1-naphthalenyl]methyl]-2-methoxy-5,6-dimethyl-4H-pyran-4-one4H-Pyran-4-one, 3-[[(1R,4aR,5S,6S,8aR)-6-(acetyloxy)decahydro-5,8a-dimethyl-2-methylene-5-(4-methyl-3-penten-1-yl)-1-naphthalenyl]methyl]-2-methoxy-5,6-dimethyl-
데이터베이스 식별자
- CAS
145603-76-5- PubChem CID
- 6918568
- DTXSID
DTXSID801099690- ChEMBL
CHEMBL516932- ChEBI
CHEBI:66610- Nikkaji
- J1.478.614G
물성
물리화학적 성질
- 녹는점
- 144 · 144-146 °C
- 끓는 점
- 573.5 · 573.5±50.0 °C(Predicted)
- 밀도
- 1.07 · 1.07±0.1 g/cm3(Predicted)
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
- 물리적 상태
- 고체
화학 및 산업
응용 분야
개요Nalanthalide is a diterpenoid pyrone fungal metabolite that has been found in Nalanthamala and has potassium channel inhibitory and antiviral activities. It inhibits binding of the potassium channel inhibitor charybdotoxin to Jurkat cell membranes (IC50 = 3 μM) and inhibits rubidium efflux from CHO cells expressing the voltage-gated potassium (Kv) channel Kv1.3 (IC50 = 3.9 μM). Nalanthalide depolarizes T cells in vitro with an EC50 value of 500 nM. It also inhibits HIV-1 integrase activity with IC50 values of 10 and 25 μM in coupled and strand transfer assays, respectively.
공급사3 곳
ChemeGen 中国18818260767 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
관련 반응
0건
현재 필터 조건에 해당하는 반응 기록이 없습니다.
화합물 노트
불러오는 중…