3-아미노-5-클로로-2-하이드록시벤젠설포닉산

3-Amino-5-chloro-2-hydroxybenzenesulfonic acid

HCID 6927

기본 정보

CAS
88-23-3
표준 SMILES
Nc1cc(Cl)cc(S(=O)(=O)O)c1O
InChIKey
YCTAOQGPWNTYJE-UHFFFAOYSA-N
분자식
C6H6ClNO4S
평균 분자량
223.63 g/mol
단동위원소 질량
222.97060635

개요

6-amino-4-chloro-1-phenol-2-sulfonic acid is an off-white solid. (NTP, 1992)

이름 및 식별자

우선 이름
3-Amino-5-chloro-2-hydroxybenzenesulfonic acid
IUPAC
3-amino-5-chloro-2-hydroxybenzenesulfonic acid
현지명
3-아미노-5-클로로-2-하이드록시벤젠설포닉산
영어명
2-Amino-4-chlorophenol-6-sulfonic acid
분자식
C6H6ClNO4S
분자량
223.63

이름 및 동의어

3-Amino-5-chloro-2-hydroxybenzenesulfonic acid88-23-32-Amino-4-chlorophenol-6-sulfonic Acid6-Amino-4-chloro-1-phenol-2-sulfonic acid4-Chloro-2-aminophenol-6-sulfonic acidBenzenesulfonic acid, 3-amino-5-chloro-2-hydroxy-CCRIS 4580DTXSID00244742-Hydroxy-5-chlorometanilic acidNSC 7539EINECS 201-813-583IP35P6EZ
이름 더 보기
3-아미노-5-클로로-2-하이드록시벤젠설포닉산4-Chloro-2-amino-6-sulfonicacid5-Chloro-2-hydroxymetanilic acid2-Amino-4-chlorphenol-6-sulfonsureMetanilic acid, 5-chloro-2-hydroxy-2-Amino-4-chlorophenol-6-sulfonicAci2-Amino-4-chlorophenyl-6-sulfonic acid6-Amino-4-chlorophenol-2-sulfonic acid
NSC-7539UNII-83IP35P6EZDTXCID904474EC 201-813-51-PHENOL-2-SULFONIC ACID, 6-AMINO-4-CHLORO-AMINO-4-CHLORO-1-PHENOL-2-SULFONIC ACID, 6-RefChem:92925201-813-5

데이터베이스 식별자

CAS
88-23-3
PubChem CID
6927
DTXSID
DTXSID0024474
ChEMBL
CHEMBL3184757
UNII
83IP35P6EZ
EC Number
201-813-5
Nikkaji
J28.729F

물성

구조 계산 물성

XLogP
0.8
극성 표면적
109 Ų
수소 결합 공여자 수
3
수소 결합 수용자 수
5
회전 가능 결합 수
1
무거운 원자 수
13

실험 및 물리화학적 성질

Solubilityless than 1 mg/mL at 70 °F (NTP, 1992)
Physical Description6-amino-4-chloro-1-phenol-2-sulfonic acid is an off-white solid. (NTP, 1992)

물리화학적 성질

밀도
1.79 · 1.790±0.06 g/cm3(Predicted)
저장 조건
Keep in dark place,Inert atmosphere,Room temperature
물리적 상태
powder to crystal
산도 계수 (pKa)
-1.53 · -1.53±0.50(Predicted)
색상
흰색에서 거의 흰색
EPA
2 · 2-Hydroxy-5-chlorometanilic acid (88-23-3)

안전 및 규제

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 3.6% (4 of 111) of reports.

Warning

H315 (96.4%): Causes skin irritation [Warning Skin corrosion/irritation]

P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)

Aggregated GHS information provided per 111 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory InformationStatus: Active Update: 24-09-2012 https://echa.europa.eu/registration-dossier/-/registered-dossier/10562
Fire HazardsFlash point data are not available for this compound, but it is probably combustible. (NTP, 1992)
Health HazardsSYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes and mucous membranes.
Reactive GroupPhenols and Cresols
Reactivity Profile6-AMINO-4-CHLORO-1-PHENOL-2-SULFONIC ACID may react with strong oxidizing or reducing agents and with mineral acids and bases (NTP, 1992)
Air and Water ReactionsMay be sensitive to prolonged exposure to air and/or light. Insoluble in water.

안전 및 보호

Fire FightingFires involving this compound should be controlled using a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1건

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

안전 데이터

tsca
TSCA listed
ridadr
2811
HS 번호
2922.29.8190
risk_code
34
hazard_code
C
safety_code
22-24/25-26-39

화학 및 산업

용도 및 제조

General Manufacturing InformationBenzenesulfonic acid, 3-amino-5-chloro-2-hydroxy-: ACTIVE

응용 분야

일반 설명Off-white solid.

제조 방법 · 1건

생산 방법2-Amino-4-chlorophenol-6-sulfonic acid obtained from p-chlorophenol by sulfonation and nitration is reduced with iron and hydrochloric acid without being precipitated. After filtering from the iron sludge, the highly alkaline reduction liquor is concentrated by evaporation and decolorized with activated carbon. Upon acidification 3-amino-5-chloro-2-hydroxybenzenesulfonic acid precipitates. Yield 72 %, based on p-chlorophenol.

공급사80 곳

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
宁波君龙新材料有限公司0574 88552216 19032109277 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]

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