3,5-Dibromopyridine (HCID 69369)

이름 및 식별자

우선 이름: 3,5-Dibromopyridine
IUPAC: 3,5-dibromopyridine
영어명: 3,5-Dibromopyridine
분자식: C5H3Br2N
분자량: 236.89

이름 및 동의어

3,5-Dibromopyridine625-92-3CHEBI:51593DTXSID3073921RefChem:486667DTXCID2043377210-916-4Pyridine, 3,5-dibromo-MFCD000146343,5-dibromo-pyridine3,5-dibromopyridin3,5-dibromo pyridine

이름 더 보기

NSC 62093,5-DibrompyridinIFLAB-BB F1995-01903,5-dibormopyridineTIMTEC-BB SBB0032373,5-Dibromopyridine>Perampanel Impurity 123,5-Dibromopyridine,99%

3.5-Dibromopyridine3,5-dibromo-pyridinHY-Y0491CS-W019948PS-4092AC-907/30002039F1995-0190Z57070461

데이터베이스 식별자

CAS: 625-92-3
PubChem CID: 69369
DTXSID: DTXSID3073921
ChEBI: CHEBI:51593
EC Number: 210-916-4
Nikkaji: J79.765K

물성

구조 계산 물성

XLogP: 2.2
극성 표면적: 12.9 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 1
회전 가능 결합 수: 0
무거운 원자 수: 8
형식 전하: 0
복잡도: 68

물리화학적 성질

녹는점: 110 · 110-115 °C (lit.)
끓는 점: 222 °C · 222 °C
밀도: 2.0383 · 2.0383 (rough estimate)
굴절률: 1.58 · 1.5800 (estimate)
저장 조건: Inert atmosphere,Room Temperature
용해도: DMSO(약간 용해됨, 가열), 메탄올(약간 용해됨)
산도 계수 (pKa): 0.52 · 0.52±0.20(Predicted)
물리적 상태: 바늘 같은 수정
색상: 흰색~밝은 베이지
수용성: 클로로포름과 메탄올에 용해됩니다. 물에 불용성.
BRN: 108477 · 108477
InChI: 1S/C5H3Br2N/c6-4-1-5(7)3-8-2-4/h1-3H
InChIKey: SOSPMXMEOFGPIM-UHFFFAOYSA-N
SMILES: Brc1cncc(Br)c1
NIST: 3 · 3,5-Dibromopyridine(625-92-3)
EPA: 3 · 3,5-Dibromopyridine (625-92-3)

화학적 성질

Light-Yellow Solid

안전 및 규제

GHS 분류

GHS Classification · 5건

Warning

H302 (18.9%): Harmful if swallowed [Warning Acute toxicity, oral]；H312 (15.1%): Harmful in contact with skin [Warning Acute toxicity, dermal]；H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H332 (15.1%): Harmful if inhaled [Warning Acute toxicity, inhalation]；H335 (96.2%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 53 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information3,5-Dibromopyridine: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesAcute Tox. 4 (18.9%)；Acute Tox. 4 (15.1%)；Skin Irrit. 2 (100%)；Eye Irrit. 2 (100%)；Acute Tox. 4 (15.1%)；STOT SE 3 (96.2%)

규제 정보

Regulatory Information3,5-Dibromopyridine: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk: 3
ridadr: UN2811
HS 번호: 29333999
risk_code: 36/37/38-20/21/22
hazard_code: Xi,Xn
safety_code: 26-36-36/37/39
위험 등급: IRRITANT
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

응용 분야 · 2건

용도3-Acetylamino-5-ethoxypyridine was prepared by converting 3, 5-dibromopyridine with sodium ethylate into 3-bromo-5-ethoxypyridine, allowing this substance to interact with ammonia and acetylating the aminoethoxypyridine thus formed with acetic anhydride. Lithiation of 3, 5-dibromopyridine with LDA and subsequent reaction with electrophiles provided 4-alkyl-3, 5-dibromopyridines 2 in high yield. Ligand was prepared by a Pd(0)-catalyzed cross-coupling reaction of 3,5-dibromopyridine and 5-tributylstannyl-3,3-bipyridine. The synthesis of 3, 5-bis (2-indolyl) pyridine and 3-[(2-indolyl)-5-phenyl] pyridine derivatives as includes Stille or Suzuki type reactions, which were realized on the 3,5-dibromopyridine.

일반 설명3,5-Dibromopyridine undergoes lithiation with lithium diisopropylamide and on subsequent reaction with electrophiles yields 4-alkyl-3,5-dibromopyridines.

상·하류 제품 정보

하류 제품

5-Bromo-2-fluoro-3-methoxypyridine 5-(벤질록시)피리딘-3-아민 3-Amino-5-hydroxypyridine 5-메톡시피리딘-3-아민 3-(BENZYLOXY)-5-BROMOPYRIDINE 5-Bromopyridine-3-boronic acid 3-Amino-5-bromopyridine 3-Bromo-5-fluoropyridine 5-METHOXY-PYRIDINE-3-CARBALDEHYDE 3-BROMO-5-(METHYLTHIO)PYRIDINE 2-(5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)propan-2-ol 4,6-Di(4-carboxyphenyl)pyrimidine

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

北京华美互利生物化工010-56205725 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

山东艾利特生物科技有限公司0539-18853986-090 13053958157 · [email protected]

연결된 노트

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3,5-Dibromopyridine

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