1,2,3,4-Tetrahydroquinoline (HCID 69460)

개요

1,2,3,4-tetrahydroquinoline is a member of the class of quinolines that is the 1,2,3,4-tetrahydro derivative of quinoline.

이름 및 식별자

우선 이름: 1,2,3,4-Tetrahydroquinoline
IUPAC: 1,2,3,4-tetrahydroquinoline
영어명: 1,2,3,4-Tetrahydroquinoline
분자식: C9H11N
분자량: 133.19

이름 및 동의어

1,2,3,4-Tetrahydroquinoline635-46-1KusolQuinoline, 1,2,3,4-tetrahydro-CCR50N1Z9GNSC-15311DTXSID8060903CHEBI:213323RefChem:71328DTXCID3043940211-237-61,2,3,4-Hydroquinoline

이름 더 보기

Tetrahydroquinoline200g200G/1KG/5KG1-AZATETRALINAURORA KA-684AKOS BBS-000035961,2,3,4-TetrahydroquPy-Tetrahydroquinoline

1,2,3,4-Tetrahydro-quinolineMFCD000066931,2,3,4-tetrahydro quinolineUNII-CCR50N1Z9G1,2,3,4-Tetrahydrochinoline1,3,4-Tetrahydroquinoline3,4-dihydro-2H-quinolineAKOS000119058

데이터베이스 식별자

CAS: 635-46-1
PubChem CID: 69460
DTXSID: DTXSID8060903
ChEMBL: CHEMBL303611
ChEBI: CHEBI:213323
UNII: CCR50N1Z9G
EC Number: 211-237-6
Nikkaji: J6.910H

물성

구조 계산 물성

XLogP: 2.3
극성 표면적: 12 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 1
회전 가능 결합 수: 0
무거운 원자 수: 10
형식 전하: 0
복잡도: 111

실험 및 물리화학적 성질

Chemical ClassesNitrogen Compounds -> Quinolines

SpringerMaterials PropertiesChemical shift

Vapor Pressure0.04 [mmHg]

Physical DescriptionYellow liquid; [MSDSonline]

물리화학적 성질

녹는점: 9 · 9-14 °C (lit.)
끓는 점: 113 · 113-117 °C/10 mmHg (lit.) 249 °C (lit.)
밀도: 1.061 g/mL · 1.061 g/mL at 25 °C (lit.)
굴절률: 20 · n20/D 1.593(lit.)
인화점: 213 °F · 213 °F
저장 조건: Keep in dark place,Sealed in dry,Room Temperature
물리적 상태: 액체
산도 계수 (pKa): 5.09 · 5.09±0.20(Predicted)
색상: 맑은 연한 노란색에서 노란색까지
수소이온지수(pH): 10 · 10-11 (111g/l, H2O, 20℃)(as an emulsion)
냄새: 1 % · 디프로필렌 글리콜 중 1.00%. 꿀 사향고양이 동물 페놀릭
냄새 유형: 동물
생물학적 소스: synthetic
수용성: 1 g/L · <1g/L(20℃)
BRN: 116149 · 116149
InChI: 1S/C9H11N/c1-2-6-9-8(4-1)5-3-7-10-9/h1-2,4,6,10H,3,5,7H2
InChIKey: LBUJPTNKIBCYBY-UHFFFAOYSA-N
SMILES: C1CNc2ccccc2C1
LogP: 2.29 · 2.290
NIST: 1 · Quinoline, 1,2,3,4-tetrahydro-(635-46-1)
EPA: 1 · 1,2,3,4-Tetrahydroquinoline (635-46-1)

화학적 성질

Clear pale yellow to yellow liquid. It is easily oxidized in air and may acquire a pale amber colour if exposed to air and daylight. Solidifies in the cold.

안전 및 규제

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 13.4% (11 of 82) of reports.

Warning

H315 (76.8%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 82 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 3건

Chemical: Quinoline, 1,2,3,4-tetrahydro-

Status: Active Update: 19-12-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/27183

Quinoline, 1,2,3,4-tetrahydro-: Does not have an individual approval but may be used under an appropriate group standard

Hazards Summary · 1건

A skin and respiratory tract irritant; May be absorbed through the skin; [MSDSonline] May be toxic to the CNS, cornea, retina, and optic nerve; May be absorbed by skin contact; Quinoline causes liver injury and liver cancer in animal experiments; See Quinoline.

Hazard Classes and CategoriesSkin Irrit. 2 (76.8%)

독성 정보

Adverse EffectsNeurotoxin - Other CNS neurotoxin

안전 데이터

wgk: 3
tsca: TSCA listed
HS 번호: 29334990
risk_code: 36/37/38-45
hazard_code: Xi,T
safety_code: 26-36/37-36-45-53
기존화학 물질: KE-33506
Hazard Classifications: Acute Tox. 3 OralAquatic Chronic 3
스토리지 클래스: 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects

화학 및 산업

용도 및 제조

General Manufacturing InformationQuinoline, 1,2,3,4-tetrahydro-: ACTIVE

응용 분야

용도1,2,3,4-Tetrahydroquinoline is a reagent used in the synthesis of N-substituted benzoyl-1,2,3,4-tetrahydroquinolyl-1-carboxamides displaying fungicidal activity.

상·하류 제품 정보

상류 원료

퀴놀린 모노에틸렌글리콜

하류 제품

6-Bromoquinoline 7-아미노-1-메틸-1,2,3,4-테트라히드로퀴놀린 1,2,3,4-Tetrahydro-8-hydroxyquinoline 릴로리딘 7-니트로-퀴놀린 4-티아졸 카르복실산 1-Piperidinecarboxylic acid, 4-(3,4-dihydro-1(2H)-quinolinyl)-, 1,1-dimethylethyl ester Quinoline, 8-ethyl-1,2,3,4-tetrahydro-6-요오도-1,2,3,4-테트라하이드로퀴놀린 7-HYDROXY-5-OXO-N-PROPYL-2,3-DIHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE-6-CARBOXAMIDE

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

INTATRADE GmbH+49 3493/605464 · [email protected]

T&W GROUP021-61551611 13296011611 · [email protected]

추가 설명

정의ChEBI: A member of the class of quinolines that is the 1,2,3,4-tetrahydro derivative of quinoline.

연결된 노트

불러오는 중…

1,2,3,4-Tetrahydroquinoline

기본 정보

개요