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기본 정보
- CAS
784138-08-5- 표준 SMILES
COc1cccc2c(C(=O)N3CCN(C)C(C)C3)cn(CC3CCCCC3)c12- InChIKey
ONXJNAIZJKLJGA-UHFFFAOYSA-N- 분자식
- C23H33N3O2
- 평균 분자량
- 383.536 g/mol
- 단동위원소 질량
- 383.2572773
이름 및 식별자
- 우선 이름
- [1-(Cyclohexylmethyl)-7-methoxy-1H-indol-3-yl](3,4-dimethyl-1-piperazinyl)-methanone
- 영어명
- (±)-ORG 28611
- 분자식
- C23H33N3O2
- 분자량
- 383.527
이름 및 동의어
(±)-ORG 28611[1-(cyclohexylmethyl)-7-methoxyindol-3-yl]-(3,4-dimethylpiperazin-1-yl)methanone
데이터베이스 식별자
- CAS
784138-08-5- PubChem CID
- 69488934
- DTXSID
DTXSID401024627
물성
물리화학적 성질
- 용해도
- 10 mg/ml; · DMF: 10 mg/ml; DMSO: 2 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
- 물리적 상태
- 결정성 고체
화학 및 산업
응용 분야
개요(±)-ORG 28611 is the racemic mixture of the water soluble, full agonist of the human cannabinoid (CB) receptors central CB1 (pEC50 = 7.6; pKi = 8.9) and peripheral CB2 (pKi = 8.8). ORG 28611 (0.1-1 μM/kg, intravenous) demonstrated antinociceptive activity in the mouse tail flick test and the mouse formalin paw test, and it was further evaluated clinically for use as a potential intravenous analgesic agent.
용도(±)-ORG 28611 is full agonist of the human cannabinoid (CB) receptors central CB1 (pEC50 = 7.6; pKi = 8.9) and peripheral CB2 (pKi = 8.8). ORG 28611 (0.1-1 μM/kg, intravenous) demonstrated antinociceptive activity in the mouse tail flick test and the mouse formalin paw test, and it was further evaluated clinically for use as a potential intravenous analgesic agent. Synthetic Cannabinoids
공급사3 곳
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
上海宏叶生物科技有限公司400-9205774 400-920-5774 · [email protected]
ChemeGen 中国18818260767 · [email protected]
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