2-Chloro-N-(2,6-dimethylphenyl)acetamide

Lidocaine EP Impurity H · 2-CHLORO-2',6'-ACETOXYLIDIDE · N-CHLOROACETYL-2,6-DIMETHYLANILINE · NSC 37260 · 2-Chloro-N-(2 · acetoxylidide · AKOS BBS-00000875 · LIDOCAINE EP IMP H

https://huagongshe.com/ko/chemical/70798

2-Chloro-N-(2,6-dimethylphenyl)acetamide 분자 구조식

식별자 및 물리적 특성

CAS No.	1131-01-7
분자식	C10H12ClNO
평균 분자량	197.66 g/mol
단동위원소 질량	197.0607417 g/mol
SMILES	Cc1cccc(C)c1NC(=O)CCl
InChIKey	FPQQSNUTBWFFLB-UHFFFAOYSA-N
PubChem CID	70798
EC No.	214-460-7
DTXSID	DTXSID4061545

화학 및 물리적 성질

XLogP	1.9
극성 표면적	29.1
수소 결합 공여자 수	1
수소 결합 수용자 수	1
회전 가능 결합 수	2
무거운 원자 수	13
형식 전하	0
복잡도	174
Physical Description	White or grey powder[Alfa Aesar MSDS]
녹는점	150-151 °C(lit.)
끓는 점	316.8±30.0 °C(Predicted)
밀도	1.1363 (rough estimate)
굴절률	1.5330 (estimate)
저장 조건	2-8°C
용해도	클로로포름(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨)
pKa(산도 계수)	12.91±0.70(Predicted)
물리적 상태	결정질 분말 또는 바늘
색상	흰색에서 갈색으로
용해도	클로로포름, 메탄올에 용해됩니다. 물에 불용성.
BRN	781309
안정성	감광성
InChI	1S/C10H12ClNO/c1-7-4-3-5-8(2)10(7)12-9(13)6-11/h3-5H,6H2,1-2H3,(H,12,13)
InChIKey	FPQQSNUTBWFFLB-UHFFFAOYSA-N
SMILES	Cc1cccc(C)c1NC(=O)CCl
NIST	2-Chloro-2',6'-acetoxylidide(1131-01-7)
EPA	Acetamide, 2-chloro-N-(2,6-dimethylphenyl)- (1131-01-7)

화학적 성질

beige needles or crystalline powder

안전 및 규제

GHS 분류	WarningH302 (70.3%): Harmful if swallowed [Warning Acute toxicity, oral]H315 (29.7%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (99.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (29.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 165 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
규제 정보	Status: Active Update: 29-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/18637
유해성 요약	A skin and strong eye irritant[Alfa Aesar MSDS] See Acetanilide.
Hazard Classes and Categories	Acute Tox. 4 (70.3%)Skin Irrit. 2 (29.7%)Eye Irrit. 2 (99.4%)STOT SE 3 (29.1%)
수질 위해 등급(WGK)	3
TSCA 등재 상태	TSCA listed
관세 코드	29214200
위험 문구(R)	36/37/38
위험 표시	Xi
안전 문구(S)	26-37/39
위험 등급	IRRITANTEye Irrit. 2Skin Irrit. 2STOT SE 3
저장 분류	11 - Combustible Solids

용도

Lidocaine intermediate.

일반 설명

N-(2,6-Dimethylphenyl)chloroacetamide (2-chloro-2′,6′-acetoxylidide) is nonsteroidal antinflammatory drug.