기본 정보
- CAS
92-32-0- 표준 SMILES
CN(C)c1ccc2cc3ccc(=[N+](C)C)cc-3oc2c1.[Cl-]- InChIKey
INCIMLINXXICKS-UHFFFAOYSA-M- 분자식
- C17H19N2O.Cl
- 평균 분자량
- 302.8 g/mol
- 단동위원소 질량
- 302.1185909
개요
Pyronin Y is an organic chloride salt having 6-(dimethylamino)-N,N-dimethyl-3H-xanthen-3-iminium as the cation. Used with methyl green to selectively demonstrate RNA (red) in contrast to DNA (green) with the Unna-Pappenheim method. It has a role as a histological dye. It is an iminium salt and an organic chloride salt. It contains a pyronin Y cation.
이름 및 식별자
- 우선 이름
- Pyronine
- IUPAC
- [6-(dimethylamino)xanthen-3-ylidene]-dimethylazanium chloride
- 현지명
- 피로닌 Y
- 영어명
- PYRONIN Y
- 분자식
- C17H19ClN2O
- 분자량
- 302.8
이름 및 동의어
Pyronin Y92-32-0Pyronine YPyroninePyronin GPyronin YellowPyronine GTetramethyl pyronin3,6-Bis(dimethylamino)xanthylium chlorideMethyl pyroninXanthylium, 3,6-bis(dimethylamino)-, chloridePyronine ZH
이름 더 보기
피로닌Y피로닌YPyonin GPyonin YCI 45005PYRONIN J
C.I. 45005tetramethyldiaminoxanthylium chlorideSchultz No. 853NSC-10454W659G165T1CHEBI:8682DTXSID8059051CI-45005
데이터베이스 식별자
- CAS
92-32-0- PubChem CID
- 7085
- DTXSID
DTXSID8059051- ChEMBL
CHEMBL1486690- ChEBI
CHEBI:8682- UNII
- W659G165T1
- EC Number
- 202-147-8
물성
구조 계산 물성
- 극성 표면적
- 15.5 Ų
- 수소 결합 공여자 수
- 0
- 수소 결합 수용자 수
- 3
- 회전 가능 결합 수
- 1
- 무거운 원자 수
- 21
- 형식 전하
- 0
- 복잡도
- 480
실험 및 물리화학적 성질
Chemical ClassesDyes -> Acridine Dyes
Physical Description
Liquid
Lustrous green solid; [Merck Index] Iridescent green crystals; [Amresco MSDS]
물리화학적 성질
- 녹는점
- 250 · 250-260 °C(lit.)
- 저장 조건
- room temp
- 용해도
- 물에 용해됨; 에탄올, 에틸렌 글리콜, 메틸 셀로솔브에 난용성
- 물리적 상태
- 분말/고체
- 색상
- 분홍색
- 수용성
- 물에 용해됩니다. 또한 메틸 셀로솔브(9mg/mL) 및 에탄올(3mg/mL)에도 용해됩니다.
- Merck
- 13 · 13,8097
- BRN
- 3795789 · 3795789
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다.
- 주요 응용
- 진단 검사 제조혈액학조직학
- InChI
- 1S/C17H19N2O.ClH/c1-18(2)14-7-5-12-9-13-6-8-15(19(3)4)11-17(13)20-16(12)10-14;/h5-11H,1-4H3;1H/q+1;/p-1
- InChIKey
- INCIMLINXXICKS-UHFFFAOYSA-M
- SMILES
- [Cl-].CN(C)c1ccc2C=C3C=C\C(C=C3Oc2c1)=[N+](/C)C
- EPA
- Pyronine Y (92-32-0)
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Warning
H341 (100%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
유해성 정보
Regulatory Information
Chemical: Methanaminium, N-[6-(dimethylamino)-3H-xanthen-3-ylidene]-N-methyl-, chloride
Xanthylium, 3,6-bis(dimethylamino)-, chloride (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Xanthylium, 3,6-bis(dimethylamino)-, chloride (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Xanthylium, 3,6-bis(dimethylamino)-, chloride: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryCauses changes in kidneys (acute tubular necrosis) in intravenous lethal-dose studies of mice (LD50 = 179 mg/kg); [RTECS] A skin and strong eye irritant; Targets the kidney and bladder; [Amresco MSDS]
Hazard Classes and CategoriesMuta. 2 (100%)
안전 데이터
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- BQ1450000
- HS 번호
- 32041300
- risk_code
- 68-36/37/38
- hazard_code
- Xn,Xi
- safety_code
- 22-24/25-36-26
- 기존화학 물질
- KE-03052
화학 및 산업
약리 정보
MeSH Pharmacological ClassificationChemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.
용도 및 제조
UsesUsed as a bacterial and biological stain; [Merck Index]
U.S. Production2022: 11,116 lb
Industry UsesFiller
General Manufacturing Information
All Other Chemical Product and Preparation Manufacturing
Xanthylium, 3,6-bis(dimethylamino)-, chloride (1:1): ACTIVE
응용 분야
용도Pyronin Y is a cationic dye that intercalates RNA and is visible as a red band during electrophoresis. It has also been shown to accumulate in mitochondria of viable cells. In conjuction with Methyl Green or Nancy-520, Pyronin Y can be used as a fluorescent differential stain of nucleic acids in paraffin tissue sections.
일반 설명Pyronin Y (C.I. 45005) is an aminoxanthene dye that is present as a weakly lipophilic cation in neutral aqueous solutions. It is also known as pyronine G.
공급사100 곳
国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
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