Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-페닐피페라진이염산염
1-페닐피페라진이염산염 · Nsc150847 · 1-Phenylpiperazine2HCl · 1-Phenylpiperazine hHdrochloride · Phenylpiperazine (hydrochloride) · 1-Phenylpiperazine dihydrochloride · N-Phenylpiperazine Dihydrochloride · 4-Phenylpiperazine Dihydrochloride
식별자 및 물리적 특성
| CAS No. | 4004-95-9 |
|---|---|
| 분자식 | C10H14N2 |
| 평균 분자량 | 162.23 g/mol |
| 단동위원소 질량 | 162.11569846 g/mol |
| SMILES | c1ccc(N2CCNCC2)cc1 |
| InChIKey | YZTJYBJCZXZGCT-UHFFFAOYSA-N |
| PubChem CID | 7096 |
| ChEMBL | CHEMBL9434 |
| EC No. | 202-165-6 |
| DTXSID | DTXSID8057855 |
| 현지명 | 1-페닐피페라진이염산염 |
화학 및 물리적 성질
| XLogP | 1.1 |
|---|---|
| 극성 표면적 | 15.3 |
| 수소 결합 공여자 수 | 1 |
| 수소 결합 수용자 수 | 2 |
| 회전 가능 결합 수 | 1 |
| 무거운 원자 수 | 12 |
| 형식 전하 | 0 |
| 복잡도 | 124 |
| Dissociation Constants | 9 |
| 녹는점 | 221-223°C |
| 저장 조건 | Hygroscopic, Refrigerator, Under Inert Atmosphere |
| 용해도 | DMSO(약간 용해됨), 메탄올(약간 용해됨), 물(약간 용해됨) |
| 물리적 상태 | 고체 |
| 색상 | 흰색에서 황백색까지 |
| 안정성 | 흡습성 |
화학적 성질
White Solid
안전 및 규제
| GHS 분류 | DangerH301 (96.9%): Toxic if swallowed [Danger Acute toxicity, oral]H310 (36.9%): Fatal in contact with skin [Danger Acute toxicity, dermal]H311 (61.5%): Toxic in contact with skin [Danger Acute toxicity, dermal]H314 (98.5%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]P260, P262, P264, P270, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P361+P364, P363, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 65 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| 규제 정보 | Status: Active Update: 09-04-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/21606Piperazine, 1-phenyl-, dihydrochloride: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.Phenylpiperazine: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Acute Tox. 3 (96.9%)Acute Tox. 2 (36.9%)Acute Tox. 3 (61.5%)Skin Corr. 1B (98.5%) |
| 신호 어 | Warning |
| 유해·위험 문구 | 암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드 H315 |
용도
용도
1-Phenylpiperazine was tested for its activity as a topical glaucoma agent.