D-Tyrosine (HCID 71098)

이름 및 식별자

우선 이름: D-Tyrosine
IUPAC: (2R)-2-amino-3-(4-hydroxyphenyl)propanoic acid
영어명: D-Tyrosine
분자식: C9H11NO3
분자량: 181.19

이름 및 동의어

D-tyrosine556-02-5(2R)-2-amino-3-(4-hydroxyphenyl)propanoic acidD-TyrD-Tyrosin(R)-TYROSINEWQ5G9JQ7GCCHEBI:28479(R)-3-(p-Hydroxyphenyl)alanineEINECS 209-112-6D-4-HYDROXYPHENYLALANINEDTXSID50883441

이름 더 보기

D-Tyr-OHD-THREONINOLD(+)-TYROSINED-thyrosineTYROSINE, D-D-p-TyrosineD-Tyrosine98%

(R)-2-Amino-3-(p-hydroxyphenyl)propionic acid2-amino-3-(4-hydroxyphenyl)-propanoic acidRefChem:585118DTXCID601022972(2R)-2-azaniumyl-3-(4-hydroxyphenyl)propanoate209-112-6H-D-Tyr-OH(R)-2-amino-3-(4-hydroxyphenyl)propanoic acid

데이터베이스 식별자

CAS: 556-02-5
PubChem CID: 71098
DTXSID: DTXSID50883441
ChEMBL: CHEMBL1076637
ChEBI: CHEBI:28479
UNII: WQ5G9JQ7GC
EC Number: 209-112-6
Nikkaji: J9.196K

물성

구조 계산 물성

XLogP: -2.3
극성 표면적: 83.6 Å²
수소 결합 공여자 수: 3
수소 결합 수용자 수: 4
회전 가능 결합 수: 3
무거운 원자 수: 13
형식 전하: 0
복잡도: 176

실험 및 물리화학적 성질

Solubility453

물리화학적 성질

녹는점: 300 °C · >300 °C (lit.)
끓는 점: 314.29 °C · 314.29°C (rough estimate)
밀도: 1.2375 · 1.2375 (rough estimate)
굴절률: 11.2 ° · 11.2 ° (C=5, 1mol/L HCl)
저장 조건: Store at RT.
용해도: 산성수(약간 용해됨), 메탄올(약간 용해됨), 물(약간 용해됨)
산도 계수 (pKa): 2.25 · 2.25±0.10(Predicted)
물리적 상태: 결정 또는 분말
색상: 흰색에서 황백색까지
수용성: 녹는
Merck: 14 · 14,9839
BRN: 2212157 · 2212157
주요 응용: 펩타이드 합성
화장품 원료 기능: 향기헤어 컨디셔닝대전방지제피부 컨디셔닝
InChI: 1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m1/s1
InChIKey: OUYCCCASQSFEME-UHFFFAOYSA-N
SMILES: N[C@H](Cc1ccc(O)cc1)C(O)=O
LogP: -0.418 · -0.418 (est)
EPA: D-Tyrosine (556-02-5)

화학적 성질

white to off-white powder

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 82.4% (42 of 51) of all reports.

Warning

H315 (17.6%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (17.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (15.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 51 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 42 of 51 reports by companies.；There are 6 notifications provided by 9 of 51 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory InformationChemical: D-Tyrosine

Other Safety InformationIMAP assessments - D-Tyrosine: Environment tier I assessment；Evaluation - Chemicals that are unlikely to require further regulation to manage risks to human health

Hazard Classes and CategoriesSkin Irrit. 2 (17.6%)；Eye Irrit. 2 (17.6%)；STOT SE 3 (15.7%)

규제 정보

Regulatory InformationChemical: D-Tyrosine

안전 데이터

wgk: 3
tsca: TSCA listed
HS 번호: 29225000
risk_code: 36/37/38
hazard_code: Xi
safety_code: 26-36-24/25
스토리지 클래스: 13 - Non Combustible Solids

화학 및 산업

용도 및 제조

General Manufacturing InformationD-Tyrosine: INACTIVE

응용 분야 · 1건

용도D-Tyrosine, the stereoisomer to L-Tyrosine (T899975), is an amino acid used in various organic syntheses for antibiotics. It is used in the synthesis of (-)-anisomycin, as well as BATSI (boronic acid transition state inhibitors) which act on β-lactamases. It has also been studied as an inhibitor of microbial growth on surfaces, reducing microbial attachment to hydrophillic glass and hydrophobic po lypropylene surfaces.

상·하류 제품 정보

상류 원료

클로로아세틸 클로라이드 DL-Tyrosine

하류 제품

BOC-D-TYR(BZL)-OH H-3,5-DIBROMO-D-TYR-OH N,O-Di-BOC-D-tyrosine 3-Bromo-D-Tyrosine

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

北京华美互利生物化工010-56205725 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

INTATRADE GmbH+49 3493/605464 · [email protected]

추가 설명 · 1건

정의ChEBI: D-tyrosine is an optically active form of tyrosine having D-configuration. It has a role as an Escherichia coli metabolite. It is a tyrosine and a D-alpha-amino acid. It is a conjugate base of a D-tyrosinium. It is a conjugate acid of a D-tyrosinate(1-). It is an enantiomer of a L-tyrosine. It is a tautomer of a D-tyrosine zwitterion.