기본 정보
- CAS
7790-26-3- 표준 SMILES
[131I-].[Na+]- InChIKey
FVAUCKIRQBBSSJ-LAIFMVDKSA-M- 분자식
- INa
- 평균 분자량
- 153.8959 g/mol
- 단동위원소 질량
- 153.895896
개요
Sodium Iodide I-131 is a radiopharmaceutical containing the beta- and gamma-emitting radioisotope I-131. After absorption, the iodide is distributed through the extracellular fluid of the body and accumulates in the thyroid gland, thereby allowing the imaging of the thyroid.
이름 및 식별자
- 우선 이름
- Sodium Iodide I-131
- IUPAC
- sodium iodine-131(1-)
- 영어명
- sodium iodide
- 분자식
- INa
- 분자량
- 149.89
이름 및 동의어
Sodium iodide I 131Sodium iodide I-131OriodideRadiocapsSodium iodide-131TheriodideTracervialSodium Iodide, I-131Theriodide-131Tracervial-131Radiocaps-131Sodium iodide i131
이름 더 보기
Na(131)ISodium Iodide, RadioactiveSodium Iodide (131I) Capsules
HiconIodine (131i) sodium29VCO8ACHHSodium iodide (131 i)Iodotope I-131Sodium iodide,i-131(131-I)Sodium iodideIoduro sodico (131I)
데이터베이스 식별자
- CAS
7790-26-3- PubChem CID
- 71368
- DTXSID
DTXSID701014487- ChEMBL
CHEMBL1201084- UNII
- 29VCO8ACHH
- Nikkaji
- J1.576.106G
물성
구조 계산 물성
- 극성 표면적
- 0 Ų
- 수소 결합 공여자 수
- 0
- 수소 결합 수용자 수
- 1
- 회전 가능 결합 수
- 0
- 무거운 원자 수
- 2
- 형식 전하
- 0
- 복잡도
- 2
실험 및 물리화학적 성질
Human Drugs
Breast Feeding; Lactation; Milk, Human; Radiopharmaceuticals; Iodine Radioisotopes
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
물리화학적 성질
- EPA
- Sodium iodide (Na131I) (7790-26-3)
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
독성 정보
Adverse Effects
Although iodine channels express predominantly in thyroid cells, additional cell types express this receptor, including the lactating breast, gastric mucosa, and salivary and lacrimal glands, leading to dose-dependent short- and long-term side effects. Acute sialoadenitis, the most common short-term side effect from RAI (approximately 30% incidence), can occur as early as several hours after treatment and may persist for up to one year following therapy. Xerostomia (approximately 20 to 40% incidence), a complication associated with hyposalivation, manifests weeks to months following RAI and can persist for months to years. Repercussions of chronic hyposalivation include increased incidence of dental caries, dysgeusia (altered taste), and difficulty with mastication and deglutition. Other adverse effects of RAI therapy include nausea, alopecia, conjunctivitis, and xerophthalmia (dry eyes).
Effects During Pregnancy and Lactation◉ Summary of Use during Lactation
안전 데이터
- tsca
- TSCA listed
화학 및 산업
약리 정보
ATC Code
V - Various
V - Various
QV - Various
QV - Various
FDA Pharmacological Classification
SODIUM IODIDE I 131
Radiopharmaceutical Activity [MoA]; Radioactive Therapeutic Agent [EPC]
용도 및 제조
General Manufacturing InformationSodium iodide (Na131I): ACTIVE
응용 분야
용도Antineoplastic; diagnostic aid (thyroid function determination); radioactive agent.
공급사1 곳
Hubei Langyou International Trading Co., Ltd+86-12345678900 +86-18874586545 · [email protected]
관련 반응
0건
현재 필터 조건에 해당하는 반응 기록이 없습니다.
화합물 노트
불러오는 중…