(R)-(+)-알파-히드록시-감마-부티로락톤

2-Hydroxy-gamma-butyrolactone, (2R)-

HCID 7157070

노트 반응

부분 구조 검색 유사 구조 찾기

기본 정보

CAS: 56881-90-4
표준 SMILES: O=C1OCC[C@H]1O
InChIKey: FWIBCWKHNZBDLS-GSVOUGTGSA-N
분자식: C4H6O3
평균 분자량: 102.09 g/mol

이름 및 식별자

우선 이름: 2-Hydroxy-gamma-butyrolactone, (2R)-
IUPAC: (3R)-3-hydroxyoxolan-2-one
현지명: (R)-(+)-알파-히드록시-감마-부티로락톤
영어명: (R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
분자식: C4H6O3
분자량: 102.09

이름 및 동의어

56881-90-4(R)-3-Hydroxydihydrofuran-2(3H)-one(R)-(+)-alpha-Hydroxy-gamma-butyrolactone(3R)-3-hydroxyoxolan-2-one(R)-alpha-hydroxy-gamma-butyrolactoneSG03T0K3QH2(3H)-Furanone, dihydro-3-hydroxy-, (3R)-(3R)-Dihydro-3-hydroxy-2(3H)-furanone2-Hydroxy-gamma-butyrolactone, (+)-2-Hydroxy-gamma-butyrolactone, (2R)-2-HYDROXY-.GAMMA.-BUTYROLACTONE, (+)-2-HYDROXY-.GAMMA.-BUTYROLACTONE, (2R)-

이름 더 보기

(R)-(+)-알파-히드록시-감마-부티로락톤-Hydroxy-γRARECHEM AK HZ 0027(R)-2-HYDROXYBUTYROLACTONE3-deoxy-L-glycero-tetronolactone(R)-2-HYDROXY-GAMMA-BUTYROLACTONE(R)-(+)-α-Hydroxy-γ-butyrolactone(R)-(+)-α-Hydroxy-γ-butyrolactone(3R)-3-hydroxytetrahydrofuran-2-one(R)-(+)-α-Hydroxy-γ-butyrolactone>

(R)-.ALPHA.-HYDROXY-.GAMMA.-BUTYROLACTONE(R)-(+)-.ALPHA.-HYDROXY-.GAMMA.-BUTYROLACTONERefChem:473334894-399-6MFCD00211246(R)-(+)-|A-Hydroxy-|A-butyrolactoneUNII-SG03T0K3QH(3R)-3-hydroxydihydro-2(3H)-furanone

데이터베이스 식별자

CAS: 56881-90-4
PubChem CID: 7157070
UNII: SG03T0K3QH
EC Number: 894-399-6
Nikkaji: J517.045A

물성

구조 계산 물성

XLogP: -0.4
극성 표면적: 46.5 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 3
회전 가능 결합 수: 0
무거운 원자 수: 7
형식 전하: 0
복잡도: 88.9

물리화학적 성질

끓는 점: 133 °C/10 · 133 °C/10 mmHg (lit.)
밀도: 1.309 g/mL · 1.309 g/mL at 25 °C (lit.)
굴절률: 20 · n20/D 1.467(lit.)
인화점: 230 °F · >230 °F
저장 조건: 2 · 2-8°C
물리적 상태: 투명한 액체
산도 계수 (pKa): 13.07 · 13.07±0.20(Predicted)
Specific Gravity: 1.32 · 1.32
색상: 무색~연황색
BRN: 80588 · 80588
InChI: 1S/C4H6O3/c5-3-1-2-7-4(3)6/h3,5H,1-2H2/t3-/m1/s1
InChIKey: FWIBCWKHNZBDLS-GSVOUGTGSA-N
SMILES: O[C@@H]1CCOC1=O

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

유해성 정보

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

안전 데이터

wgk: 3
HS 번호: 2932209090
스토리지 클래스: 10 - Combustible liquids

화학 및 산업

응용 분야 · 1건

용도(R)-(+)-α-Hydroxy-γ-butyrolactone can be used as a starting material to synthesize: δ-Azaproline by reacting with benzyloxycarbonyl aminophthalimide via Mitsunobu reactions. Homochiral (R)-2,4-dihydroxybutyramide seco-pseudonucleoside reagents. Botryolide B via esterification and ring-closing metathesis reaction.Pregnane derivatives containing γ-butyrolactones as potential glucocorticoid agonists.