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기본 정보
- CAS
129741-57-7- 표준 SMILES
C=C(C)C1CCC2(C(=O)O[C@@H]3OC(CO[C@@H]4O[C@H](CO)[C@@H](O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)CC[C@@]3(C)[C@]4(C)CC[C@H]5[C@](C)(CO)[C@@H](OC6OC[C@H](O)[C@H](O)[C@H]6O[C@@H]6O[C@@H](C)[C@H](O)[C@@H](O)[C@H]6O)CC[C@]5(C)[C@H]4CC[C@]3(C)[C@@H]12- InChIKey
XLBRLNYIBZWSAV-ZCSAOVMRSA-N- 분자식
- C60H98O26
- 평균 분자량
- 1,235.418 g/mol
- 단동위원소 질량
- 1,234.63463326
이름 및 식별자
- 우선 이름
- PUBCHEM_71571504
- IUPAC
- 6-Deoxy-alpha-L-mannopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->6)-(5xi)-1-O-[(17xi)-3beta-{[2-O-(6-deoxy-alpha-L-mannopyranosyl)-L-arabinopyranosyl]oxy}-23-hydroxy-13-methyl-28-oxolup-20(29)-en-28-yl]-beta-D-xylo-hexopyranose
- 영어명
- PULCHINENOSIDE B4
- 분자식
- C59H96O26
- 분자량
- 1221.38
이름 및 동의어
Anemoside B4Pulchinenoside CAnemoside B4 Pulchinenoside B4Chinensioside APULCHINENOSIDE B4Pulsatilla saponin B4Pulchinenoside B4 CRSAnemosideB4 129741-57-7Pulchinenoside C (Standard)Pulchinenoside C (Anemoside B4)
데이터베이스 식별자
- CAS
129741-57-7- PubChem CID
- 71571504
- DTXSID
DTXSID00856145
물성
물리화학적 성질
- 녹는점
- 208 · 208-215℃
- 밀도
- 1.48 · 1.48
- 용해도
- 125 mg/mL · DMSO : 125 mg/mL (102.34 mM; Need ultrasonic)
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 12.5 · 12.50±0.70(Predicted)
- 색상
- White to light yellow
- 주요 응용
- 제약
- InChIKey
- OUHBKBTZUPLIIA-UFEMLMIJNA-N
화학 및 산업
응용 분야
개요Pulchinenoside B4 is a triterpenoid glycoside that has been found in P. chinensis and has diverse biological activities. It inhibits cisplatin-induced apoptosis, increases in reactive oxygen species (ROS) production, and decreases in superoxide dismutase (SOD) and catalase activities in HEK293 cells when used at concentrations of 6 and 12 μM. Pulchinenoside B4 (50 and 100 mg/kg twice per day) prevents increases in plasma blood urea nitrogen (BUN) and creatinine levels, markers of kidney injury, in a mouse model of cisplatin-induced nephrotoxicity. It prevents xylene-induced ear edema in mice in a dose-dependent manner. Pulchinenoside B4 (50 mg/kg) inhibits LPS-induced increases in serum TNF-α, IL-6, and IL-1β levels a mouse model of LPS-induced systemic inflammation.
용도Pulchinenoside C is a triterpenoid saponin extract which acts as a minor molluscicidal agent in addition to tumor necrosis factor-α secretion inhibition. Anti-inflammatory.
공급사100 곳
北京华美互利生物化工010-56205725 · [email protected]
成都普瑞法科技开发有限公司+86-028-82633397 18982077548 · [email protected]
成都曼思特生物科技有限公司18010516991 · [email protected]
南京普怡生物科技有限公司13814510036 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
成都健腾生物技术有限公司028-85159085 18080455027 · [email protected]
上海如吉生物科技发展有限公司+86-21-65211385-8001 36031160 · [email protected]
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