Azidocillin Potassium
기본 정보
- CAS
22647-32-1- 표준 SMILES
CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N=[N+]=[N-])c3ccccc3)C(=O)N2[C@H]1C(=O)[O-].[K+]- InChIKey
BNCKHYBJSCFJOI-YWUHCJSESA-M- 분자식
- C16H16KN5O4S
- 평균 분자량
- 413.5 g/mol
- 단동위원소 질량
- 413.05600667
개요
Azidocillin Potassium is the potassium salt of a narrow-spectrum, semisynthetic penicillin derivative with antibacterial activity. Azidocillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.
이름 및 식별자
- 우선 이름
- Azidocillin Potassium
- IUPAC
- potassium (2S,5R,6R)-6-[[(2R)-2-azido-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
이름 및 동의어
Azidocillin potassium22647-32-1UNII-7932098147DTXSID40177189AZIDOCILLIN POTASSIUM [WHO-DD]D-(-)-.ALPHA.-AZIDOBENZYLPENICILLIN POTASSIUM SALT4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, 6-((AZIDOPHENYLACETYL)AMINO)-3,3-DIMETHYL-7-OXO-, MONOPOTASSIUM SALT, (2S-(2.ALPHA.,5.ALPHA.,6.BETA.(S*)))-RefChem:116090DTXCID7099680D-(-)-ALPHA-AZIDOBENZYLPENICILLIN POTASSIUM SALT4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, 6-((AZIDOPHENYLACETYL)AMINO)-3,3-DIMETHYL-7-OXO-, MONOPOTASSIUM SALT, (2S-(2ALPHA,5ALPHA,6BETA(S*)))-4-Thia-1-Azabicyclo(3.2.0)Heptane-2-Carboxylic Acid,6-((Azidophenylacetyl)Amino)-3,3-Dimethyl-7-Oxo-, Monopotassium Salt, (2s-(2Alpha,5Alpha,6Beta(S*)))-
이름 더 보기
7932098147Q27231287Potassium (2S,5R,6R)-6-((R)-2-azido-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylatePotassium (2S,5R,6R)-6-{[(2R)-2-azido-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
물성
구조 계산 물성
- 극성 표면적
- 129 Ų
- 수소 결합 공여자 수
- 1
- 수소 결합 수용자 수
- 7
- 회전 가능 결합 수
- 4
- 무거운 원자 수
- 27
- 형식 전하
- 0
- 복잡도
- 666
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