기본 정보
- CAS
106656-86-4- 표준 SMILES
CC(C)NCC(O)COc1cccc2c1C=CC2- InChIKey
MPGBPFMOOXKQRX-UHFFFAOYSA-N- 분자식
- C15H21NO2
- 평균 분자량
- 247.33 g/mol
- 단동위원소 질량
- 247.15722891
개요
Indenolol is a drug of the beta-adrenergic blocker class.
이름 및 식별자
- 우선 이름
- Indenolol
- IUPAC
- 1-(1H-inden-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
- 현지명
- 인데놀롤
- 영어명
- indenolol
- 분자식
- C15H21NO2
- 분자량
- 247.33274
이름 및 동의어
Indenolol60607-68-3Sch 28316ZIndenololum3MZM7RWW00Sch-28316Z1-(7-indenyloxy)-3-isopropylaminopropan-2-ol.HClRefChem:790904DTXCID501506286DTXSID5010212381-(1H-inden-7-yloxy)-3-((1-methylethyl)amino)-2-propanol, hydrochloride1-(1H-inden-4-yloxy)-3-((propan-2-yl)amino)propan-2-ol
이름 더 보기
인데놀롤1-[(1H-Inden-4-yl)oxy]-3-(isopropylamino)-2-propanol1-(7-Indenyloxy)-3-isopropylamino-2-propanol hydrochloride
262-323-5106656-86-44-(2-Hydroxy-3-isopropylaminopropoxy)indene8GU15N96I81-(1H-inden-4-yloxy)-3-(propan-2-ylamino)propan-2-olUNII-8GU15N96I81-(Inden-4(or 7)-yloxy)-3-(isopropylamino)-2-propanol2-Propanol, 1-(1H-inden-4-yloxy)-3-((1-methylethyl)amino)-
데이터베이스 식별자
- CAS
106656-86-4、60607-68-3- PubChem CID
- 71955
- DTXSID
DTXSID70866817- ChEMBL
CHEMBL153585- UNII
- 8GU15N96I8
- EC Number
- 262-323-5
물성
구조 계산 물성
- XLogP
- 2.4
- 극성 표면적
- 41.5 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 3
- 회전 가능 결합 수
- 6
- 무거운 원자 수
- 18
- 형식 전하
- 0
- 복잡도
- 278
실험 및 물리화학적 성질
Melting Point147-148
물리화학적 성질
- 녹는점
- 88 · 88-89°
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Drugs used to cause dilation of the blood vessels.
응용 분야
용도Indenolol is a noncardioselective β-adrenoceptor blocking drug with partial agonist activity.
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상류 원료
공급사4 곳
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
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