2-아미노-4-클로로페놀

2-아미노-4-클로로페놀 · 4-클로로-2-아미노페놀 · 5-CHLORO-2-HYDROXYANILINE · Chlorzoxazone Related CoMpound A · c.i.76525 · C.I. 76525 · fouraminepy · Fouramine PY

https://huagongshe.com/ko/chemical/7265

식별자 및 물리적 특성

CAS No.	95-85-2
분자식	C6H6ClNO
평균 분자량	143.57 g/mol
단동위원소 질량	143.01379149 g/mol
SMILES	Nc1cc(Cl)ccc1O
InChIKey	SWFNPENEBHAHEB-UHFFFAOYSA-N
PubChem CID	7265
ChEMBL	CHEMBL251389
EC No.	202-458-9
DTXSID	DTXSID5024473
현지명	2-아미노-4-클로로페놀

화학 및 물리적 성질

XLogP	1.8
극성 표면적	46.3
수소 결합 공여자 수	2
수소 결합 수용자 수	2
회전 가능 결합 수	0
무거운 원자 수	9
형식 전하	0
복잡도	99.1
물질 분류	Nitrogen Compounds -> Amino Phenols
화장품	Cosmetic ingredients (4-Chloro-2-Aminophenol) -> CIR (Cosmetic Ingredient Review)Hair dyeing
LogP(분배 계수)	1.241.81
용해도	less than 1 mg/mL at 68 °F (NTP, 1992)Solubility in water, g/l at 26 °C: 3 (slightly soluble)2.3g/L
인화점	170 °C
Decomposition	170 °C
녹는점	284 to 286 °F (decomposes) (NTP, 1992)140 °C136-141 °C(lit.)
증기압	0.00141 [mmHg]Vapor pressure, Pa at 25 °C: 0.2
Physical Description	2-Amino-4-chlorophenol is a light brown colored crystalline solid. It may be toxic by ingestion. It is insoluble in water. It is used to make other chemicals.Brown solid[ICSC] Brown powder[Alfa Aesar MSDS]BROWN CRYSTALLINE POWDER WITH CHARACTERISTIC ODOUR.
자연 발화 온도	500 °C
끓는 점	185.5°C (rough estimate)
밀도	1.2028 (rough estimate)
굴절률	1.5618 (estimate)
저장 조건	2-8°C
pKa(산도 계수)	9.31±0.18(Predicted)
물리적 상태	고체
색상	옅은 오렌지색에서 밝은 갈색까지
용해도	불용성. 20°C에서 <0.1g/100mL
BRN	774859
안정성	안정적인. 강한 산화제와 호환되지 않습니다.
화장품 원료 기능	머리 염색
InChI	1S/C6H6ClNO/c7-4-1-2-6(9)5(8)3-4/h1-3,9H,8H2
InChIKey	SWFNPENEBHAHEB-UHFFFAOYSA-N
SMILES	Nc1cc(Cl)ccc1O
NIST	5-Chloro-2-hydroxyaniline(95-85-2)
EPA	2-Amino-4-chlorophenol (95-85-2)

화학적 성질

2-Amino-4-chlorophenol is a grayish to light brown crystalline solid or powder

안전 및 규제

GHS 분류	This chemical does not meet GHS hazard criteria for 15.5% (15 of 97) of reports.WarningH302 (84.5%): Harmful if swallowed [Warning Acute toxicity, oral]P203, P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 97 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Danger
규제 정보	Chemical: Phenol, 2-amino-4-chloro-Hazard Traits - CarcinogenicityStatus: Active Update: 23-11-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/102894-Chloro-2-aminophenol: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
기타 안전 정보	IMAP assessments - Phenol, 2-amino-4-chloro-: Environment tier I assessment
운송 라벨(DOT)	Poison
화재 위험	Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:· Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
건강 유해성	Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:· Highly toxic, may be fatal if inhaled, ingested or absorbed through skin.
유해성 요약	Causes contact dermatitis. [ChemIDplus] May cause skin sensitization[ICSC] A skin, eye, and mucous membrane irritant[NTP] A skin and strong eye irritantMay induce methemoglobinemiaToxic by ingestion[Alfa Aesar MSDS]
운송 번호 및 가이드(DOT)	2673 151

용도

Intermediate.

일반 설명

5-Chloro-2-hydroxyaniline is a light brown colored crystalline solid. 5-Chloro-2-hydroxyaniline may be toxic by ingestion. 5-Chloro-2-hydroxyaniline is insoluble in water. 5-Chloro-2-hydroxyaniline is used to make other chemicals.