3-Phosphoglyceraldehyde
5G · 1000g,5kg · LXJXRIRHZLFYRP-UHFFFAOYSA-N · DL-Glyceraldehyde 3-phosphate · Propal,2-hydroxy-3-(phosphonooxy)- · DL-GLYCERALDEHYDE 3-PHOSPHATE FREE A · Propanal, 2-hydroxy-3-(phosphonooxy)- · dl-glyceraldehyde 3-phosphate solution
식별자 및 물리적 특성
| CAS No. | 591-59-3 |
|---|---|
| 분자식 | C3H7O6P |
| 평균 분자량 | 170.06 g/mol |
| 단동위원소 질량 | 169.99802494 g/mol |
| SMILES | O=CC(O)COP(=O)(O)O |
| InChIKey | LXJXRIRHZLFYRP-UHFFFAOYSA-N |
| PubChem CID | 729 |
| ChEBI | CHEBI:17138 |
| EC No. | 209-721-7 |
| DTXSID | DTXSID40861814 |
화학 및 물리적 성질
| XLogP | -2.7 |
|---|---|
| 극성 표면적 | 104 |
| 수소 결합 공여자 수 | 3 |
| 수소 결합 수용자 수 | 6 |
| 회전 가능 결합 수 | 4 |
| 무거운 원자 수 | 10 |
| 형식 전하 | 0 |
| 복잡도 | 149 |
| 끓는 점 | 399.2±52.0 °C(Predicted) |
| 밀도 | 1.721±0.06 g/cm3(Predicted) |
| 저장 조건 | -20°C |
| 용해도 | Water: 50 mg/ml |
| pKa(산도 계수) | 1.80±0.10(Predicted) |
| 물리적 상태 | Liquid |
| 색상 | Colorless to light yellow |
| 생물학적 소스 | synthetic (organic) |
| InChI | InChI=1S/C3H7O6P/c4-1-3(5)2-9-10(6,7)8/h1,3,5H,2H2,(H2,6,7,8) |
| InChIKey | LXJXRIRHZLFYRP-UHFFFAOYSA-N |
| SMILES | C(=O)C(O)COP(O)(O)=O |
안전 및 규제
| GHS 분류 | DangerH314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]H318 (97.4%): Causes serious eye damage [Danger Serious eye damage/eye irritation]P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Hazard Classes and Categories | Skin Corr. 1B (100%)Eye Dam. 1 (97.4%) |
| 수질 위해 등급(WGK) | 3 |
| 운송 번호(UN) | UN 1760 8/PG 2 |
| 위험 문구(R) | 34 |
| 위험 표시 | C |
| 안전 문구(S) | 26-27-36/37/39-45 |
| 포장분류 | II |
| 위험 등급 | 8Eye Dam. 1Skin Corr. 1B |
| 저장 분류 | 8A - Combustible corrosive hazardous materials |
용도
개요
DL-Glyceraldehyde-3-phosphate (GADP) is an intermediate in several metabolic pathways, including glycolysis and gluconeogenesis. In glycolysis, it can be derived from fructose 1,6-bisphosphate by fructose bisphosphate aldolase in a reaction that also produces dihydroxyacetone phosphate (DHAP). Triose phosphate isomerase reversibly converts DHAP to GADP. GADP is processed to 1,3-bisphosphoglycerate by glyceraldehyde phosphate dehydrogenase and NAD+.
용도
The level of Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) activity in HEK 293 cells was aβeβed by measuring the reduction of NAD+ by DL-Glyceraldehyde 3-phosphate.