Unii-9M416Z9qnr
기본 정보
- CAS
78439-06-2- 표준 SMILES
CC(C)(O/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(C[n+]3ccccc3)CS[C@H]12)c1csc(N)n1)C(=O)[O-].O.O.O.O.O.[H+]- InChIKey
NMVPEQXCMGEDNH-TZVUEUGBSA-N- 분자식
- C22H32N6O12S2
- 평균 분자량
- 636.7 g/mol
- 단동위원소 질량
- 636.15196282
개요
See also: Ceftazidime Pentahydrate (preferred); Ceftazidime (broader); Avibactam (annotation moved to).
이름 및 식별자
- 우선 이름
- Unii-9M416Z9qnr
- IUPAC
- (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(2-carboxylatopropan-2-yloxyimino)acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;hydron;pentahydrate
- 영어명
- Ceftazidime pentahydrate
- 분자식
- C22H24N6O8S2
- 분자량
- 564.59
이름 및 동의어
UNII-9M416Z9QNRCeftazidime [USAN:USP:INN:BAN:JAN]1-(((6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)pyridinium hydroxide, inner salt, 7(sup 2)-(Z)-(O-(1-carboxy-1-methylethyl)oxime), pentahydratePyridinium, 1-((7-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-, hydroxide, inner salt, (6R-(6-alpha,7-beta(Z)))-, pentahydratePyridinium, 1-((7-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-, inner salt, pentahydrate, (6R-(6alpha,7beta(Z)))-CEFTAZIDIME PENTAHYDRATEKefazimCEFTAZIMECeftazidime RScazpentahydratesn401pentahydrategr20263pentahydrate
이름 더 보기
Ceftazidime USP/EP/BPCeftazidime 5-hydrateCeftazidieme Pentahydrate
물성
구조 계산 물성
- 극성 표면적
- 253 Ų
- 수소 결합 공여자 수
- 8
- 수소 결합 수용자 수
- 17
- 회전 가능 결합 수
- 7
- 무거운 원자 수
- 42
- 형식 전하
- 0
- 복잡도
- 1,020
물리화학적 성질
- 녹는점
- 1500 C · >1500C (dec.)
- 저장 조건
- 2 · 2-8°C
- 용해도
- 수용액에 난용성
- 산도 계수 (pKa)
- 1.8 · pKa 1.8 (Uncertain)
- 물리적 상태
- Solid
- 색상
- 하얀색
- 안정성
- 감광성, 수분 민감성
화학적 성질
White Solid
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- wgk
- 1
- HS 번호
- 29419000
- risk_code
- 42/43
- hazard_code
- Xn
- safety_code
- 22-36/37-45-37-24
화학 및 산업
응용 분야
개요Ceftazidime is the latest third generation cephalosporin to reach the market. It has one of the broadest spectrums of the cephalosporins, similar in many regards to that of cefotaxime. It is particularly active against Pseudomonas aeruginosa, being perhaps 4-5 times more potent in vitro than moxalactam and cefotaxime.
용도Ceftazidime pentahydrate is an antibacterial agent. It is used especially for Pseudomonas and other gram-negative infections in debilitated patients. It is used in the treatment of patients with infections caused by susceptible strains of organisms in the following diseases: lower respiratory tract infections,skin and skin structure infections, urinary tract infections, bacterial septicemia, bone and joint infections, gynecologic infections, intra abdominal infections (including peritonitis), and central nervous system infections (including meningitis).
상·하류 제품 정보
하류 제품
추가 설명
정의ChEBI: A hydrate that is the pentahydrate of ceftazidime, a cephalosporin having 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino and 3-pyridinium-1-ylmethyl side-groups.
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