Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
에틸렌 메타크릴레이트
디메타클릴레이트에틸렌글리콜 · 에틸렌글리콜디메타크릴산 · 에틸렌메타크릴레이트 · 에틸렌글리콜메타크릴산염 · 에틸렌글라이콜다이메타크릴레이트 · 글라이콜다이메타크릴레이트 · 에틸렌 메타크릴레이트 · 1,2-비스(메타크릴로일옥시)에테인
식별자 및 물리적 특성
| CAS No. | 97-90-5 |
|---|---|
| 분자식 | C10H14O4 |
| 평균 분자량 | 198.22 g/mol |
| 단동위원소 질량 | 198.08920893 g/mol |
| SMILES | C=C(C)C(=O)OCCOC(=O)C(=C)C |
| InChIKey | STVZJERGLQHEKB-UHFFFAOYSA-N |
| PubChem CID | 7355 |
| ChEMBL | CHEMBL1709582 |
| ChEBI | CHEBI:53436 |
| EC No. | 202-617-2 |
| DTXSID | DTXSID1026615 |
| 현지명 | 에틸렌 메타크릴레이트 |
화학 및 물리적 성질
| XLogP | 1.9 |
|---|---|
| 극성 표면적 | 52.6 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 4 |
| 회전 가능 결합 수 | 7 |
| 무거운 원자 수 | 14 |
| 형식 전하 | 0 |
| 복잡도 | 237 |
| Polymers | Plastics & Rubber -> (Meth)acrylates |
| 화장품 | Cosmetic ingredients (Ethylene glycol dimethacrylate) -> CIR (Cosmetic Ingredient Review)Cosmetic ingredients (Glycol Dimethacylate) -> CIR (Cosmetic Ingredient Review) |
| SpringerMaterials Properties | Viscosity |
| LogP(분배 계수) | 2.41.22 |
| 밀도 | 1.055 at 20 °C/20 °CRelative density (water = 1): 1.051.055 @ 20°C1.051 g/mL at 25 °C (lit.) |
| Viscosity | 3.03 mm²/s at 20 °C |
| 용해도 | > 10% in benzene> 10% in ethanol> 10% in ligroinSolubility in water, g/l at 20 °C: 1.1 (slightly soluble)<5g/L |
| 인화점 | 101 °C c.c.>230 °F |
| 끓는 점 | 260260 °C260 °C @760 [mm Hg]98-100 °C/5 mmHg (lit.) |
| Decomposition | When heated to decomp it emits acrid smoke and irritating fumes. |
| 녹는점 | -40 °C |
| 증기 밀도 | Relative vapor density (air = 1): 6.8>1 (vs air) |
| 증기압 | <0.1 mm Hg ( 21.1 °C) |
| 굴절률 | n20/D 1.454(lit.) |
| 저장 조건 | Store below +30°C. |
| 물리적 상태 | 액체 |
| 색상 | 무색~담황색 |
| 용해도 | 녹는 |
| BRN | 1776663 |
| 안정성 | 불안정 - 빛에 노출되면 중합될 수 있습니다. 강산, 강산화제, 강염기와 호환되지 않습니다. |
| 화장품 원료 기능 | 손톱 컨디셔닝 |
| InChI | 1S/C10H14O4/c1-7(2)9(11)13-5-6-14-10(12)8(3)4/h1,3,5-6H2,2,4H3 |
| InChIKey | STVZJERGLQHEKB-UHFFFAOYSA-N |
| SMILES | CC(=C)C(=O)OCCOC(=O)C(C)=C |
| LogP(분배 계수) | 2.4 at 20℃ |
| NIST | 2-Propenoic acid, 2-methyl-, 1,2-ethanediyl ester(97-90-5) |
| EPA | Ethylene glycol dimethacrylate (97-90-5) |
안전 및 규제
| GHS 분류 | WarningH317: May cause an allergic skin reaction [Warning Sensitization, Skin]P261, P271, P272, P280, P302+P352, P304+P340, P319, P321, P333+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)This chemical does not meet GHS hazard criteria for < 0.1% (1 of 1326) of reports.H317 (> 99.9%): May cause an allergic skin reaction [Warning Sensitization, Skin] |
|---|---|
| 규제 정보 | Chemical: 2-Propenoic acid, 2-methyl-, 1,2-ethanediyl ester2-Propenoic acid, 2-methyl-, 1,1'-(1,2-ethanediyl) ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2-Propenoic acid, 2-methyl-, 1,1'-(1,2-ethanediyl) ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 05-05-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/14351Ethylene glycol dimethacrylate: Does not have an individual approval but may be used under an appropriate group standard |
| 화재 위험 | Combustible. |
| 유해성 요약 | Allergic contact dermatitis reported in dental technicians, dental assistants, and a manufacturing worker (making rear-view mirrors)[Kanerva, p. 1749] A lachrymator[CHEMINFO] An eye and respiratory tract irritantNot a sensitizer in one study of guinea pigsEmergency treatment: Acrylates, multifunctional[HSDB] May polymerizeAn eye and respiratory tract irritantMay cause skin sensitization[ICSC] Danger of skin sensitization[MAK] An irritant[Aldrich MSDS] |
| TSCA 요건 | Section 8(a) of TSCA requires manufacturers of this chemical substance to report preliminary assessment information concerned with production, use, and exposure to EPA as cited in the preamble of the 51 FR 41329. |
| Chemical Dangers | The substance may polymerize. |
| Physical Dangers | Vapours are uninhibited and may polymerize, causing blockage of vents. |
| Hazard Classes and Categories | Skin Sens. 1 (> 99.9%)Specific target organ toxicity (single exposure) - category 3Skin sensitization - Category 1Skin sensitization - Category 1BSTOT SE 3 |
| Skin, Eye, and Respiratory Irritations | Irritating to eyes & respiratory system. |
| 소화 | Use water, foam, powder, carbon dioxide. |
| 응급 조치 | Fresh air, rest.Wear protective gloves when administering first aid. Remove contaminated clothes. Rinse and then wash skin with water and soap.Rinse with plenty of water (remove contact lenses if easily possible).Rinse mouth. |
| 안전 보관 | Store only if stabilized. Cool. Refer to the manufacturer's instructions for proper storage conditions. |
| 보관 조건 | Temp during storage must be kept low to minimize formation of peroxides and other oxidation products. ... Storage temp below 30 °C are recommended for the polyfunctional methacrylates. ... The methacrylate monomers should not be stored for longer than one year. Shorter storage times are recommended for the aminomethacrylates, ie, three months, and the polyfunctional methacrylates, ie, six months. Many of these cmpd are sensitive to UV light and should, therefore, be stored in the dark. The methacrylic esters may be stored in mild steel, stainless steel, or aluminum. /Methacrylic acid & derivatives/ |
| 누출 처리 | Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. |
| Preventive Measures | ... Hazard is the generation of considerable exothermic heat in some of the reactions, so that high pressures & temp may develop. This danger ... should be borne in mind when designing plant. Awareness of the dangers and of good engineering design are essential to safety. Employees should be instructed about the necessity of cleansing the skin if it is contaminated by materials which are irritants or skin-absorbed. With careful design, however, and complete enclosure of those processes where toxic chemicals or intermediates occur, dangerous exposures can be avoided. /Acrylic acid & derivatives/SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning. |
| Eye Prevention | Wear face shield. |
| Fire Prevention | NO open flames. |
| Inhalation Risk | No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C. |
| Skin Prevention | Protective gloves. Protective clothing. |
| Exposure Prevention | STRICT HYGIENE! |
| Ingestion Prevention | Do not eat, drink, or smoke during work. |
| 유해 작용 | Lacrimator (Lachrymator) - A substance that irritates the eyes and induces the flow of tears. |
| 노출 경로 | The substance can be absorbed into the body by inhalation, through the skin and by ingestion. |
| ICSC Environmental Data | The substance is harmful to aquatic organisms. |
| TSCA Test Submissions | The ability of ethylene dimethacrylate to induce mutations at the TK gene locus in L5178Y mouse lymphoma cells was evaluated in vitro. Cells were exposed to test article at concentrations ranging from 31.3 to 800 nl/ml both with and without Aroclor-induced rat liver S9 metabolic activation. In the presence of activation, a 2.4 to 10 fold increase in mutation frequency was observed in cells exposed to concentrations ranging from 400 to 700 nl/ml, while the percent relative growth decreased from 78.3 to 33.6%. In the absence of activation, exposure to concentrations of up to 800 nl/ml caused high toxicity but no increase in mutation rate. |
| Human Toxicity Excerpts | BIOLOGICALLY, METHACRYLATES RESEMBLE ACRYLATES, EXCEPT FOR LOWER REACTIVITY & THUS DECR TOXICITY. THIS IS PROBABLY DUE TO STERIC HINDRANCE BY ITS METHYL GROUP & IN TURN DECR RATES OF MEMBRANE TRANSPORT & SYSTEMIC TRANSLOCATION. /METHACRYLIC ESTERS/ |
| Non-Human Toxicity Excerpts | TWENTY-ONE DIFFERENT ACRYLATE & METHACRYLATE COMPOUNDS, INCLUDING ETHYLENE METHACRYLATE, WERE SCANNED FOR THEIR ABILITY TO INDUCE CONTACT SENSITIVITY, USING 5 DIFFERENT SENSITIZATION PROTOCOLS. CONTACT REACTIONS OF VARYING INTENSITIES WERE PRODUCED TO ALL THE MONO-, DI-, AND TRIACRYLATES TESTED. METHACRYLATES DID NOT SENSITIZE GUINEA PIGS. |
| 수질 위해 등급(WGK) | 1 |
| TSCA 등재 상태 | TSCA listed |
| RTECS 번호 | OZ4400000 |
| 운송 번호(UN) | UN 3334 |
| 독성 | LD50 orally in Rabbit: 3300 mg/kg |
| 관세 코드 | 29161490 |
| 위험 문구(R) | 37-43 |
| 위험 표시 | Xi |
| 안전 문구(S) | 24-37-36/37 |
| 기존화학 물질 | KE-24996 |
| F 고인화성물질 | 8-19 |
| 위험 등급 | Skin Sens. 1STOT SE 3 |
| 저장 분류 | 10 - Combustible liquids |
| 유해 물질 데이터 | 97-90-5(Hazardous Substances Data) |
용도
개요
The crosslinking agent of acrylic resins, ethyleneglycol dimethacrylate (EGDMA), is employed to optimize the dilution of high-viscosity monomers and to link together the macromolecules costituting the polymer. It caused contact dermatitis in dental technicians and dental assistants. A case was also reported in a car rear-view mirror manufacturer.
일반 설명
Ethylene glycol dimethylacrylate (EGDMA) is a diester formed by condensation of two equivalents of methacrylic acid and one equivalent of ethylene glycol.